Aging and Recovery of Function in the Central Nervous System, Stephen W. Scheff
Автор: Kerry L. Tucker; Tamara Caspary Название: Cilia and Nervous System Development and Function ISBN: 9401782954 ISBN-13(EAN): 9789401782951 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text embraces the welter of recent research on the crucial role played by cilia in the development and activity of the central nervous system. It features cutting-edge analysis by lead researchers into cilia`s functions in the brain and spinal cord.
Автор: Walter Hendelman, Peter Humphreys and Christopher Название: The Integrated Nervous System ISBN: 1420045970 ISBN-13(EAN): 9781420045970 Издательство: Taylor&Francis Рейтинг: Цена: 10411.00 р. Наличие на складе: Поставка под заказ.
Описание: To demonstrate the connection between academic neuroanatomy and the practice of clinical neurology, this innovative textbook presents carefully chosen clinical cases that illustrate how the nervous system is constructed and how it functions under normal circumstances. Providing the foundation needed to encounter neurological diseases, it teaches students and residents how to integrate a patient?s clinical history and examination with neuroanatomy. In addition to color illustrations throughout, the book adds an invaluable DVD for further exploration and access to a state-of-the-art website with additional materials that are updated periodically.
Автор: M.A. Hayat Название: Tumors of the Central Nervous System, Volume 14 ISBN: 9402404228 ISBN-13(EAN): 9789402404227 Издательство: Springer Рейтинг: Цена: 16977.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This fourteenth volume of the series provides comprehensive, current information on the diagnosis, therapy and prognosis of brain tumors and spinal tumors. For the readers` convenience, contributions are organized into three categories of Pineal Tumors, Pituitary Tumors, and Spinal Tumors.
Автор: Brodal Название: The Central Nervous System.2003 ISBN: 0195165608 ISBN-13(EAN): 9780195165609 Издательство: Oxford Academ Цена: 8712.00 р. Наличие на складе: Поставка под заказ.
Описание: A major goal of this well-established textbook is to provide knowledge and understanding of neuroscience as a basis for clinical thinking. The strong emphasis on linking basic sciences with their clinical application has implications for the choices of which topics to treat in depth and which to treat more summarily - making this different from most other neuroscience textbooks. For example, topics of great practical importance like the cranial nerves, the autonomic nervous system, and pain are treated in depth.
Автор: Ballanyi Название: Isolated Central Nervous System Circuits ISBN: 1627030190 ISBN-13(EAN): 9781627030199 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Advances in methodologies and experimental models are pivotal to furthering our understanding of central nervous system (CNS) functions in mammals. Isolated Central Nervous System Circuits examines the application a variety of technologies to mostly active in vitro preparations from basically different CNS regions with a diversity of functions. From patch-clamp, multiphoton imaging, live fluorescent protein expression, or immunohistochemistry techniques to acute or 'organotypic' slices and en bloc preparations, this detailed volume features key protocols and examples for exciting results from the labs of renowned experts. Written for the popular Neuromethods series, chapters include the kind of thorough implementation advice that is vital for achieving successful results. Comprehensive and cutting-edge, Isolated Central Nervous System Circuits will greatly aid scientists to further improve models and to develop corresponding models of not yet intensively studied structures such as nucleus ruber, superior colliculus, or basal ganglia.
Автор: Kewal K. Jain Название: Drug Delivery to the Central Nervous System ISBN: 1493961594 ISBN-13(EAN): 9781493961597 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain.
Автор: Bruno P. Guiard; Giuseppe Di Giovanni Название: 5-HT2A Receptors in the Central Nervous System ISBN: 3319704729 ISBN-13(EAN): 9783319704722 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 5-HT2A receptors are G-protein coupled receptors that are widely distributed throughout the brain, most notably on neuronal and glial cells. 5-HT2A receptors have been implicated in various central physiological functions including mood regulation, memory, sleep, nociception, eating, and reward behaviors, and they are also believed to control the cardiovascular system. This book provides a comprehensive overview of these receptors including sections on their properties and distribution, approaches for their study, their role in a number of brain functions and diseases, and their role as therapeutic targets. ?
Автор: M.A. Hayat Название: Tumors of the Central Nervous System, Volume 9 ISBN: 9402406581 ISBN-13(EAN): 9789402406580 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume deals with various aspects of nine separate types of brain tumor. With almost 70 contributors from 17 nations, the edition offers an unrivalled thoroughness and breadth of coverage that includes the very latest research material.
Автор: Damir Janigro Название: The Cell Cycle in the Central Nervous System ISBN: 1493963341 ISBN-13(EAN): 9781493963348 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cell Cycle During the Development of the Mammalian Central Nervous System.- Methodological Considerations in the Evaluation of the Cell Cycle in the Central Nervous System.- Neural Stem Cells.- Progenitors and Precursors of Neurons and Glial Cells.- Vasculogenesis and Angiogenesis.- Neuronal Migration and Malformations of Cortical Development.- Postnatal Development of Neurons and Glia.- Genome-Wide Expression Profiling of Neurogenesis in Relation to Cell Cycle Exit.- Neurogenesis and Apoptotic Cell Death.- Ion Channels and the Cell Cycle.- Nonsynaptic GABAergic Communication and Postnatal Neurogenesis.- Critical Roles of Ca2+ and K+ Homeostasis in Apoptosis.- Mammalian Neural Stem Cell Renewal.- Control of the Cell Cycle and Apoptosis in Glia.- Methods of Determining Apoptosis in Neuro-Oncology.- Cell Cycle, Neurological Disorders, and Reactive Gliosis.- Potassium Channels, Cell Cycle, and Tumorigenesis in the Central Nervous System.- Adult Neurogenesis: A Mechanism for Brain Repair?.- Enhanced Neurogenesis Following Neurological Disease.- Endothelial Injury and Cell Cycle Re-Entry.- The Contribution of Bone Marrow-Derived Cells to Cerebrovascular Formation and Integrity.- Microvessel Remodeling in Cerebral Ischemia.- Vascular and Neuronal Effects of VEGF in the Nervous System.- Epidermal Growth Factor Receptor in the Adult Brain.- Cell Cycle Re-Entry: A Mechanism of Brain Disease?.- Neurodegeneration and Loss of Cell Cycle Control in Postmitotic Neurons.- Cell Cycle Activation and the Amyloid-? Protein in Alzheimer's Disease.- Neuronal Precursor Proliferation and Epileptic Malformations of Cortical Development.- Vascular Differentiation and the Cell Cycle.- Adult Neurogenesis and Central Nervous System Cell Cycle Analysis.- Neurogenesis in Alzheimer's Disease.- The Biology of Gliomas.- p53 and Multidrug Resistance Transporters in the Central Nervous System.- Signaling Modules in Glial Tumors and Implications for Molecular Therapy.- Detection of Proliferation in Gliomas by Positron Emission Tomography Imaging.- Transformation of Normal Astrocytes Into a Tumor Phenotype.- Mechanisms of Gliomagenesis.- Future Directions.- Cell Cycle of Encapsulated Cells.- Viral Vector Delivery to Dividing Cells.- Electrical Stimulation and Angiogenesis.- Developmental and Potential Therapeutic Aspects of Mammalian Neural Stem Cells.- Mammalian Sir2 Proteins.
Автор: Hayat Название: Tumors of the Central Nervous System, Volume 13 ISBN: 9400776012 ISBN-13(EAN): 9789400776012 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Coverage in this book includes diagnosis, intraoperative ultrasonography, cell counting, and brain metastasis. It examines a range of tumor types, including neuroblastoma, medulloblastoma, meningioma, and chordoma.
Автор: Alexander G. Karczmar; N. Chauhan; V.P. Whittaker; Название: Exploring the Vertebrate Central Cholinergic Nervous System ISBN: 148997895X ISBN-13(EAN): 9781489978950 Издательство: Springer Рейтинг: Цена: 40389.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction: History and Scope of This Book.- Cholinergic Cells and Pathways.- Metabolism of Acetylcholine: Synthesis and Turnover.- History of Research on Nicotinic and Muscarinic Cholinergic Receptors.- Muscarinic Acetylcholine Receptors in the Central Nervous System: Structure, Function, and Pharmacology.- Neuronal Nicotinic Receptors: History, Structure, and Functional Roles.- Anticholinesterases and War Gases.- Cholinergic Aspects of Growth and Development.- Central Cholinergic Nervous System and Its Correlates.- Links Between Amyloid and Tau Biology in Alzheimer's Disease and Their Cholinergic Aspects.- Envoi
Описание: This volume will cover what is known regarding the biology and treatment of CNS metastasis, including novel chapters such as the future of targeted therapies. It will begin with an overview of the natural history and risk factors for CNS metastases that will broadly cover all cancer histologies. This will be followed by 3 chapters that will cover the biology. These include: molecular biology, discussing what is known about specific genes/proteins involved in the process and model systems to study brain metastasis; the brain microenvironment, focusing on how it is different from the microenvironment of other organs of the body; and the blood-brain barrier, which includes a discussion of permeability with respect to brain metastases. A chapter on experimental imaging will cover both the biology of brain metastasis from an imaging perspective and use of imaging techniques to study brain metastases. The clinical chapters will discuss treatment options with separate chapters on surgery, chemotherapy and radiation. In addition, leptomeningeal metastasis will be given its own chapter. Finally, quality of life issues will be the concluding chapter.
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