Описание: Cancer therapy remains a challenge despite the huge changes and improvements we have made in the scientific and engineering tools that we use. Emerging Cancer Therapy explores the potential and actual uses of live bacteria or their products in the treatment of cancer.
Автор: Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642141358 ISBN-13(EAN): 9783642141355 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Автор: William McGuire Название: Current Approaches to Therapy ISBN: 1475704828 ISBN-13(EAN): 9781475704822 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: We have progressed from single-agent adjuvant chemotherapy to combined modality regimens consisting of combination chemotherapy plus im- munotherapy, plus radiotherapy, plus endocrine therapy.
Автор: Glenn Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642267882 ISBN-13(EAN): 9783642267888 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cancer Immunotherapy discusses tumor-immune interactions in several human cancers. The text proposes an integrated scheme of the impact of local immune reactions on clinical outcome, and illustrates various aspects of this complexity.
Описание: With great expectations we are all following developments in the area of breast cancer treatment using conjugates of anti-breast epithelial monoclonal antibodies which are now confirming earlier reports in affecting breast tumor control.
Автор: Kaspers Et Al Название: Innovative Leukemia and Lymphoma Therapy ISBN: 0849350832 ISBN-13(EAN): 9780849350832 Издательство: Taylor&Francis Рейтинг: Цена: 22202.00 р. Наличие на складе: Поставка под заказ.
Описание: Innovative Leukemia and Lymphoma Therapy provides a complete and up-to-date overview of the exciting new treatment modalities in leukemia and lymphoma that are being introduced in the clinic today.
Автор: Samir Khleif Название: Tumor Immunology and Cancer Vaccines ISBN: 1441954791 ISBN-13(EAN): 9781441954794 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: - Volume is divided into four sections, allowing easy navagation for researchers and practicing physicians- Text includes clinical trials- Written by leaders in the field
Описание: This volume explores the myriad of techniques and methodological approaches that are being used in breast cancer research. The authors critically evaluate of the advantages and disadvantages of current methodologies, starting with the tools available for understanding the architecture of the human breast, including its tissue and cellular composition. The volume discusses the importance of functional studies in breast cancer research, especially with the help of laser capture microdissection, which allows the separation of small amounts of tissue, as well as specific cells, for biochemical analysis. In addition, the authors address methodologies including stem cell separation, which has helped in significantly understanding their role in normal breast development, but also further the understanding of breast cancer and its therapeutic management. The use of in vitro techniques and established cell lines for mechanistic studies in chemotherapeutic approaches have been invaluable will be discussed. Imaging techniques for evaluating in vitro and in vivo behavior of normal and cancerous breast tissue will be explored, as it provides a better understanding of the physiopathology of cancer. The volume will also discuss the molecular analysis of gene function in breast cancer through the transcriptomic and epigenomic profile. More importantly, the advancement of more refined techniques in sequencing will be covered. This monograph will be a comprehensive, authoritative and timely, as it addresses the emerging approaches used in breast cancer research.
