Описание: This thesis mainly describes the development of a screening process for a mirror-image library of chiral natural products. It demonstrates how, by using mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mirror process.
Автор: Ruth F. Chadwick; Darren Shickle; H.A. Ten Have; U Название: The Ethics of Genetic Screening ISBN: 9048151783 ISBN-13(EAN): 9789048151783 Издательство: Springer Рейтинг: Цена: 27951.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This collection of essays represents the work produced in the course of a three-year project funded by the Commission of the European Communities under the Biomed I programme, on the ethics of genetic screening, entitled `Genetic screening: ethical and philosophical perspectives, with special reference to multifactorial diseases`.
Автор: Jan Knippers; Klaus Nickel; Thomas Speck Название: Biomimetic Research for Architecture and Building Construction ISBN: 3319463721 ISBN-13(EAN): 9783319463728 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Поставка под заказ.
Описание: This book comprises a first survey of the Collaborative Research Center SFB-TRR 141 ‘Biological Design and Integrative Structures – Analysis, Simulation and Implementation in Architecture’, funded by the Deutsche Forschungsgemeinschaft since October 2014. The SFB-TRR 141 provides a collaborative framework for architects and engineers from the University of Stuttgart, biologists and physicists from the University of Freiburg and geoscientists and evolutionary biologists from the University of T?bingen. The programm is conceptualized as a dialogue between the disciplines and is based on the belief that that biomimetic research has the potential to lead everyone involved to new findings far beyond his individual reach. During the last few decades, computational methods have been introduced into all fields of science and technology. In architecture, they enable the geometric differentiation of building components and allow the fabrication of porous or fibre-based materials with locally adjusted physical and chemical properties. Recent developments in simulation technologies focus on multi-scale models and the interplay of mechanical phenomena at various hierarchical levels. In the natural sciences, a multitude of quantitative methods covering diverse hierarchical levels have been introduced. These advances in computational methods have opened a new era in biomimetics: local differentiation at various scales, the main feature of natural constructions, can for the first time not only be analysed, but to a certain extent also be transferred to building construction. Computational methodologies enable the direct exchange of information between fields of science that, until now, have been widely separated. As a result they lead to a new approach to biomimetic research, which, hopefully, contributes to a more sustainable development in architecture and building construction.
Автор: James E. Ambrose Название: Teacher`s Manual for Building Construction and Design ISBN: 1461365651 ISBN-13(EAN): 9781461365655 Издательство: Springer Рейтинг: Цена: 4570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This manual explores the This publication is intended for persons who are various possibilities for using the book in just planning to use my book, Building Construction about all the ways I can imagine in terms of and Design, as a basic text or reference for some teaching effort.
Автор: Ulrich Ramacher; Christoph von der Malsburg Название: On the Construction of Artificial Brains ISBN: 366250197X ISBN-13(EAN): 9783662501979 Издательство: Springer Рейтинг: Цена: 19589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This well structured, interdisciplinary and introductory book on artificial brains presents the neurocomputer of the second generation. It uses experiment, theory and implementation in a balanced new way to construct artificial brains.
Автор: Juval Portugali Название: The Construction of Cognitive Maps ISBN: 0792339495 ISBN-13(EAN): 9780792339496 Издательство: Springer Рейтинг: Цена: 31305.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aimed at researchers and students of cognitive mapping and environmental cognition, this work focuses on the cognitive processes by which one form of information is being transformed into another, and by which multiple forms of information participate in constructing cognitive maps.
Описание: Insects are great classroom study organisms. The purpose of this book is to explain how to build and use insect collecting and rearing devices and through explanations of the various techniques stimulate educators to explore the study of insects in their classrooms.
Описание: With genetic testing and screening, adults might be healthy, predisposed to an illness, probably at risk, at risk, or carriers of certain risks. Genetic testing and screening hits another dramatic note when cells and embryos are tested and subsequently altered to hit targets of perfection.
Автор: Juval Portugali Название: The Construction of Cognitive Maps ISBN: 9048146771 ISBN-13(EAN): 9789048146772 Издательство: Springer Рейтинг: Цена: 21942.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Jeremy Nicholson Название: Personalized Medicine and Population Screening ISBN: 0128003448 ISBN-13(EAN): 9780128003442 Издательство: Elsevier Science Рейтинг: Цена: 16338.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches.
In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics.
In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream.
Translates the conjunction of new surgical tools for intraoperative, real-time, metabolite evaluation and direct analysis of biofluid samples into novel options for augmented clinical decision-making
Discusses longitudinal sampling from individual patients for stratified medicine
Covers high resolution analytical spectroscopy and sophisticated computational modelling for prediction of adverse reactions in critical care scenarios, prognostic evaluation of cancer from biofluidism, and prognostic prediction of metabolism or response of patients to pharmaceutical interventions
Encapsulates recent technology options for broader population profiling considerations, in particular, the metabolome-wide association studies (MWAS) that aid the translational researcher in identifying metabolic patterns associated with disease
Foreword written by Professor Dame Sally Davies who is the Chief Medical Officer for England
Автор: Richard L Bell Название: Animal Models for Medications Screening to Treat Addiction,126 ISBN: 0128040130 ISBN-13(EAN): 9780128040133 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"Animal Models for Medications Screening to Treat Addiction," the latest volume in the "International Review of Neurobiology" series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field. Brings together information on the current state of medication development for drug addiction using animal modelsContains comprehensive descriptions of various models associated with many forms of drug addictionAdds new information for translational research in the field of drug addiction
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