Описание: Next Generation Sequencing (NGS) is the latest high throughput technology to revolutionize genomic research. NGS generates massive genomic datasets that play a key role in the big data phenomenon that surrounds us today. To extract signals from high-dimensional NGS data and make valid statistical inferences and predictions, novel data analytic and statistical techniques are needed. This book contains 20 chapters written by prominent statisticians working with NGS data. The topics range from basic preprocessing and analysis with NGS data to more complex genomic applications such as copy number variation and isoform expression detection. Research statisticians who want to learn about this growing and exciting area will find this book useful. In addition, many chapters from this book could be included in graduate-level classes in statistical bioinformatics for training future biostatisticians who will be expected to deal with genomic data in basic biomedical research, genomic clinical trials and personalized medicine. About the editors: Somnath Datta is Professor and Vice Chair of Bioinformatics and Biostatistics at the University of Louisville. He is Fellow of the American Statistical Association, Fellow of the Institute of Mathematical Statistics and Elected Member of the International Statistical Institute. He has contributed to numerous research areas in Statistics, Biostatistics and Bioinformatics. Dan Nettleton is Professor and Laurence H. Baker Endowed Chair of Biological Statistics in the Department of Statistics at Iowa State University. He is Fellow of the American Statistical Association and has published research on a variety of topics in statistics, biology and bioinformatics.
Автор: Van Ooijen Название: Genetic Mapping in Experimental Populations ISBN: 1107601037 ISBN-13(EAN): 9781107601031 Издательство: Cambridge Academ Рейтинг: Цена: 4910.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This concise introduction to genetic mapping in diploid species teaches the theory behind map construction, explains the computations involved at each stage, and provides exercises and problem-solving tips. It will enable graduate students and researchers in the life sciences to employ methods effectively and to achieve more reliable results.
Автор: Terry Speed; Michael Waterman Название: Genetic Mapping and DNA Sequencing ISBN: 0387948031 ISBN-13(EAN): 9780387948034 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Statistics, mathematics and computing all play important roles in genetics mapping, physical mapping and DNA sequencing, the three key components of the human and other genome projects. This volume reviews recent progress in the area, with emphasis on the theory and application of genetic mapping.
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