The Brain Immune Axis and Substance Abuse, Burt M. Sharp; Toby K. Eisenstein; John J. Madden;
Автор: Isabel Varela-Nieto; Julie Ann Chowen Название: The Growth Hormone/Insulin-Like Growth Factor Axis during Development ISBN: 1461498112 ISBN-13(EAN): 9781461498117 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Insulin-like growth factor (IGF)-I is a widely expressed growth factor with diverse effects on many tissues throughout development and in adult life. The purpose of this work is to provide detailed and updated information on the role of the growth hormone (GH)-IGF axis in fetal and postnatal development, as well as its physiological functions and implications in pathology.
Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions.
Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances.
Offers a modern approach to understanding the pathology of substances of abuse, offering an evidence-based ethos for understanding the neurology of addictions
Fills an existing gap in the literature by serving as a "one-stop-shopping" synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse
Includes in each chapter: list of abbreviations, abstract, introduction, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references
Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and from the genome to whole body
Автор: Niall Hyland Название: The Gut-Brain Axis ISBN: 012802304X ISBN-13(EAN): 9780128023044 Издательство: Elsevier Science Рейтинг: Цена: 25096.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota" examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. Focuses on specific areas in which the microbiota has been implicated in gut-brain communicationExamines common mechanisms and pathways by which the microbiota may influence brain and behaviorIdentifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior
Автор: Herman Friedman; Toby K. Eisenstein; John J. Madde Название: AIDS, Drugs of Abuse, and the Neuroimmune Axis ISBN: 1461380383 ISBN-13(EAN): 9781461380382 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Third Annual Symposium held in San Diego, California, November 9-11, 1995
Автор: Eliza B. Geer Название: The Hypothalamic Pituitary Adrenal Axis in Health and Disease ISBN: 3319459481 ISBN-13(EAN): 9783319459486 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cushing?s syndrome is a rare disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function, and psychiatric disease, all of which severely reduce quality of life and life expectancy. This book reviews the role of cortisol in the human body, focusing on the effects of excess cortisol due to Cushing’s syndrome as well as the role of the HPA axis in metabolism, inflammation, and neuropsychiatric function. The volume will cover basic mechanistic data, clinical outcomes data, and novel therapies. Also discussed are everything from abnormalities of the HPA axis, to the role of the HPA axis in the development of neuropsychiatric disorders and metabolic disorders, to new definitions of Cushing’s remission and recurrence. The Hypothalamic Pituitary Adrenal Axis in Health and Disease will provide a comprehensive and multi-disciplinary review of the pathophysiology and outcomes of excess cortisol in the human body and brain as well as the role of the HPA axis in other disease states.
Автор: Rolf C. Gaillard Название: The Acth Axis: Pathogenesis, Diagnosis and Treatment ISBN: 1461351081 ISBN-13(EAN): 9781461351085 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The student of Cushing`s Disease and the HPA axis will find elucidation of the latest basic scientific advances, coupled with patient friendly guidelines for clinical diagnosis and management of an extremely challenging neuroendocrine disorder.
Автор: Herman Friedman; Thomas W. Klein; Mauro Bendinelli Название: Infectious Diseases and Substance Abuse ISBN: 1441934669 ISBN-13(EAN): 9781441934666 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The use of recreational drugs of abuse by large numbers of individuals in this country and abroad has aroused serious concerns about the consequences of this activity.
Автор: Ralph E. Tarter; Robert T. Ammerman; Peggy J. Ott Название: Handbook of Substance Abuse ISBN: 1441932976 ISBN-13(EAN): 9781441932976 Издательство: Springer Рейтинг: Цена: 26552.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and an altered neuroimmune profile. This book integrates emerging knowledge on neural-immune interactions with key discoveries in alcohol research and provides a comprehensive overview of neural-immune interactions in brain function and behavior associated with alcohol use disorders. While Neural–Immune Interaction in Brain Function and Alcohol Related Disorders focuses on neural-immune interactions in areas directly related to alcohol use disorders, it is not intended to be all inclusive. Several areas, including sleep disorders, pain, and cholinergic anti-inflammatory pathways, are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts.
Описание: This book surveys neuroimmune function, and describes antibacterial, neuroprotective and neuroregenerative properties of proline-rich polypeptides. Reviews the action of galarmin in targeting anthrax, tuberculosis, staphylococcus and other pathogens.
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