Benzodiazepine Receptor Ligands, Memory and Information Processing, Ian Hindmarch; Helmut Ott

Автор: Bernd Nilius; Veit Flockerzi
Название: Mammalian Transient Receptor Potential (TRP) Cation Channels
ISBN: 364254214X ISBN-13(EAN): 9783642542145
Издательство: Springer
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Цена: 53106.00 р.
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Описание: In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field will describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.

Автор: Katharine Herrick-Davis; Graeme Milligan; Giuseppe
Название: G-Protein-Coupled Receptor Dimers
ISBN: 3319601725 ISBN-13(EAN): 9783319601724
Издательство: Springer
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Цена: 27950.00 р.
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Описание: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses.

Автор: Margaret A. Cormack; R. Glynn Owens; Michael E. De
Название: Reducing Benzodiazepine Consumption
ISBN: 0387970355 ISBN-13(EAN): 9780387970356
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Spurred by reports in 1980 detailing the ineffectiveness of long-term treatment with benzodiazepines, the authors of this volume began a study to investigate the reasons behind the addiction, quickly adopting a psychological approach to treatment.

Автор: Alexander Sigalov
Название: Multichain Immune Recognition Receptor Signaling
ISBN: 1441918876 ISBN-13(EAN): 9781441918871
Издательство: Springer
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Цена: 32004.00 р.
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Описание: This book shows how the structural similarity of MIRRs determines the general principles underlying MIRR-mediated transmembrane signaling mechanisms. In so doing, it provides the basis for existing and future therapeutic strategies targeting MIRRs.

Автор: Jeanelle Portelli; Ilse Smolders
Название: Central Functions of the Ghrelin Receptor
ISBN: 1493908227 ISBN-13(EAN): 9781493908226
Издательство: Springer
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Цена: 23757.00 р.
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Описание: The Ghrelin receptor was identified before its natural ligand ghrelin. This receptor is found both centrally and peripherally, and has been shown to affect various processes, such as food intake, gut motility, memory, glucose and lipid metabolism, cardiovascular performances, reproduction, memory, and immunological responses, amongst others. The functions of the ghrelin receptor in the central nervous system are numerous and are still being explored. In this book we specifically focus on the various roles of the ghrelin receptor in the central nervous system. In a first set of chapters, the book will focus on the discovery and the properties of this intriguing constitutively active G-protein coupled receptor, on its multiple intracellular transduction mechanisms and the various subtypes of the currently known ghrelin receptor complexes. Next, the book will elaborate on the mitochondrial mechanisms regulated by the ghrelin receptor, its role in feeding and drug addictive mechanisms, memory, sleep and arousal. The final chapters focus on the potential of this receptor as a target for the treatment of neurological disorders including Parkinson’s disease, epilepsy, anxiety and depression.

Автор: Kim Neve
Название: Functional Selectivity of G Protein-Coupled Receptor Ligands
ISBN: 1493961160 ISBN-13(EAN): 9781493961160
Издательство: Springer
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Цена: 26120.00 р.
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Описание: In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon.

Автор: Craig W. Stevens
Название: G Protein-Coupled Receptor Genetics
ISBN: 1627037780 ISBN-13(EAN): 9781627037785
Издательство: Springer
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Цена: 23757.00 р.
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Описание: G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field.

Автор: Rafael Luj?n; Francisco Ciruela
Название: Receptor and Ion Channel Detection in the Brain
ISBN: 149393063X ISBN-13(EAN): 9781493930630
Издательство: Springer
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Цена: 22203.00 р.
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Описание: Receptor and Ion Channel Detection in the Brain provides state-of-the-art and up-to-date methodological information on molecular, neuroanatomical and functional techniques that are currently used to study neurotransmitter receptors and ion channels in the brain.

Автор: R.B. Lichtner; R.N. Harkins
Название: EGF Receptor in Tumor Growth and Progression
ISBN: 3662033933 ISBN-13(EAN): 9783662033937
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Beyond cell proliferation, activation of EGF receptor by its specific ligands controls important physiological processes, such as cell differentiation, apoptosis, cell migration, and cell shape.