Описание: The book aims to present, educate and inform individuals about Alzheimer`s disease in a comprehensive manner.
Автор: Friel, Howard (book Author Who Writes About Foreign Policy, Public International Law, International Humanitarian Law, And Science-related Issues, Usa) Название: Paradigm shift to prevent and treat alzheimer`s disease ISBN: 0128122595 ISBN-13(EAN): 9780128122594 Издательство: Elsevier Science Рейтинг: Цена: 13298.00 р. Наличие на складе: Поставка под заказ.
Описание:
A Paradigm Shift to Prevent and Treat Alzheimer's Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer's disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years.
These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gallate (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth.
This book also presents a new analytical framework that convincingly favors a multi-targeting (pleiotropic) approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model.
A Paradigm Shift to Prevent and Treat Alzheimer's Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers.
Автор: Kevin Morgan; Minerva M. Carrasquillo Название: Genetic Variants in Alzheimer`s Disease ISBN: 1489997997 ISBN-13(EAN): 9781489997999 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers recent research which has identified nine new genes, and the vital realization that new pathways could be involved in the pathogenesis of Alzheimer`s. These are now targets for therapeutic intervention, which might one day lead to a cure.
Автор: Budson Название: The Handbook of Alzheimer`s Disease and Other Dementias ISBN: 1118672852 ISBN-13(EAN): 9781118672853 Издательство: Wiley Рейтинг: Цена: 4744.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This is a broad-ranging review of the current research on Alzheimer`s disease and other dementias from both basic neuroscience and clinical perspectives. It provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances in a single volume.
Автор: Atta-ur-Rahman Название: Drug Design and Discovery in Alzheimer`s Disease ISBN: 0128039590 ISBN-13(EAN): 9780128039595 Издательство: Elsevier Science Рейтинг: Цена: 15159.00 р. Наличие на складе: Поставка под заказ.
Описание:
Drug Design and Discovery in Alzheimer's Disease includes expert reviews of recent developments in Alzheimer's disease (AD) and neurodegenerative disease research. Originally published by Bentham as Frontiers in Drug Design and Discovery, Volume 6and now distributed by Elsevier, this compilation of the sixteen articles, written by leading global researchers, focuses on key developments in the understanding of the disease at molecular levels, identification and validation of molecular targets, as well as innovative approaches towards drug discovery, development, and delivery. Beginning with an overview of AD pharmacotherapy and existing blockbuster drugs, the reviews cover the potential of both natural and synthetic small molecules; the role of cholinesterases in the on-set and progression of AD and their inhibition; the role of beta-site APP clearing enzyme-1 (BACE-1) in the production of -amyloid proteins, one of the key reasons of the progression of AD; and other targets identified for AD drug discovery.
Edited and written by leading experts in Alzheimer's disease (AD) and other neurodegenerative disease drug development
Describes existing drugs for AD and current molecular understanding of the condition
Reviews recent advances in the field, including coverage of cholinesterases, BACE-1, and other drug development targets
Описание: Recent advances in genetics and brain biochemistry point to the Abeta peptide as the major culprit in causing neurodegeneration in Alzheimer’s Disease (AD). Abeta Peptide and Alzheimer’s Disease is specifically targeted at summarizing current knowledge of the Abeta peptide and its role in AD. Written by leaders in the industrial and academic world specializing in this rapidly moving area, the book covers fundamental biochemical studies on this peptide, the genetic impact on Abeta expression and processing, and various AD therapeutic strategies that target Abeta. Although specifically focusing on the Abeta peptide and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases, such as prion disease, Parkinsons and Huntingtons. This book will primarily be of interest to AD researchers and clinicians but also to researchers of other amyloid diseases.
Автор: Orly Lazarov Название: Genes, Environment and Alzheimer`s Disease ISBN: 0128028513 ISBN-13(EAN): 9780128028513 Издательство: Elsevier Science Рейтинг: Цена: 11620.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. . It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
