Описание: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.
Автор: Richard M. Eglen; Mont R. Juchau; Gillian Edwards; Название: Progress in Drug Research ISBN: 303489807X ISBN-13(EAN): 9783034898072 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: From the contents: - C. Brater and M. D. Murray: The effects of NSAIDs on the kidney - G. Edwards and A. H. Weston: Latest developments in potassium channel modulator drugs - M.R. Juchau and Y. Huang: Chemical teratogenesis in humans: Biochemical and molecular mechanisms - S.P. Gupta: Studies on cardiovascular drugs - G. Polak: Antifungal chemotherapy: An everlasting battle - O. Valdenaire: New insights into the bioamine receptor family
Описание: Proceedings of a NATO ASI, held in Sant Feluide Guixols, Costa Brava, Spain, April 17--27, 1990
Автор: Zhang Название: Computer-Aided Drug Discovery ISBN: 1493935194 ISBN-13(EAN): 9781493935192 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume examines computer-aided drug discovery (CADD), a crucial component of modern drug discovery programs that is widely utilized to identity and optimize bioactive compounds for the development of new drugs. With a focus on the methods that are commonly used in the early stage of drug discovery, chapters explore computer simulation, structure prediction, conformational sampling, binding site mapping, docking and scoring, in silico screening, and fragment-based drug design. In addition to the state-of-the-art theoretical concept, this book also includes step-by-step, readily reproducible computational protocols as well as examples of various CADD strategies. The limitations and potential pitfalls of different computational methods are discussed by experts, and tips and advice for their applications are suggested.Practical and thorough, Computer-Aided Drug Discovery serves as an ideal addition to the Methods in Pharmacology and Toxicology series, guiding researchers toward their lab’s goals with this exciting and versatile technology.
Описание: Volume 36 of "Progress in Drug Research" contains 5 articles and the various indexes which facilitate its use and establish the connec- tion with the previous volumes.
Автор: J.F. Cavalla Название: Risk-Benefit Analysis in Drug Research ISBN: 9401571341 ISBN-13(EAN): 9789401571340 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since 1960, and mainly as a result of the thalidomide tragedy, governmental regulation of testing and use of new medicines has grown apace throughout the world. Both these concerns have been inflamed by the recognition of the media that all drugs make news and horror drugs make the best news of all.
Описание: Volume 42 of "Progress in Drug Research" contains seven reviews and the various indexes which facilitate its use and establish the con- nection with the previous volumes. The reviews in PDR are useful to the non-specialists, who can obtain an overview of a particular field of drug research in a rela- tively short time.
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