Описание: 1 2 3 O. D. Wiestler, U. Schlege1, andJ. Schramm lInstitut flir Neuropathologie, Universitatskliniken Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany 2Neurologische Universitatsklinik, Sigmund-Freud-Str. 25, 53127 Bonn, Germany 3Neurochirurgische Universitatsklinik, Sigmund-Freud-Str. 25,53127 Bonn, Germany In contrast to various other neoplastic disorders, there has still been no dramatic progress in the treatment of gliomas. Modem microsurgical and imaging techniques have made more tumors surgically accessible and have allowed a more extensive surgical resection. However, these new developments have not improved the clinical outcome. Recently, molecular biological studies on genes and genetic loci affected in tumors of the nervous system have yielded significant new insights into pathoge- netic machanisms. Many neuro-oncologists are therefore looking forward to transla- ting molecular genetic findings into novel diagnostic and therapeutic strategies for the management of these devastating neoplasms. We have produced this volume with the intention of highlighting major developments in both molecular and clinical neuro-oncology and of stimulating the communication and cooperation between these two fields. Two major families of growth-controlling genes have emerged from the past decade of intense research on the molecular genetics of tumors: oncogenes and tumor suppressor genes. Oncogenes are characterized by their potential to stimulate the growth of susceptible cells whereas tumor suppressor genes share a growth-inhibi- ting property. A stringently controlled interplay between these two regulatory me- chanisms is required to maintain a stable composition of tissues.
Автор: Joseph A., Jr. Mauriello; Joseph C. Flanagan Название: Management of Orbital and Ocular Adnexal Tumors and Inflammations ISBN: 3662084651 ISBN-13(EAN): 9783662084656 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is designed to provide the busy ophthal- inftammation, lacrimal gland tumors and inftamma- mologist with a practieal guide to the management tion, lacrimal sac tumors and inftammation, and of lid and ocular adnexal disease.
Автор: Nigel Kirkham; Dennis W.K. Cotton; Roger C. Lallem Название: Diagnosis and Management of Melanoma in Clinical Practice ISBN: 1447119274 ISBN-13(EAN): 9781447119272 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the last decade there has been no major clinical mono-graph on this increasingly common and difficult malignancywhich is a killer of young people. The gap in the literatureis now filled by this authoritative volumewhich will beessential reading for any body involved in the study ormanagement of melanoma.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
