Erythropoietin, Wolfgang Jelkmann; Mary Cotes; Andreas J. Gross
Автор: Ahmet H?ke Название: Erythropoietin and the Nervous System ISBN: 1489973834 ISBN-13(EAN): 9781489973832 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Erythropoietin (EPO) is a chemokine hormone that is widely distributed throughout the body. In addition to its traditional role as a hormone that stimulates red blood cell production, in recent years many laboratories have shown that EPO can act as a neuroprotective compound in a variety of injury paradigms in the nervous system. Past experience with relatively safety profile of this FDA-approved drug makes it an ideal candidate to take it into clinical trials for neuroprotection. We are on the verge of major clinical trials using this drug for neuroprotection in diseases ranging from stroke, to transverse myelitis to chemotherapy-induced peripheral neuropathy. This is the first book of its kind that brings together researchers from many different disciplines of neuroscience to review the current state-of-the-art in EPO and the nervous system. This book will benefit scientists and clinicians interested in neuroprotection in the broadest sense.
Описание: Proceedings of the NATO Advanced Research Workshop on Mole- cular and Cellular Aspects of Erythropoiesis held in Bad Windsheim, FRG, September 1-4, 1986
Автор: Mohammad Resa Nowrousian Название: Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology ISBN: 3709119049 ISBN-13(EAN): 9783709119044 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In its Second Edition, this book covers anemia in cancer patients, and treatment with Recombinant Human Erythropoietin (rhEPO). Expanded and updated with new chapters, it describes scientific and clinical aspects of anemia, with diagnostic and therapeutic recommendations on use of rhEPO.
Автор: Horst Pagel; Christoph Weiss; Wolfgang Jelkmann Название: Pathophysiology and Pharmacology of Erythropoietin ISBN: 3642770762 ISBN-13(EAN): 9783642770760 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: I am honored to be invited to prepare a foreword for the proceedings of the Second International Lubeck Conference on Erythropoietin (Epo). I congratulate Wolfgang Jelkmann, Horst Pagel and Christoph Weiss for their organization of an excellent program for this conference which updated all of us on the advances made in erythropoietin research during the past few years since the first conference in June of 1988. I am sure that Professor Paul Carnot, had he been present at this conference, would be very pleased and proud of the advances made in the field of erythropoietin since his and Madame DeFlandre's seminal finding in 1906 (1) that rabbits produced a humoral substance following bleeding which controls red blood cell production. The reports by Hjort in 1936 (2) and by Erslev in 1953 (3) that large volumes of plasma or serum from rabbits following a bleeding stimulus, when injected into normal donor rabbits, produced a reticulocytosis, were very significant in confirming the existence of a humoral factor which controls erythropoiesis. Reissmann's parabiotic rat experiments in 1950 (4) reawakened interest in erythropoietin when he proved that hypoxia stimulated the production of a factor which regulates red cell produc- tion. The studies of several investigators such as Jacobson et al. (5), Fisher and Birdwell (6), Kuratowska et al. (7) and Nathan et al.
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