Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis, O.R. Hommes; G. Comi
Автор: S.H. Parvez; Peter Riederer Название: Oxidative Stress and Neuroprotection ISBN: 3709117364 ISBN-13(EAN): 9783709117361 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson’s disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson’s therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.
Описание: This book reviews the main neurobiological, neurophysiological, MRI and clinical features of the early phases of MS. Mechanisms of irreversible axonal damage and the role played by the interaction between glial and axons are highlighted.
Автор: Ian D. Duncan; Robin J M Franklin Название: Myelin Repair and Neuroprotection in Multiple Sclerosis ISBN: 1489988408 ISBN-13(EAN): 9781489988409 Издательство: Springer Рейтинг: Цена: 22201.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers the novel approach of myelin repair to restore conduction to demyelinated fibers, and to protect them against future loss, now emerging as a translational therapy for MS. Experts discuss what is needed to move toward clinical applications.
Описание: As life expectancy increases and population ages, the already enormous impact of neurodegeneration on society will become even larger without better prevention and treatment. Developing strategies to prevent degeneration of neurons and to promote a healthy nervous system is, thus, critical.
Автор: Cesario V. Borlongan; Ole Isacson; Paul R. Sanberg Название: Immunosuppressant Analogs in Neuroprotection ISBN: 1468497421 ISBN-13(EAN): 9781468497427 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An authoritative survey of the most recent scientific evidence showing how cyclosporin, FK-506, and their analogs-the neuroimmunophilins-evolved from being purely immunosuppressant "drugs" to neuroprotective "agents". The book focuses on recent preclinical evidence that demonstrates the neurotrophic/neuroprotective effects of immunosuppressants when administered alone or when combined with neural transplantation therapy in animal models of neurological disorders. It also discusses their efficacy and mechanisms of action in vitro and in vivo models of CNS disease, and provides laboratory studies with compelling clinical indications for Alzheimer's disease, Huntington's disease, stroke, traumatic brain injury, spinal cord injury, ALS, sciatic nerve injury, and drug addiction.
Автор: Nakazawa Название: Neuroprotection and Neuroregeneration for Retinal Diseases ISBN: 4431549641 ISBN-13(EAN): 9784431549642 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides the latest findings on neuroprotection and neuroregeneration as potential therapeutic strategies for various eye diseases, namely, glaucoma, age-related macular degeneration (AMD), retinal detachment, and retinitis pigmentosa.
Описание: This book reviews current progress on heat shock proteins in the brain and their implications for neurodegenerative diseases, neuroprotection, aging and control of life span. It features contributions from laboratories from major universities around the world.
Автор: I. Homma; S. Shioda Название: Breathing, Feeding, and Neuroprotection ISBN: 4431287744 ISBN-13(EAN): 9784431287742 Издательство: Springer Рейтинг: Цена: 13275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents a detailed analysis of current understanding of breathing. The book reviews research on the human brain, focusing on the recently developed EEG/dipole tracing method, as well as animal experiments. The book is a useful reference for researchers in neuroscience and related fields.
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