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Glutamine Metabolism in Mammalian Tissues, D. H?ussinger; H. Sies


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Автор: D. H?ussinger; H. Sies
Название:  Glutamine Metabolism in Mammalian Tissues
ISBN: 9783642697562
Издательство: Springer
Классификация:





ISBN-10: 3642697569
Обложка/Формат: Paperback
Страницы: 300
Вес: 0.50 кг.
Дата издания: 17.11.2011
Язык: English
Размер: 244 x 170 x 17
Основная тема: Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: Glutamine is a key aminoacid for the synthesis of numerous biologic- ally important compounds in mammalian cells and is a carrier form of ammonia. The advance in knowledge on the metabolic significance of this amino acid is presented in in-depth treatments by experts in this active research field. This includes the enzymology of glutamine synthe- tase and glutaminase activities in different mammalian organs, notably liver, kidney and brain; properties of glutamine transport across bio- logical membranes; role of glutamine metabolism in the liver, with emphasis on the recent discovery of intercellular heterogeneity with respect to enzyme distribution and its functional consequences for ammonia/urea metabolism and pH regulation; renal and intestinal glutamine metabolism; cerebral glutamine/ glutamate interrelationships; skeletal muscle; role of glutamine in cell culture; and finally the clinical aspects, including the new outlook of glutamine antagonists in cancer therapy as well as the role of glutamine in hepatic coma and encephalo- pathy. Some, but not all, of the contributors to this work attended the 48th Conference of the Gesellschaft fur Biologische Chemie on glutamine metabolism held in Gottingen, W. Germany, in September 1983. This conference was supported by the Stiftung Volkswagenwerk, Dr. H. Falk Foundation, Freiburg, and the J. Pfrimmer Co., Erlangen. The abstracts of the contributions to the conference were published in Hoppe-Seylers Z. Physiol. Chem. 364,1237-125,6,1983, and this book is not intended as the proceedings of that meeting.


WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues

Автор: S.H Swerdlow
Название: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
ISBN: 9283224310 ISBN-13(EAN): 9789283224310
Издательство: WHO Press
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Цена: 9018.00 р.
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Описание: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissue is the third volume in the new WHO series on histological and genetic typing of human tumors. This authoritative, concise reference book covers the entire range of leukaemias and lymphomas. It provides an international standard for oncologists and pathologists and will serve as an indispensable guide for use in the design of studies monitoring response to therapy and clinical outcome. Diagnostic criteria, pathological features, and associated genetic alterations are described in a strictly disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, incidence, age and sex distribution, location, clinical signs and symptoms, pathology, genetics, and predictive factors.

The book, prepared by 130 authors from 22 countries, contains more than 1,000 color photographs, numerous magnetic resonance and ultrasound images, CT scans, charts, and 2,500 references.

This book is in the series commonly referred to as the "Blue Book" series.

Contributors: Dr Cem Akin, Dr Loannis Anagnostopoulos, Dr Katsuyuki Aozasa, Dr Daniel A. Arber, Dr Michele Baccarani, Dr Barbara J. Bain, Dr Giovanni Barosi, Dr Lrith Baumann, Dr Marie-Christine Bene, Dr Daniel Benharroch, Dr John M. Bennett, Dr Francoise Berger, Dr Emillo Berti, Dr Gunnar Birgegard, Dr Clara D. Bloomfield, Dr Bettina Borisch, Dr Michael J. Borowitz, Dr Richard D. Brunning, Dr Walter Burgdorf, Dr Elias Campo, Dr Daniel Catovsky, Dr Lorenzo Cerroni, Dr Ethel Cesarman, Dr Amv Chadburn, Dr John K.C. Chan, Dr Wing Chung Chan, Dr Andreas Chott, Dr Robert W. Coupland, Dr Daphne De Jong, Dr Christiane De Wolf-Peeters, Dr Martina Deckert, Dr Jan Delabie, Dr Georges Delsol, Dr Ahmet Dogan, Dr Lyn M. Duncan, Dr Kojo S.J. Elenitoba-Johnson, Dr Luis Escribano, Dr Fabio Facchetti, Dr Brunangelo Falini, Dr Judith A. Ferry, Dr Christopher D.M. Fletcher, Dr Katheryn Foucar, Dr Randy D. Gascoyne, Dr Kevin C. Gatter, Dr Norbert Gattermann, Dr Phillippe Gaulard, Dr Ulrich Germing, Dr D. Gary Gilliland, Dr Heinz Gisslinger, Dr Peter L. Greenberg, Dr Thomas M. Grogan, Dr. Karen L. Grogg, Dr Margarita Guenova, Dr Nancy Lee Harris, Dr Robert Paul Hasserjian, Dr Eva Hellstrom-Lindberg, Dr Hans-Peter Horny, Dr Peter G. Isaacson, Dr Elaine S. Jaffe, Dr Ronald Jaffe, Dr Daniel M. Jones, Dr Marshall E. Kadin, Dr Masahiro Kikuchi, Dr Hiroshi Kimura, Dr Marsha C. Kinney, Dr Phillip M. Kluin, Dr Young-Hyeh Ko, Dr Alla M. Kovrigina, Dr Laszlo Krenacs, Dr W. Michael Kuehl, Dr Jeffery L. Kutok, Dr Hans Michael Kvasnicka, Dr Robert A. Kyle, Dr Richard A. Larson, Dr Michelle M. Le Beau, Dr Lorenzo Leoncini, Dr Alan F. List, Dr Kenneth A. Maclennan, Dr William R. Macon, Dr David Y. Mason, Dr Estella Matutes, Dr Robert W. Mckenna, Dr Chris J.L.M. Meijer, Dr Junia V. Melo, Dr Dean D. Metcalfe, Dr Manuela Mollejo, Dr Peter Moller, Dr Emilli Montserrat, Dr William G. Morice, Dr Hans Konrad Muller-Hermelink, Drshigeo Nakamura, Dr Bharat N. Nathwani, Dr Charlotte M. Niemeyer, Dr Hiroko Ohgaki, Dr Kiochi Ohshima, Dr Mihaela Onciu, Dr Atillio Orazi, Dr German Ott, Dr Marco Paulli, Dr Suat-Cheng Peh, Dr Loann Peterson, Dr Tony Petrella, Dr Stefano A. Pileri, Dr Miguel A. Piris, Dr Stefania Pittaluga, Dr Maurillio Ponzoni, Dr Sibrand Poppema, Dr Anna Porwit, Dr Leticia Quintanilla-Martinez, Dr Elisabeth Ralfiaker, Dr Martine Raphael, Dr Jonathan Said, Dr Christian A. Sander, Dr Masao Seto, Dr Kevin Shannon, Dr Bruce R. Smoller, Dr Ivy Sng, Dr Dominic Spagnolo, Dr Harald Stein, Dr Christer Sundstrom, Dr Steven H. Swerdlow, Dr Ayalew Tefferi, Dr Catherine Thieblemont, Dr Jurgen Thiele, Dr Peter Valent, Dr J.H. Van Krieken, Dr James W. Vardiman, Dr Beatrice Vergier, Dr Neus Villamor, Dr Reinhard Von Wasielewski, Dr Roger A. Warnke, Dr Steven A. Webber, Dr Dennis D. Weisenburger, Dr Lawrence M. Weiss, Dr Sean J. Whittaker, Dr Rein Willemze, Dr Wyndham H. Wilson, D

Electrical Properties of Mammalian Tissues

Автор: B.J. Northover
Название: Electrical Properties of Mammalian Tissues
ISBN: 0412460505 ISBN-13(EAN): 9780412460500
Издательство: Springer
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Цена: 15672.00 р.
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Описание: This book describes the basic electrical properties of a variety of mammalian tissues in scientific terms that even a student who has had little formal training in the physics of electricity should find understandable.

Cell Death in Mammalian Ovary

Автор: V?zquez-Nin
Название: Cell Death in Mammalian Ovary
ISBN: 9400711336 ISBN-13(EAN): 9789400711334
Издательство: Springer
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Цена: 22203.00 р.
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Описание: The ovary is a suitable organ for studying the processes of cell death. Cell death was first described in the rabbit ovary (Graaffian follicles), the phenomenon being called ‘chromatolysis’. To date, it is recognized that various forms of cell death (programmed cell death, apoptosis and autophagy) are essential components of ovarian development and function. Programmed cell death is responsable for the ovarian endowment of primordial follicles around birth; in the prepuberal and adult period, apoptosis is a basic mechanism by which oocytes are eliminated by cancer therapies and environmental toxicants; in the ovarian cycle, follicular atresia and luteal regression involve follicular cell apoptosis. Finally, abnormalities in cell death processes may lead to ovarian disease such as cancer and chemoresistance. In this book, after an introductory description of various forms of cell death and of the ovary development and function in mammals, the processes of cell death in ovarian somatic cells and oocytes are described at cytological, physiological and molecular levels and analyzed in the embryonic, prepuberal and adult ovary. A complex array of molecular pathways triggered by extrinsic and intrinsic signals able tor induce or suppress cell death in the same cell, according to cell type and ovary developmental stage, emerges. Physiological interactions with the axis hypothalamus-hypophysis as well as ovarian internal functional signal are also critically reviewed to explain the abortive development of follicles before the beginning of the ovarian cycle. The book conveys information useful to the updating of biologists and physicians who are interested to the ovary biology and functions. Hopefully it should provide also clues for stimulating novel experiments in the study of cell death in the mammalian ovary still at an early stage.

Mammalian Transient Receptor Potential (TRP) Cation Channels

Автор: Bernd Nilius; Veit Flockerzi
Название: Mammalian Transient Receptor Potential (TRP) Cation Channels
ISBN: 3662512238 ISBN-13(EAN): 9783662512234
Издательство: Springer
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Цена: 49631.00 р.
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Описание: This book offers up-to-date information on the molecular and functional properties and pharmacology of mammalian Transient Receptor Potential channels, from close-up views of single protein/channels to broader principles of function and important pathologies.

The Evolution of Mammalian Characters

Автор: D. M. Kermack
Название: The Evolution of Mammalian Characters
ISBN: 1468478192 ISBN-13(EAN): 9781468478198
Издательство: Springer
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Цена: 12157.00 р.
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Описание: This book is not intended to give a full and comprehensive account of the Mesozoic mammals, and nor is it intended as a handbook for research workers studying pre-Tertiary mammals. Our account ends with the end of the Lower Cretaceous, since by that time the major characters of the mammals had become established.

Cryopreservation of Mammalian Gametes and Embryos

Автор: Zsolt Peter Nagy; Alex C. Varghese; Ashok Agarwal
Название: Cryopreservation of Mammalian Gametes and Embryos
ISBN: 1493968262 ISBN-13(EAN): 9781493968268
Издательство: Springer
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Цена: 19564.00 р.
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Описание:

Preface
Table of Contents
Contributing Authors

Part I. Introduction

1. Historical Background on Gamete and Embryo Cryopreservation
Jaffar Ali, Naif H AlHarbi, and Nafisa Ali

Part II. Basics and Advanced Biology

2. Utility of Animal Models for Human Ovarian Tissue CryopreservationSeul Ki Kim, Jung Ryeol Lee, and S.Samuel Kim
3. Current Challenges in Immature Oocyte CryopreservationRi-Cheng Chian, Yixin Xu, and Dana Keilty
4. Role of Antioxidants and Antifreeze Proteins in Cryopreservation/VitrificationSeul Ki Kim, Hye Won Youm, Jung Ryeol Lee, and Chang Suk Suh
Part III. Methodology
5. Slow Freezing of Human SpermAshok Agarwal and Eva Tvrda
6. Technology of Aseptic Cryoprotectant-free Vitrification of Human ICSI SpermatozoaVladimir Isachenko, Raul Sanchez, Peter Mallmann, Gohar Rahimi, and Evgenia Isachenko
7. Human Epididymal and Testicular Sperm CryopreservationPankaj Talwar and Sarabpreet Singh
8. Human Oocytes Slow-rate Freezing: MethodologyC. Zacа and A. Borini
9. Slow Freezing and Thawing of Human Cleavage Stage EmbryosDavid H. Edgar, Janell Archer, and Debra A. Gook
10. Human Oocyte VitrificationLaura Rienzi, Ana Cobo, and Filippo Maria Ubaldi
11. Human Embryo VitrificationJuergen Liebermann
12. Human Ovarian Tissue Slow FreezingDebra A. Gook
13. Human Ovarian Tissue VitrificationSherman Silber
14. Establishing an Oocyte Cryo Bank NetworkJames Graham, Josh Lim, and Michael Tucker
15. Development of a Nationwide Network for Ovarian Tissue CrypreservationJana Liebenthron and Markus Montag
Part IV. Advances in Cryotechnology, Research, and Animal Models
16. Directional Freezing of Ovarian Tissue and Freeze-drying of Stem Cells for Fertility PreservationAmir Arav and Natan Yehudit
17. Sterile Plate-Based Vitrification of Adherent Human Pluripotent Stem Cells and Their Derivatives Using the TWIST MethodJulia C. Neubauer, Frank Stracke, and Heiko Zimmermann
18. Vitrification: A Reliable Method for Cryopreservation of Animal EmbryosB. Singh, G. Mal, and S. K. Singla
19. Cryopreservation Effect on Genetic Function: Neonatal OutcomesVanesa Robles, Marta F. Riesco, and David G. Valcarce
20. Gavi-Automated Vitrification InstrumentTammie K. Roy, Susanna Brandi, and Teija Peura
Part V. Appendices
A. Cryotec(R) Vitrification ThawingGoral Gandhi, Masashige Kuwayama, Sakina Kagalwala, and Priyanka Pangerkar
B. Solid Surface VitrificationMohan S. Kamath and Muthukumar K.
C. Automated Vitrification of Mammalian Embryos on a Digital Microfluidic DeviceJun Liu, Derek G. Pyne, Mohamed Abdelgawad, and Yu Sun
D. Irvine Scientific(R) Vitrification SystemMatthew VerMilyea and Amber Brewer
E. Rapid-i: Closed Vitrification Device by VitrolifeMark Larman
F. Quinn's Advantage Embryo Freeze KitKiri Beilby and
Cell Death in Mammalian Ovary

Автор: Gerardo H. V?zquez-Nin; Mar?a Luisa Escobar; M. De
Название: Cell Death in Mammalian Ovary
ISBN: 9400793944 ISBN-13(EAN): 9789400793941
Издательство: Springer
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Цена: 18284.00 р.
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Описание: Following a description of various forms of cell death and of ovary development and function in mammals, cell death processes in ovarian somatic cells and oocytes are described at cytological, physiological and molecular levels, as well as at differing ages.

The Biology of Mammalian Spermatogonia

Автор: Jon M. Oatley; Michael D. Griswold
Название: The Biology of Mammalian Spermatogonia
ISBN: 149397503X ISBN-13(EAN): 9781493975037
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book provides a resource of current understandings about various aspects of the biology of spermatogonia in mammals. Considering that covering the entire gamut of all things spermatogonia is a difficult task, specific topics were selected to provide foundational information that will be useful for seasoned researchers in the field of germ cell biology as well as investigators entering the area.
Looking to the future, the editors predict that the foundational information provided in this book -- combined with the advent of new tools and budding interests in use of non-rodent mammalian models -- will produce another major advance in knowledge regarding the biology of spermatogonia over the next decade. In particular, we anticipate that the core molecular machinery driving different spermatogonial states in most, if not all, mammals will be described fully, the extrinsic signals emanating from somatic support cell populations to influence spermatogonial functions will become fully known, and the capacity to derive long-term cultures of SSCs and transplant the population to regenerate spermatogenesis and fertility will become a reality for higher order mammals.


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