Автор: Diana Boraschi Название: Immune Rebalancing: The Future of Immunosuppression ISBN: 0128033029 ISBN-13(EAN): 9780128033029 Издательство: Elsevier Science Рейтинг: Цена: 11620.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine.
Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc.
Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes
Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections
Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches
Provides information on the new strategies for drug development in this field
Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader's strategy for addressing therapeutic immune modulations
Автор: Michael Oellerich Название: Personalized Immunosuppression in Transplantation ISBN: 0128008857 ISBN-13(EAN): 9780128008850 Издательство: Elsevier Science Рейтинг: Цена: 11620.00 р. Наличие на складе: Поставка под заказ.
Описание: . Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. . The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity. . This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful.
Автор: A.W. Thomson Название: Therapeutic Immunosuppression ISBN: 940103821X ISBN-13(EAN): 9789401038218 Издательство: Springer Рейтинг: Цена: 16979.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Steven Specter; Mauro Bendinelli; Herman Friedman Название: Virus-Induced Immunosuppression ISBN: 1468455850 ISBN-13(EAN): 9781468455854 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It is now widely acknowledged that at the beginning of this century Claude von Pirquet first pointed out that a viral disease, i. e., measles, resulted in an anergy or depression of preexisting immune response, namely, delayed continuous hypersensitivity to PPD derived from Mycobacterium tuberculosis. Thereafter ob- servations that viral infections may result in immunosuppression have been recorded by many clinicians and infectious disease investigators for six or seven decades. Nevertheless, despite sporadic reports that infectious diseases caused by viruses may result in either transient or prolonged immunodepression, investigation of this phenomenon languished until the mid-1960s, when it was pointed out that a number of experimental retroviral infections of mice with tumor viruses may result in marked immunosuppression. However, it was not until the recognition of the new epidemic of acquired immunodeficiency syn- drome (AIDS) caused by the human immunodeficiency virus and related vi- ruses that acquired immunodeficiencies associated with virus infection became general knowledge among biomedical investigators as well as the lay public. A number of reviews published during the past decade or so pointed out that numerous viruses may affect humoral and cellular immune responses. Furthermore, expanding knowledge about the nature and mechanisms of both humoral and cellular immunity and pathogenesis of viral infections has pro- vided clinical and experimental models for investigating in depth how and why viruses of man and animals profoundly affect immune responses.
Автор: David Naor; Benjamin Y. Klein; Nora Tarcic; Jonath Название: Immunosuppression and Human Malignancy ISBN: 1461288460 ISBN-13(EAN): 9781461288466 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Professor Naor and his colleagues have written a book that explores another possible reason: cancer cells are recognized by the immune system-but is it possible that the consequence of recognition is inhibition of the immune system-by suppressor T cells or macrophages?
Автор: Scott A. Gruber Название: Local Immunosuppression of Organ Transplants ISBN: 3662221071 ISBN-13(EAN): 9783662221075 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For the first time a complete review of the research work done over the past 30 years by leading investigators around the world in targeting immunosuppressants to both solid-organ and cellular transplants is available in a single volume.
Автор: J.R. Salaman Название: Immunosuppressive Therapy ISBN: 9401172293 ISBN-13(EAN): 9789401172295 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Immunosuppression can be mediated by many hundreds of agents and it has been difficult to strike a balance between the `small print` of drug action in animals and the useful- ness or otherwise of drugs and other agents for inducing immunosuppression in patients.
Описание: This title provides a comprehensive and state-of-the-art summary of current and future immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies.
Описание: This title provides a comprehensive and state-of-the-art summary of current and future immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies.
Автор: Chandrasekar Pranatharthi H Название: Infections in the Immunosuppressed Patient ISBN: 0199938563 ISBN-13(EAN): 9780199938568 Издательство: Oxford Academ Рейтинг: Цена: 28116.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Infections in the Immunosuppressed Patient offers an illustrated, case-based matrix for treatment of infections across all types of immunosuppressed patients. As the challenges of managing these infections continues to evolve, this collection offers lucid, authoritative guidance to diagnosing and treating these infections effectively. Comprising 81 cases from leading experts across specialties, this collection offers a guide to both common and uncommon presentations of infections in: � Cancer patients � Solid-organ transplant recipients � Stem-cell recipients � Patients on immunosuppressive drugs � Patients with other immunosuppressive conditions Supplemented with rich color illustrations and insights from more than 100 experts, Infections in the Immunosuppressed Patient is the new benchmark reference work for treatment of these difficult cases.
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