Realm of Tolerance, Pavol Ivanyi; M. Boiron

Автор: J.-L. Touraine; J. Traeger; H. B?tuel; J.-M. Duber
Название: Rejection and Tolerance
ISBN: 9401043450 ISBN-13(EAN): 9789401043458
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Proceedings of the 25th Conference on Transplantation and Clinical Immunology 24--26 May 1993

Автор: Olivier Morteau
Название: Oral Tolerance
ISBN: 1441934251 ISBN-13(EAN): 9781441934253
Издательство: Springer
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Цена: 32004.00 р.
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Описание: Oral Tolerance: Cellular and Molecular Basis, Clinical Aspects, and Therapeutic Potential, has been designed as a concise yet comprehensive overview of the newest fundamental and clinical advances in the field.

Автор: Ulrich Wahn
Название: Allergy, Immunity and Tolerance in Early Childhood
ISBN: 0124202268 ISBN-13(EAN): 9780124202269
Издательство: Elsevier Science
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Цена: 19875.00 р.
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Описание: . Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world. . As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the "Atopic March", along with novel ideas for potential options of prevention.

Автор: Fairchild
Название: Immunological Tolerance
ISBN: 1617376965 ISBN-13(EAN): 9781617376962
Издательство: Springer
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Цена: 25853.00 р.
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Описание: Immunological Tolerance: Methods and Protocols is a comprehensive guide to the techniques currently used for culturing and characterising the cell types responsible for imposing self-tolerance and the experimental models employed to study their function both in vitro and in vivo.

Автор: Mohammad Anwar Hossain; Mohammad Golam Mostofa; Pe
Название: Glutathione in Plant Growth, Development, and Stress Tolerance
ISBN: 3319666819 ISBN-13(EAN): 9783319666815
Издательство: Springer
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Цена: 23757.00 р.
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Описание:

Glutathione (γ-glutamyl-cysteinyl-glycine) is a ubiquitously distributed sulfurcontaining antioxidant molecule that plays key roles in the regulation of plant growth, development, and abiotic and biotic stress tolerance. It is one of the most powerful low-molecular-weight thiols, which rapidly accumulates in plant cells under stress. Recent in-depth studies on glutathione homeostasis (biosynthesis, degradation, compartmentalization, transport, and redox turnover) and the roles of glutathione in cell proliferation and environmental stress tolerance have provided new insights for plant biologists to conduct research aimed at deciphering the mechanisms associated with glutathione-mediated plant growth and stress responses, as well as to develop stress-tolerant crop plants. Glutathione has also been suggested to be a potential regulator of epigenetic modifications, playing important roles in the regulation of genes involved in the responses of plants to changing environments. The dynamic relationship between reduced glutathione (GSH) and reactive oxygen species (ROS) has been well documented, and glutathione has been shown to participate in several cell signaling and metabolic processes, involving the synthesis of protein, the transport of amino acids, DNA repair, the control of cell division, and programmed cell death. Two genes, gamma-glutamylcysteine synthetase (GSH1) and glutathione synthetase (GSH2), are involved in GSH synthesis, and genetic manipulation of these genes can modulate cellular glutathione levels. Any fluctuations in cellular GSH and oxidized glutathione (GSSG) levels have profound effects on plant growth and development, as glutathione is associated with the regulation of the cell cycle, redox signaling, enzymatic activities, defense gene expression, systemic acquired resistance, xenobiotic detoxification, and biological nitrogen fixation. Being a major constituent of the glyoxalase system and ascorbate-glutathione cycle, GSH helps to control multiple abiotic and biotic stress signaling pathways through the regulation of ROS and methylglyoxal (MG) levels. In addition, glutathione metabolism has the potential to be genetically or biochemically manipulated to develop stress-tolerant and nutritionally improved crop plants. Although significant progress has been made in investigating the multiple roles of glutathione in abiotic and biotic stress tolerance, many aspects of glutathione-mediated stress responses require additional research.

The main objective of this volume is to explore the diverse roles of glutathione in plants by providing basic, comprehensive, and in-depth molecular information for advanced students, scholars, teachers, and scientists interested in or already engaged in research that involves glutathione. Finally, this book will be a valuable resource for future glutathione-related research and can be considered as a textbook for graduate students and as a reference book for frontline researchers working on glutathione metabolism in relation to plant growth, development, stress responses, and stress tolerance.