Voltage-Sensitive Ion Channels, H. Richard Leuchtag

Автор: Peter C. Ruben
Название: Voltage Gated Sodium Channels
ISBN: 3642415873 ISBN-13(EAN): 9783642415876
Издательство: Springer
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Цена: 46118.00 р.
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Описание: A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.

Автор: Gerald Werner Zamponi
Название: Voltage-Gated Calcium Channels
ISBN: 1441934111 ISBN-13(EAN): 9781441934116
Издательство: Springer
Цена: 28732.00 р.
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Описание: oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar- macological targets in the treatment of a variety of disorders, such as epi- lepsy, hypertension, and pain. Voltage-gated calcium channels have there- fore been subject to intense study by numerous investigators over the past few decades, and an immense body of work has accumulated. In this book, we provide the first comprehensive overview of our current state of knowl- edge concerning this exciting field of research. Leading off with a general review of calcium signaling and techniques to measure calcium channel ac- tivity, the book delves into a provocative overview of the history of the cal- cium channel field, contributed by one of the key pioneers in the field. Dr. Richard Tsien. This is followed by an in depth review of the biochemical and molecular biological characterization of calcium channel genes by Drs. Catterall and Snutch whose research has resulted in major advances in the calcium channel field. A number of chapters are dedicated towards various aspects of calcium channel structure and function, including channel gat- ing, permeation, modulation and interactions with members of the exo- totic machinery--contributed by both established leaders and rising stars in the field.

Автор: Peter C. Ruben
Название: Voltage Gated Sodium Channels
ISBN: 3662512025 ISBN-13(EAN): 9783662512029
Издательство: Springer
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Цена: 43100.00 р.
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Описание: This volume of Springer`s Handbook of Experimental Pharmacology explores the wide range of factors relating to sodium channels, from their biophysical behavior, structure, and pathological vulnerabilities to the methodologies employed in studying them.

Автор: T. Narahashi
Название: Ion Channels
ISBN: 0306452243 ISBN-13(EAN): 9780306452246
Издательство: Springer
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Цена: 34799.00 р.
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Описание: `Further establishes the reputation of the series...an invaluable resource.` -Trends in Pharmacological Sciences, from a review of Volume 3 Volume 4 explores such emergent topics as: three-dimensional conceptions of ion channel proteins based on the available structural and functional data;

Автор: T. Narahashi
Название: Ion Channels
ISBN: 1461364663 ISBN-13(EAN): 9781461364665
Издательство: Springer
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Цена: 20962.00 р.
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Описание: In the past few years, the scientific community has witnessed significant progress in the study of ion channels. Gene cloning and monoclonal antibody techniques provide us with new approaches to the study of the molecular structure of ion channels.

Автор: M.J. Lab; Andre Kamkin; I. Lozinsky; Irina Kiselev
Название: Mechanosensitive Ion Channels
ISBN: 9048176387 ISBN-13(EAN): 9789048176380
Издательство: Springer
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Цена: 34799.00 р.
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Описание: This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research.

Автор: Boris Martinac
Название: Sensing with Ion Channels
ISBN: 3662500671 ISBN-13(EAN): 9783662500675
Издательство: Springer
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Цена: 27950.00 р.
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Описание: All living cells are able to detect and translate environmental stimuli into biologically meaningful signals. Sensations of touch, hearing, sight, taste, smell or pain are essential to the survival of all living organisms. The importance of sensory input for the existence of life thus justifies the effort made to understand its molecular origins. Sensing with Ion Channels focuses on ion channels as key molecules enabling biological systems to sense and process the physical and chemical stimuli that act upon cells in their living environment. Its aim is to serve as a reference to ion channel specialists and as a source of new information to non specialists who want to learn about the structural and functional diversity of ion channels and their role in sensory physiology.

Автор: Alfred Maelicke
Название: Molecular Biology of Neuroreceptors and Ion Channels
ISBN: 3642741576 ISBN-13(EAN): 9783642741579
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Proceedings of the NATO Advanced Research Workshop on Molecular Biology of Neuroreceptors and Ion Channels held on the Island of Santorini, Greece, October 2-7, 1988

Автор: T. Narahashi
Название: Ion Channels
ISBN: 1489917772 ISBN-13(EAN): 9781489917775
Издательство: Springer
Рейтинг:
Цена: 20962.00 р.
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Описание: `Further establishes the reputation of the series...an invaluable resource.` -Trends in Pharmacological Sciences, from a review of Volume 3 Volume 4 explores such emergent topics as: three-dimensional conceptions of ion channel proteins based on the available structural and functional data;

Автор: T. Narahashi
Название: Ion Channels
ISBN: 1461573041 ISBN-13(EAN): 9781461573043
Издательство: Springer
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Цена: 6986.00 р.
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Описание: A wealth of information has been accumulated about the function of ion channels of excitable cells since the extensive and pioneering voltage clamp studies by Hodgkin, Huxley, and Katz 36 years ago.