H. Sies; A. Wendel Functions of Glutathione in Liver and Kidney 9783642671340

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Автор: H. Sies; A. Wendel
Название: Functions of Glutathione in Liver and Kidney
ISBN: 9783642671340
Издательство: Springer
Классификация:

Медицинское оборудования и методики его эксплуатации

Физиология

Науки о жизни (медико-биологические): общие вопросы

Биохимия

ISBN-10: 3642671349
Обложка/Формат: Paperback
Страницы: 214
Вес: 0.38 кг.
Дата издания: 15.11.2011
Серия: Proceedings in Life Sciences
Язык: English
Размер: 244 x 170 x 12
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: The serene phrase, Lest I forget thee, glutathione ..., coined by the Kosowers (1) to describe the state in the 1960s, must be replaced now by something like Inevitable GSH in order to characterize the current situation. The surge in interest on the ubiquitous tripeptide has been ama- zing, with publications on GSH running at rates as high as one per day, so that it seemed appropriate to convene international experts for a discussion of recent develop- ments this year. Unlike the two previous meetings in this decade held in Tlibingen in 1973 (2) and in santa Ynez in 1975 (3), the scope was restricted to Functions of Gluta- thione in Liver and Kidney. Only in this way did an in-depth discussion of the current state of knowledge in a limit- ed topic appear possible. The last couple of years have seen a fascinating pro- ductivity in the fields of (a) Regulation of the Glutathione Level in the Liver, (b) Role of y-Glutamyltransferase in Gluta- thione Turnover with emphasis on the renal enzyme, and a critical appraisal of the y-Glutamyl Cycle, (c) Hyd: roperox- ide and Disulfide Metaholism, enriched by the discovery of the nonseleniurn-dependent glutathione peroxidase activ- ity and its relation to the glutathione-S-transferases, and the participation of the 2GSH/GSSG system in redox transitions in intact organ, cells and isolated mito- chondria, and (d) a multitude of Pharmacological and Toxi- cological Aspects related to glutathione, mainly centered on the events leading to liver damage and the protective

Functions of Glutathione in Liver and Kidney, H. Sies; A. Wendel