U. Feige; R.I. Morimoto; Barbara Polla Stress-Inducible Cellular Responses 9783034899017

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Автор: U. Feige; R.I. Morimoto; Barbara Polla
Название: Stress-Inducible Cellular Responses
ISBN: 9783034899017
Издательство: Springer
Классификация:

Медицинское оборудования и методики его эксплуатации

Медицинские исследования

Науки о жизни (медико-биологические): общие вопросы

ISBN-10: 3034899017
Обложка/Формат: Paperback
Страницы: 495
Вес: 0.81 кг.
Дата издания: 17.09.2011
Серия: Experientia Supplementum
Язык: English
Размер: 244 x 170 x 26
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Stress-Inducible Cellular Responses are essential for survival of cells of all species under adverse conditions. At the molecular level this is ac- complished by a number of essential proteins all of which are involved in various aspects of cellular homeostasis through protective or adaptive func- tions. Interestingly, molecules such as heat shock proteins have properties as molecular chaperones and are involved in multiple stages of a protein biogenesis beginning with synthesis and involvement in the subsequent events of folding, translocation, and degradation. Heat shock proteins have a critical role to stabilize folding intermediates and to prevent protein aggregation. In addition, stress-proteins serve as targets for immune re- sponses in immune homeostasis and during infections. The term Stress Response reflects the rapid growth and breadth of this field which includes the molecular and cellular response to drugs, UV irra- diation, oxidative stress, and environmental toxins. Radical scavengers such as superoxide dismutases and inducible regulatory proteins of metall- ic ion status such as ferritin and protein disulfide isomerases are also con- sidered within the frame of stress proteins and represent a new and growing class of stress responses.

Stress-Inducible Cellular Responses, U. Feige; R.I. Morimoto; Barbara Polla