Cancer, Culture and Communication, Rhonda J. Moore; David Spiegel
Автор: Cree Название: Cancer Cell Culture ISBN: 1617790796 ISBN-13(EAN): 9781617790799 Издательство: Springer Рейтинг: Цена: 32142.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With many recent advances, cancer cell culture research is more important than ever before. This timely edition of Cancer Cell Culture: Methods and Protocols covers the basic concepts of cancer cell biology and culture while expanding upon the recent shift in cell culture methods from the generation of new cell lines to the use of primary cells. There are methods to characterize and authenticate cell lines, to isolate and develop specific types of cancer cells, and to develop new cell line models. Functional assays are provided for the evaluation of clonogenicity, cell proliferation, apoptosis, adhesion, migration, invasion, senescence, angiogenesis, and cell cycle parameters. Other methods permit the modification of cells for transfection, drug resistance, immortalization, and transfer in vivo, the co-culture of different cell types, and the detection and treatment of contamination. In this new edition, specific emphasis is placed on safe working practice for both cells and laboratory researchers. These chapters contain the information critical to success – only by good practice and quality control will the results of cancer cell culture improve. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and accessible, Cancer Cell Culture: Methods and Protocols serves as a practical guide for scientists of all backgrounds and aims to convey the appropriate sense of fascination associated with this research field.
Описание: In multicellular organisms, communication between cells involves secretion of proteins that bind to receptors on neighboring cells. While this has been well documented, another mode of intercellular communication has recently become the subject of increasing interest: the release of exosomes. In cancer, tumor exosomes are involved in various aspects of pathogenesis, including proliferation, immunosuppression, and metastasis. Given the ability of exosomes to export unneeded endogenous molecules from cells, these structures hold great potential as anticancer therapeutic agents. They are also being studied as prognostic markers for cancer.
Описание: Innovations in Social Marketing and Public Health Communication
Автор: Antonella Surbone; Matja? Zwitter; Mirjana Rajer; Название: New Challenges in Communication with Cancer Patients ISBN: 1489987495 ISBN-13(EAN): 9781489987495 Издательство: Springer Рейтинг: Цена: 30745.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The relationship between oncologists and their cancer patients is rapidly evolving. Oncologists and other cancer professionals master new anticancer and supportive treatment options, while working under increasing economic pressure and time constraints, and are often unprepared to deal with all the challenges of their new position in a therapeutic relationship with cancer patients and families. Good communication is as essential as are modern laboratory tests and sophisticated diagnostics to achieve the best clinical results. This book updates the evolution of truth-telling and communication patterns worldwide and offers insights into the recent trends and emerging challenges in communication with cancer patients and families. New Challenges in Communication with Cancer Patients is an invaluable resource to medical professionals, educators and patients in establishing a strong and effective partnership built on trust and mutual understanding.
Автор: Mustapha Kandouz Название: Intercellular Communication in Cancer ISBN: 9402404244 ISBN-13(EAN): 9789402404241 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Preface, Contributors
1- Beyond the channel: Role of connexins in regulating normal and cancerous processes in the mammary gland.
2- Connexins: Bridging the gap between the tumor microenvironment and cancer cell communication in brain tumors.
3- MicroRNA and Gap Junctions in Glioblastoma cells: Implications for cellular therapy.
4- Dynamic regulation of adherens junctions: implication in cell differentiation and tumor development.
5- Cadherin-based cell-cell adhesions: adhesion structure, signalling and computational modeling.
6- E-cadherin/catenin complex modulations in human oral cancer.
7- Tumor-derived exosomes in metastasis signaling and implications.
8- Tunneling Nanotubes: Intercellular conduits for direct cell-to-cell communication in cancer.
9- Cell-Cell Fusion, Chemotaxis and Metastasis.
10- Role of the family of Ephs and Ephrins in non-junctional cell-cell communication in cancer.
11- Computational approaches to modeling of molecular interactions in multicellular systems.
12- Contact Normalization or Escape from the Matrix.
13- Intercellular communication, the tumor microenvironment, and tumor progression.
Index
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