Purines: Basic and Clinical Aspects, T.W. Stone; Anne Simmonds
Автор: Mathias M. Muller Название: Purine Metabolism in Man—II ISBN: 1461342252 ISBN-13(EAN): 9781461342250 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Oded Sperling Название: Purine Metabolism in Man ISBN: 1468432966 ISBN-13(EAN): 9781468432961 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Major contributions to the knowledge of normal purine metabolism in man have derived from the study of inborn errors in patients with purine disorders, specifically complete and partial hypoxanthine-guanine phosphoribosyltransferase deficiency.
Автор: Geoffrey Burnstock; James G. Dobson Jr.; Bruce T. Название: Cardiovascular Biology of Purines ISBN: 1461375630 ISBN-13(EAN): 9781461375630 Издательство: Springer Рейтинг: Цена: 41925.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Following many years when a great deal of attention was directed towards the intracellular roles of purines, there is expanding interest in the field of extracellular purinergic signalling. In this book we focus on the actions of purines in cardiovascular biology, where it is clear that they play major roles in both normal and pathophysiological conditions. Activation of different purinoceptor subtypes by purines can regulate cardiac contractility and electrical activity, modulate catecholamine-mediated responses both pre- and post-junctionally, trigger and mediate ischaemic preconditioning, cause vasodilation and vasoconstriction and enhance endothelial proliferation and apoptosis as well as inhibit platelet and neutrophil function. This book covers the cardiovascular actions mediated by the major P1 and P2 subclasses of purinoceptors and emphasizes the interactions between these two signalling systems. Cardiovascular Biology of Purines covers topics ranging from molecular and cellular to systemic and clinical. It also aims to highlight how basic advances have led to the identification of novel targets for cardiovascular therapeutic developments. We hope that our book will prove to be timely and helpful.
Автор: Anwar-Saad A. Abd-Elfattah; Andrew S. Wechsler Название: Purines and Myocardial Protection ISBN: 0792338316 ISBN-13(EAN): 9780792338314 Издательство: Springer Рейтинг: Цена: 50172.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A critical review of the most up-to-date research on purines and myocardial protection. The role of purines in reversible myocardial stunning' and irreversible (myocardial infarction) ischemic injury, ventricular arrhythmias, and ischemic preconditioning is discussed in detail, by experts. All reviews address recent and rather controversial issues on purines and myocardial protection. Mechanisms of cardioprotection of exogenous versus endogenous purines are discussed in detail. The contribution of internationally recognized experts in the field of purines and cardiovascular physiology and in myocardial protection makes this a unique and interesting book for clinicians, basic scientists and students.
Автор: Geoffrey Burnstock; James G. Dobson Jr.; Bruce T. Название: Cardiovascular Biology of Purines ISBN: 0792383346 ISBN-13(EAN): 9780792383345 Издательство: Springer Рейтинг: Цена: 43184.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focuses on the actions of purines in cardiovascular biology, where it is clear that they play major roles in both normal and pathophysiological conditions. This book covers the cardiovascular actions mediated by the major P1 and P2 subclasses of purinoceptors and emphasizes the interactions between these two signalling systems.
Автор: Kenneth A. Jacobson; John W. Daly; Vincent Mangani Название: Purines in Cellular Signaling ISBN: 1461279968 ISBN-13(EAN): 9781461279969 Издательство: Springer Рейтинг: Цена: 14673.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Chris H. De Bruyn Название: Purine Metabolism in Man-IV ISBN: 1468445553 ISBN-13(EAN): 9781468445558 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These two volumes, entitled "Purine Metabolism in Man IV" con- tain the paper presented at the "IV. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse- quences for other types of cancer.
Автор: Mathias M. Muller Название: Purine Metabolism in Man—II ISBN: 1468432877 ISBN-13(EAN): 9781468432879 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: A. Rapado Название: Purine Metabolism in Man, III ISBN: 146848561X ISBN-13(EAN): 9781468485615 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: K. Mikanagi Название: Purine and Pyrimidine Metabolism in Man VI ISBN: 1468456784 ISBN-13(EAN): 9781468456783 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: My clinical studies have been succeeded by research at the molecular level on various purine metabolic abnormalities, including not only gout but also other diseases with various symptoms of wide clinical spectra.
Описание: This publication of a symposium held on 24 th and 25 th of June 1988 in Munich th is dedicated to Nepomuk Zollner on the occasion of his 65 birthday, expressing the best wishes of the authors.
Автор: R. Angus Harkness; T.B. Elion; Nepomuk Z?llner Название: Purine and Pyrimidine Metabolism in Man VII ISBN: 1489926402 ISBN-13(EAN): 9781489926401 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These two volumes record the scientific and clinical work presented at the VIIth International and 3rd European joint symposium on purine and pyrimidine metabolism in man held at the Bournemouth International Conference Centre, Bournemouth, UK, from 30th June to 5th July 1991. The series of international meetings at three yearly intervals have previously been held initially in 1973 in Israel, then Austria, Spain, the Netherlands, USA and Japan. The European society for the Study of Purine and Pyrimidine Metabolism in Man (ESSPPM) which has its own executive and some finance first met in Switzerland in 1987, then in Germany in 1989. The steady evolution of the science in this series of meetings is intellectually satisfying; the subsequent clinical progress is emotionally and economically reassuring. As befits the position of purines and pyrimidines at the centre of biochemistry, there has been steady scientific development into molecular genetics and now onto developmental controls and biochemical pharmacology. The complexities of the immune system are being unravelled but an understanding of the human brain largely eludes us. Laboratory based scientists now predominate over those who work as clinical specialists in vii rheumatology, immunology, oncology and paediatrics. However, there continue to be major clinical objectives since large sections are concerned with major causes of death like ATP depletion, cancer and now AIDS; the laboratory work is providing clinical solutions.
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