Alkaloids, Margaret F. Roberts

Автор: S. William Pelletier
Название: Alkaloids: Chemical and Biological Perspectives
ISBN: 1461277159 ISBN-13(EAN): 9781461277156
Издательство: Springer
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Описание: Volume 8 of this series presents four timely reviews on alkaloids: Chapter 1 is a magnificent and monumental review of curare, "a group of dart and/or arrow poisons varying in composition and featuring muscle relaxation as their basic pharmacological action."

Автор: Margaret F. Roberts
Название: Alkaloids
ISBN: 0306454653 ISBN-13(EAN): 9780306454653
Издательство: Springer
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Цена: 36570.00 р.
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Описание: Featuring leaders in the field of Alkaloids, this book presents both the historical use of alkaloids and the discoveries in the biochemistry of alkaloid production in plants alkaloid ecology, including marine invertebrates, animal and plant parasites, and alkaloids as antimicrobial and medicinal use.

Автор: Brian Robinson
Название: The Calabar Bean and its Alkaloids
ISBN: 9402411909 ISBN-13(EAN): 9789402411904
Издательство: Springer
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Цена: 23757.00 р.
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Описание: Investigations into Calabar beans (the dried ripe seeds of Physostigma venenosum) and their alkaloidal components compose a classical scientific journey throughout some one-and-a-half centuries and not only represent a fascinating aspect of the history of medicine but which is, moreover, still ongoing at the forefront of chemical and medical discovery. Those in particular involving its major such component, l-physostigmine, have led to an understanding of some of the fundamental mechanisms occurring in physiology, pharmacology and biochemistry and, either actually or potentially (by providing a template and thereby acting as a “lead compound”) have provided a useful treatment for a variety of neurological disorders associated with irregularities in cholinergic transmission in which augmentation of cholinergic activity has proved to be beneficial. Physostigma venenosum is distributed throughout equatorial West Africa and having a colourful history – by virtue of their former use as an ordeal poison in trials for witchcraft in the Efik society of Old Calabar – are its dried ripe seeds (Calabar beans). The major toxic compound isolated from these, l-physostigmine, which is also known as eserine and is the only alkaloid as yet also to be isolated from a microbial source (along with l-N(8)-norphysostigmine) and is the first alkaloid found to contain a 1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole ring system, and the first natural product found to contain a carbamyl group. It also became one of the first examples whereby the mechanism of action of a drug could be defined at the molecular level relatively simply, played a crucial role in the Nobel Prize – winning discovery of the mechanism of neurohumoral transmission, and has led to products for the treatment of a wide range of disorders associated with deficiencies in cholinergic transmission. Several other alkaloids have also been isolated from the Calabar bean. For some of these, structures have been established, syntheses effected and pharmacology investigated.

Автор: J.W. Gorrod; J. Wahren
Название: Nicotine and Related Alkaloids
ISBN: 940104936X ISBN-13(EAN): 9789401049368
Издательство: Springer
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Цена: 15672.00 р.
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Описание: Nicotine is an alkaloid which is present, together with a number of minor alkaloids, in tobacco and a wide variety of other plants.

Автор: R.A. Anderson; Hans-Ferdinand Linskens; J.C. Calla
Название: Alkaloids
ISBN: 3642842283 ISBN-13(EAN): 9783642842283
Издательство: Springer
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Цена: 18284.00 р.
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Описание: It is refreshing to find a book treating alkaloid analysis with all the latest techniques such as inverse-detected two dimensional NMR, GC/MS, and HPLC associated techniques.

Автор: J.D. Phillipson; M.F. Roberts; M.H. Zenk
Название: The Chemistry and Biology of Isoquinoline Alkaloids
ISBN: 3642701302 ISBN-13(EAN): 9783642701306
Издательство: Springer
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Цена: 20896.00 р.
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Описание: Based on Lectures Presented at a Symposium

Автор: Trevor Robinson
Название: The Biochemistry of Alkaloids
ISBN: 3642618324 ISBN-13(EAN): 9783642618321
Издательство: Springer
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Цена: 18284.00 р.
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Описание: The alkaloids were of great importance to mankind for centuries, long before they were recognized . Since that time they have remained of great interest to chemists, and now in any month there appear dozens of publications dealing with the isolation of new alkaloids or the determination of the structures of previously known ones.