Adrenal Disorders, Andrew N. Margioris; George P. Chrousos

Автор: Eliza B. Geer
Название: The Hypothalamic Pituitary Adrenal Axis in Health and Disease
ISBN: 3319459481 ISBN-13(EAN): 9783319459486
Издательство: Springer
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Описание: Cushing?s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.

Автор: Snyder Richard
Название: Adrenal Fatigue for Dummies
ISBN: 1118615808 ISBN-13(EAN): 9781118615805
Издательство: Wiley
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Описание: The easy way to take charge of your adrenal health Despite their small size, the adrenal glands play an important role in the body, producing numerous hormones that impact our development and growth, affect our ability to deal with stress, and help to regulate kidney function.

Автор: Linos
Название: Adrenal Glands
ISBN: 3642074324 ISBN-13(EAN): 9783642074325
Издательство: Springer
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Цена: 32004.00 р.
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Описание: - Over 200 exquisite illustrations, ranging from intraoperative photographs, line drawings, diagnostic images, pathology slides, tables and graphs are available to make each case discussed comprehensible and easy to follow.

Автор: Hindmarsh, Peter C
Название: Congenital Adrenal Hyperplasia
ISBN: 0128114835 ISBN-13(EAN): 9780128114834
Издательство: Elsevier Science
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Описание:

Congenital Adrenal Hyperplasia: A Comprehensive Guide addresses how hydrocortisone works, what can go wrong, and how to correct it, also explaining why the timing of doses and measurement of cortisol from a dose is extremely important.

Автор: A.M. Neville; M.J. O`Hare
Название: The Human Adrenal Cortex
ISBN: 1447113195 ISBN-13(EAN): 9781447113195
Издательство: Springer
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Автор: M.I. New; L.S. Levine
Название: Congenital Adrenal Hyperplasia
ISBN: 3642820131 ISBN-13(EAN): 9783642820137
Издательство: Springer
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Цена: 18167.00 р.
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Описание: Congenital adrenal hyperplasia (CAH) consists of a group of disorders of adrenal steroidogenesis. Each disorder results from an inherited deficiency of one of the several enzymes necessary for normal steroid synthesis. The different enzyme deficiencies produce characteristic patterns of hormonal abnormalities; the clinical symptoms of the different forms of CAH depend on the particular hormones that are deficient or that are produced in excess. The earliest documented description of CAH was by DeCrecchio in 1865 (DeCrecchio 1865). This Neapolitan anatomist described a cadaver having a penis with first degree hypospadias but no externally palpable gonads. Dis- section revealed a vagina, uterus, fallopian tubes, ovaries, and markedly enlarged adrenals. It is interesting that the subject suffered a confusion of sex assignment, being declared a female at birth and a male 4 years later. He conducted himself as a male sexually and socially. Since the original descrip- tion of this case, investigators have unravelled the pathophysiology of the inborn errors of steroidogenesis. 1 Steroidogenesis and Enzymatic Conversions of Adrenal Steroid Hormones A. Steroidogenesis The adrenal synthesizes three main classes of hormones: mineralocorticoids (17-deoxy pathway), glucocorticoids (17-hydroxy pathway), and sex steroids.