Translational Regulation of Gene Expression 2, J. Ilan
Автор: J. Ilan Название: Translational Regulation of Gene Expression ISBN: 146845367X ISBN-13(EAN): 9781468453676 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Given the accelerated growth of knowledge in the field of gene expression, it seemed timely to discuss current developments in the area of translational reg- ulation of gene expression as well as to evaluate emerging technology. Translational regulation occurs with prokaryotic as well as with eukaryotic messenger RNA (mRNA) in vivo and in vitro. In prokaryotes, through genetic manipulations and mutagenesis, the mechanisms are much better understood, as for example the mechanism of attenuation. In bacteria, different translational efficiencies for the same mRNA may vary by lOOO-fold. Translational regulation was first observed in 1966 with RNA phages of Escherichia coli by Lodish and Zinder. However, translational regulation of proteins from DNA genomes is also well described for bacteria, as for example gene 32 protein of bacteriophage T4 and E. coli ribosomal proteins. In eukaryotes, the utilization of an individual mRNA species with different efficiencies is poorly understood. For example, mRNA for ribosomal proteins is translationally regulated during Drosophila oogenesis, without any clue to the mechanism involved. It was observed that ribosomal protein mRNA during Drosophila oogenesis and embryogenesis is selectively on or off the polysomes during different developmental stages. In contrast, bacterial ribosomal protein is also translationally regulated by autogenous regulation. The mechanism is well understood and involves binding of the gene product to its transcript in competition with rRNA.
Автор: Robert Rhoads Название: miRNA Regulation of the Translational Machinery ISBN: 3642031021 ISBN-13(EAN): 9783642031021 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is dedicated to understanding how miRNAs affect translation. It includes chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs.
Автор: Abraham Название: Translational Vascular Medicine ISBN: 1447158326 ISBN-13(EAN): 9781447158325 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Translational medicine underpins vascular medicine. It is fundamental to understanding how we treat patients with vascular disease and more importantly, how to prevent it. It is the rationale for drug design and production. Vascular medicine and translational medicine will take over and become the main reason for referring patients to hospital. Therefore, hospital-based clinicians working with basic scientists need to know about translational medicine, which educates and informs them about vascular medicine and how management should be based. This book is a primer for translational vascular medicine and discusses the evolving and exciting areas of basic science applied to vascular medicine. The book is based on the third vascular biology conference held at The Royal College of Physicians in 2008. It provides a large amount of new basic and clinical information and the contributors are world leaders.
Автор: Robert Rhoads Название: miRNA Regulation of the Translational Machinery ISBN: 364226140X ISBN-13(EAN): 9783642261404 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is dedicated to understanding how miRNAs affect translation. It includes chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs.
Автор: Cecilio J. Vidal Название: Post-Translational Modifications in Health and Disease ISBN: 1461427002 ISBN-13(EAN): 9781461427001 Издательство: Springer Рейтинг: Цена: 41787.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Post-translational modifications serve many different purposes in a wide variety of cellular processes. This book provides the reader with nineteen reviews that stimulate further investigations in the proteomic field.
Описание: This book highlights major advances in researching a cell`s molecular machinery through analytical, computational, and imaging methods. It focuses on developing biophysical approaches to studying control of gene expression at the translational level.
Автор: Shashi Bala Singh; Nanduri R. Prabhakar; Srinivas Название: Translational Research in Environmental and Occupational Stress ISBN: 8132219279 ISBN-13(EAN): 9788132219279 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cutting edge technologies can propel a simple finding in basic science to a concept that can be of immense value to the society. While applying novel techniques to unravel the mysteries of biological processes, an offshoot of applied branch emerged. This field, which is now widely referred to as Translational Research utilizes basic science findings and translates these findings into innovative concepts for the benefit of mankind. This branch of science has evolved into a multidisciplinary juggernaut encompassing all known fields of science as varied as biomedicine, environment, law, economics, sociology, etc. With the ever increasing interest in this branch and the dreams and aspirations that this field can bring, basic science researchers are now taking a bold step into this new realm, merging different fields of knowledge to come up with novel inventions. This book "Translational research in environmental and occupational stress" provides and insight into the research that led to discoveries, inventions and development of novel technologies which will have a tremendous impact on the future of mankind.
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