Alterations of Chemical Equilibrium in the Nervous System, Abel Lajtha

Автор: George Perry
Название: Alterations in the Neuronal Cytoskeleton in Alzheimer Disease
ISBN: 1461289203 ISBN-13(EAN): 9781461289203
Издательство: Springer
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Описание: Although there is a general consensus that these abnormal filaments do contain cytoskeletal elements, much debate remains regarding which cytoskeletal elements are incorporated and whether the cytoskeletal rearrangement is primary or secondary to other cellular changes.

Автор: Abel Lajtha
Название: Alterations of Metabolites in the Nervous System
ISBN: 1475767420 ISBN-13(EAN): 9781475767421
Издательство: Springer
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Описание: In neurosciences one may say, 'All roads lead to Rome. It seems as though wherever one starts, the course of investigation leads to the same major ques- tions about nervous system function and dysfunction. In thinking about what to write in this preface, it occurred to me that it might be best to deal with that with which I am most familiar and to trace to some extent my own 'road to Rome. '' As I look over my work of the last 37 years, it becomes clear to me that it can be epitomized as a search for patterns. What usually began as a single- minded devotion to in-depth analysis of one or a small number of variables always has led to questions of how the results might relate to the whole living unit, whether it is cell, tissue, or organism. For a number of years after my discovery in the vertebrate central nervous system of -y-aminobutyric acid (GABA) and the enzyme which forms it, L- glutamate decarboxylase (GAD), and the identification of GABA as a major inhibitory neurotransmitter by others, I felt that my laboratory, largely bio- chemical, was wandering in the wilderness of the complexities of the vertebrate CNS without definitively coming to terms with problems related to GABAergic transmitter functions and the roles of GABA neurons in information processing.

Автор: Abel Lajtha
Название: Chemical Architecture of the Nervous System
ISBN: 1461571561 ISBN-13(EAN): 9781461571568
Издательство: Springer
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Описание: Life, either as we think of it in the abstract in its highest sense, or life, as we think of it in terms of a compact living organism, is obviously the result of complex interaction of all of the components of the organism.