Central Nervous System Diseases, Dwaine F. Emerich; Reginald L. Dean III; Paul R. S
Автор: Firas H. Kobeissy et al Название: Injury Models of the Central Nervous System ISBN: 1493938142 ISBN-13(EAN): 9781493938148 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume discusses experimental brain injury models thatcontain valuable information carefully chosen to widen the researchers’ horizonabout neurotrauma. Injury Models of Central Nervous System: Methods and Protocols contains relevant experimental design approaches that have beenadapted and made ready for application in laboratory settings. For easiernavigation, the chapters are categorized into 6 parts: Introduction, GeneralConsideration in Using Animal Laboratory in CNS Injury Research, Classical TBIModels and Their Link with Pathophysiological Features of CBS Injury – Models,Special Topics in CNS Trauma: Comorbid Conditions in CNS Injury, OutcomeMeasures in Brain Injury Models, and Future Directions. Written in the highly successful Methods inMolecular Biology series format, chapters include introductions to theirrespective topics, lists of the necessary materials and reagents, step-by-step,readily reproducible laboratory protocols, and tips on troubleshooting andavoiding known pitfalls.Practical and thorough, Injury Models of Central Nervous Systems: Methods and Protocols, is a very useful reference towards theprogress of this discipline.
Автор: Moneeb Ehtesham Название: Stem Cell Biology in Neoplasms of the Central Nervous System ISBN: 3319165364 ISBN-13(EAN): 9783319165363 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.
Автор: M.A. Hayat Название: Tumors of the Central Nervous System, Volume 13 ISBN: 9402402810 ISBN-13(EAN): 9789402402810 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Volume 13: Pineal, Pituitary, and Spinal Tumors is organized in six sections, for convenience and quick access to critical information. Section I, Types of Tumors includes a chapter on molecular characterization of Embryonal tumors, a chapter on diagnosis of metastatic oligodendroglioma using fine-needle aspiration cytology, one covering intra-arterial chemotherapy of oligodendroglial tumors and another on the role of cyclooxygenase-2 in the development and growth of Schwannomas, and others, closing with a chapter on trigeminal neuralgia with cerebellopontine angle tumors. Section II, Diagnosis, includes two chapters on cell counting in histopathologic slides of tumors. Section III offers three chapters which discuss aspects of intraoperative ultrasonography. Section IV covers brain tumor surgery, and Section V surveys Brain Metastasis. The final section offers a wide-ranging review of General Diseases, with chapters on, among others, Alexander Disease; Lipoma; Transplantation of human umbilical cord blood mononuclear cells in cases of neonatal hypoxic-ischemic brain damage; and a chapter discussing the use of mobile phones and brain cancer risk in children. Like its twelve predecessors in the series, this volume merits distinction for its thorough approach, its roster of 78 distinguished contributors representing 14 different countries and its detailed examination of leading-edge technology and methods.
Автор: Dwaine F. Emerich; Reginald L. Dean III; Paul R. S Название: Central Nervous System Diseases ISBN: 089603724X ISBN-13(EAN): 9780896037243 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A critical review of the animal models used in developing powerful new therapies for central nervous system diseases. Techniques that rely heavily on behavioural analyses, as well as models developed from infusions of neurotoxins and from advances in molecular biology, are thoroughly explicated.
Автор: Donald Bayley Tower; Melvin D. Yahr Название: PROPERTIES of MEMBRANES and Diseases of the Nervous System ISBN: 3662386631 ISBN-13(EAN): 9783662386637 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Walter Hendelman, Peter Humphreys and Christopher Название: The Integrated Nervous System ISBN: 1420045970 ISBN-13(EAN): 9781420045970 Издательство: Taylor&Francis Рейтинг: Цена: 10411.00 р. Наличие на складе: Поставка под заказ.
Описание: To demonstrate the connection between academic neuroanatomy and the practice of clinical neurology, this innovative textbook presents carefully chosen clinical cases that illustrate how the nervous system is constructed and how it functions under normal circumstances. Providing the foundation needed to encounter neurological diseases, it teaches students and residents how to integrate a patient?s clinical history and examination with neuroanatomy. In addition to color illustrations throughout, the book adds an invaluable DVD for further exploration and access to a state-of-the-art website with additional materials that are updated periodically.
Автор: Hayat Название: Tumors of the Central Nervous System, Volume 13 ISBN: 9400776012 ISBN-13(EAN): 9789400776012 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Coverage in this book includes diagnosis, intraoperative ultrasonography, cell counting, and brain metastasis. It examines a range of tumor types, including neuroblastoma, medulloblastoma, meningioma, and chordoma.
Nanomedicine in Central Nervous System Injury and Repair (IRN), Volume 137, the latest release in the International Review of Neurobiology series presents comprehensive chapters that cover a broad range of topics, including, but not limited to, how Diabetes exacerbates methamphetamine induced blood-brain barrier breakdown, edema formation, oxidative stress and myelin damage, and how Focal blast brain injury induces rapid edema formation, blood-brain barrier breakdown and intensive cellular damage. In addition, the Neuroprotective effects of a multimodal drug cerebrolysin are explored, as is how Nanowired cerebrolysin potentiates neuroprotective effects of histamine H3 receptor inverse agonist and antagonist with partial H4 agonist in Alzheimer's Disease.
This series reviews current knowledge and understanding on how to repair the damaged spinal cord and brain with nanomedicine, detailing new therapeutic advances and providing a starting point for researchers and practitioners entering the field.
Provides cutting-edge research on the damaged spinal cord and brain
Presents new therapeutic advances
Reviews current knowledge and understanding
Автор: Klaus Ballanyi Название: Isolated Central Nervous System Circuits ISBN: 1493961837 ISBN-13(EAN): 9781493961832 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Neuromethods series volume offers protocols and examples for exciting results from the labs of renowned experts. Covers patch-clamp, multiphoton imaging, live fluorescent protein expression, immunohistochemistry techniques, `organotypic` slices and more.
Описание: This volume will cover what is known regarding the biology and treatment of CNS metastasis, including novel chapters such as the future of targeted therapies. It will begin with an overview of the natural history and risk factors for CNS metastases that will broadly cover all cancer histologies. This will be followed by 3 chapters that will cover the biology. These include: molecular biology, discussing what is known about specific genes/proteins involved in the process and model systems to study brain metastasis; the brain microenvironment, focusing on how it is different from the microenvironment of other organs of the body; and the blood-brain barrier, which includes a discussion of permeability with respect to brain metastases. A chapter on experimental imaging will cover both the biology of brain metastasis from an imaging perspective and use of imaging techniques to study brain metastases. The clinical chapters will discuss treatment options with separate chapters on surgery, chemotherapy and radiation. In addition, leptomeningeal metastasis will be given its own chapter. Finally, quality of life issues will be the concluding chapter.
Автор: Alexander G. Karczmar; N. Chauhan; V.P. Whittaker; Название: Exploring the Vertebrate Central Cholinergic Nervous System ISBN: 148997895X ISBN-13(EAN): 9781489978950 Издательство: Springer Рейтинг: Цена: 40389.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction: History and Scope of This Book.- Cholinergic Cells and Pathways.- Metabolism of Acetylcholine: Synthesis and Turnover.- History of Research on Nicotinic and Muscarinic Cholinergic Receptors.- Muscarinic Acetylcholine Receptors in the Central Nervous System: Structure, Function, and Pharmacology.- Neuronal Nicotinic Receptors: History, Structure, and Functional Roles.- Anticholinesterases and War Gases.- Cholinergic Aspects of Growth and Development.- Central Cholinergic Nervous System and Its Correlates.- Links Between Amyloid and Tau Biology in Alzheimer's Disease and Their Cholinergic Aspects.- Envoi
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