Описание: Distinguished researchers and clinicians review the biological and biomedical aspects of gasotransmitters, emphasizing signaling transduction mechanisms in general, and ion channel regulation in particular. The authors discuss the endogeneous metabolism and regulation of gasotransmitters, their toxicological profiles and biological actions, and their interactions in terms of their production and effects. The physiological roles of NO, CO, and H2S in the regulation of the cardiovascular, neuronal, and gastrointestinal systems, as well as of cell metabolism, are also reviewed, along with the interaction of the gastrotransmitters with KATP,KCa voltage-gated Ca2+, voltage-gated Na+, and cyclic nucleotide-gated ion channels.
Автор: Kalyuzhny Название: Signal Transduction Immunohistochemistry ISBN: 1617790230 ISBN-13(EAN): 9781617790232 Издательство: Springer Рейтинг: Цена: 20263.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Unlike detecting constitutively expressed targets, immunohistochemical detection of labile, low abundance, and short-lived signal transduction molecules can be a very difficult task. In Signal Transduction Immunohistochemistry: Methods and Protocols, IHC experts contribute detailed protocols addressing the numerous challenges of signal-transduction immunohistochemistry (ST-IHC). Beginning with a set of introductory chapters, the volume moves on to cover techniques used for the preservation of antigens and their unmasking, protocols in digital imaging and image analysis of stained cells and tissues, high-throughput data collection and data analysis, and techniques used in neuroscience as well as cancer and stem cell research. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Signal Transduction Immunohistochemistry: Methods and Protocols serves as an ideal guide for novices and as a bastion of inspiring ideas to be exploited by experienced researchers on the lookout for new experimental tricks and hints.
Описание: Relates the biological phenomena to the underlying biochemical processes. Aimed at advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis.
Автор: Anton Hermann; Guzel F. Sitdikova; Thomas M. Weige Название: Gasotransmitters: Physiology and Pathophysiology ISBN: 3642446523 ISBN-13(EAN): 9783642446528 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This richly illustrated expert review of the biological, pharmacological and medical functions of the signaling molecules nitric oxide, carbon monoxide, and hydrogen sulfide collates the impressive quantity of fresh data accumulated in recent years.
Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology, biochemistry, bioinformatics, and pharmacology, as well as medical students. The text is organized by three key topics central to signal transduction: the protein network, its energy supply, and its evolution. It covers all important aspects of cell signaling, ranging from prokaryotic signal transduction to neuronal signaling, and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes, as well as content on new developments in systems biology, epigenetics, redox signaling, and small, non-coding RNA signaling.
Автор: A.E. Evangelopoulos; J.P. Changeux; L. Packer; T.G Название: Receptors, Membrane Transport and Signal Transduction ISBN: 3642742025 ISBN-13(EAN): 9783642742026 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Study Institute on Receptors, Membrane Transport and Signal Transduction held on the Island of Spetsai, Greece, August 16-27, 1988
Автор: Elliott M. Ross; Karel W.A. Wirtz Название: Biological Signal Transduction ISBN: 3642751385 ISBN-13(EAN): 9783642751387 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Institute on Biological Signal Transduction held on the Island of Spetsai (Greece), August 6 - 17, 1990
Автор: Anthony J. Pawson Название: Protein Modules in Signal Transduction ISBN: 3642804837 ISBN-13(EAN): 9783642804830 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: L.M.G. Heilmeyer Название: Signal Transduction and Protein Phosphorylation ISBN: 1475701683 ISBN-13(EAN): 9781475701685 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Herbert Waldmann; G. Dorman; P.J. Hergenrother; C. Название: Bioorganic Chemistry of Biological Signal Transduction ISBN: 3662146975 ISBN-13(EAN): 9783662146972 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Yusuf A. Hannun Название: Sphingolipid-Mediated Signal Transduction ISBN: 3662224275 ISBN-13(EAN): 9783662224274 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Lipid-derived molecules are increasingly appreciated as key regulators of cell responses and signal transduction. Sphingolipid-derived bioactive molecules are emerging as critical regulators of some of the most exciting and, until recently, poorly-understood areas of biology such as growth suppression, programmed cell death and tumor invasion.
Автор: S. Kito Название: Neuroreceptors and Signal Transduction ISBN: 1475759738 ISBN-13(EAN): 9781475759730 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since the first Hiroshima Symposium of Neurotransmitter Receptors in 1983, there have been conspicuous advances in this field.
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