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Hepatitis Prevention and Treatment, Joseph M. Colacino; Beverly A. Heinz


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Цена: 20962.00р.
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Автор: Joseph M. Colacino; Beverly A. Heinz
Название:  Hepatitis Prevention and Treatment
ISBN: 9783034896177
Издательство: Springer
Классификация:




ISBN-10: 3034896174
Обложка/Формат: Paperback
Страницы: 246
Вес: 0.38 кг.
Дата издания: 30.10.2012
Серия: Milestones in Drug Therapy
Язык: English
Издание: Softcover reprint of
Иллюстрации: Xi, 246 p.
Размер: 234 x 156 x 14
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание:

Chronic viral hepatitis has emerged as one of the most common causes of disease and death worldwide. Because of their unique modes of replication and intimate association with the host immune system, hepatitis B virus (HBV) and hepatitis C virus (HCV) pose challenging problems to scientists in basic and applied research as well as to clinicians engaged in disease management. Although approved antiviral therapy is available for chronic HBV, the emergence of viral resistance provides a rationale for the development of novel chemotherapeutic agents. The lack of a robust cell culture system for HCV replication and a readily accessible small-animal model of HCV infection have hampered the development of antiviral agents for HCV. Neverthe-less, new antiviral agents targeting HCV are now in preclinical and clinical development.

This monograph, providing an up-to-date overview of the field of Hepatitis Prevention and Treatment, includes contributions from internationally recognized experts in the field of viral hepatitis, and covers the current state of knowledge and practice regarding the molecular biology, immunology, biochemistry, pharmacology and clinical aspects of chronic HBV and HCV infection. The volume includes salient topics such as: the history and epidemiology of HBV and HCV; recent insights into the molecular mechanisms of viral replication; the host immune response to infection and a discussion of the use (HBV) or potential development (HCV) of vaccines; the current standard of care for chronically-infected patients; and emerging therapies and issues associated with current antiviral treatments. The latest information to researchers and clinicians actively engaged in viral hepatitis research is provided, but also sufficient background and discussion of the literature to benefit the newcomer to the field.




Hepatitis C Virus Disease / Immunobiology and Clinical Applications

Автор: Jirillo Emilio
Название: Hepatitis C Virus Disease / Immunobiology and Clinical Applications
ISBN: 0387713751 ISBN-13(EAN): 9780387713755
Издательство: Springer
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Цена: 25155.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: Innate immunity in Type C Hepatitis.- Mechanisms of Interferon Action and Resistance: Lessons learned from cell cultures studies.- Immunological Parameters Determining the Outcome of Hepatitis C Virus Infection.- The Effects of Interferon-Alpha Therapy on Immune Response and Outcome.- Microbial Components Associated with HCV Disease Interfere with Response to Interferon-alpha/Ribavarin Treatment.- IFN-induced Effector Proteins and HCV Replication.- Treatment of Chronic Hepatitis C with Various Genotypes.- IFNs in HCV infection: Biological and Clinical Considerations.- Clinical application of IFN-based therapy for HCV.- HCV therapy in difficult-to-treat patients.- Effects of IFN-alpha/Ribavirin Treatment on HCV Disease and Related Progression.    

Hepatitis B & C Managemt & Treat

Название: Hepatitis B & C Managemt & Treat
ISBN: 1841840777 ISBN-13(EAN): 9781841840772
Издательство: Taylor&Francis
Цена: 3514.00 р.
Наличие на складе: Поставка под заказ.

Описание: This text covers Hepatitis B and C, though the focus is clearly on Hepatitis C

Hepatitis B Vaccines in Clinical Practice

Автор: Ellis
Название: Hepatitis B Vaccines in Clinical Practice
ISBN: 0824787803 ISBN-13(EAN): 9780824787806
Издательство: Taylor&Francis
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Цена: 53592.00 р.
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Описание: Presents recommendations for vaccination for pre- and post-exposure prophylaxis in various suitable target populations and groups. This book: discusses serological assays in the field; examines how the vaccine was tested in international clinical trials; and, reveals how the vaccine may prevent some forms of hepatocellular carcinoma.

Hepatitis C in Developing Countries

Автор: Kamal, Sanaa M.
Название: Hepatitis C in Developing Countries
ISBN: 0128032332 ISBN-13(EAN): 9780128032336
Издательство: Elsevier Science
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Цена: 13298.00 р.
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Описание:

Hepatitis C in Developing Countries: Current and Future Challenges explores the current state of HCV in several countries, including Africa, Asia and South America. It maintains a dedicated focus on the epidemiology, clinical patterns, virologic diversity, coinfections, natural history and progression, complications, and response to standard of care (SOC) pegylated interferon and ribavirin therapy of HCV with recommendations specific to middle and low income countries. Readers will find detailed information on the burden of HCV infection from a global health and economic perspective, along with data from multicenter trials on DAAs that have enrolled patients infected with HCV non-genotype 1.


  • Features coverage on the prevention of, or inhibition of, liver fibrosis, cirrhosis, and hepatocellular carcinoma
  • Presents data from trials on patients with diverse ethnic backgrounds and those infected with genotypes 3, 4, 5, 6
  • Addresses the epidemiology, modes of transmission, socio-political aspects, genotypes, and co-infections of Hepatitis C

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