Автор: Ashley T. Haase; Michael B.A. Oldstone Название: In Situ Hybridization ISBN: 3642744273 ISBN-13(EAN): 9783642744273 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Leading researchers present contemporary treatment of in situ hybridization applied to current issues in animal virus pathogenesis. The genetic programs played out in these cells and the newer methods of hybridization at the electron microscopic level provide valuable insight into the complexities of virus-host interaction.
Описание: Ulrich Desselberger, Gif-sur-Yvette/Cambridge.Infection of a naive (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity).
Автор: John Playfair and Gregory Bancroft Название: Infection & Immunity Fourth Edition ISBN: 0199609500 ISBN-13(EAN): 9780199609505 Издательство: Oxford Academ Рейтинг: Цена: 9027.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Gives a perfectly balanced overview of the field, describing the key infectious agents our bodies encounter and how our immune system responds to them. It also explains how diseases are spread and what measures we can take to control this spread, from vaccination to increasing public awareness.
Автор: Mohamed Al-Rubeai Название: Antibody Expression and Production ISBN: 9400736134 ISBN-13(EAN): 9789400736139 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers generation, optimization, characterization, production and applications of antibodies, offering theoretical background and describing methods for expression of antibody in microbial and animal cell cultures and transgenic animals and plants.
Автор: G.R. Coulton; J. de Belleroche Название: In Situ Hybridization: Medical Applications ISBN: 940105326X ISBN-13(EAN): 9789401053266 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In situ hybridization has developed as a means of localizing specific DNA and RNA sequences within tissues. Complementary DNA, RNA or oligonucleotide probes, suitably labelled, are hybridized to specific DNA or RNA targets within tissues.
Автор: G.R. Coulton; J. de Belleroche Название: In Situ Hybridization: Medical Applications ISBN: 0792389891 ISBN-13(EAN): 9780792389897 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In situ hybridization has developed as a means of localizing specific DNA and RNA sequences within tissues. This book describes theoretical and practical aspects of the technology. It explains the contribution made by in situ hybridization to specific areas of medical research.
Описание: This book explores the major cytokines, such as IL-1 and IFN-?, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presenting cutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.
Автор: Yefenof Название: Innate and Adaptive Immunity in the Tumor Microenvironment ISBN: 9048177138 ISBN-13(EAN): 9789048177134 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host.
Автор: Ivan Bubanovic Название: Origin of Anti-Tumor Immunity Failure in Mammals ISBN: 1475779704 ISBN-13(EAN): 9781475779707 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The history of science has shown the majority of hypotheses to be wrong. Sharp scientific criticism and strictly controlled experimental studies reject most of the hypotheses, leaving behind only a small number of assumptions and ideas.
Автор: Kiselevsky Название: Atlas Effectors of Anti-Tumor Immunity ISBN: 9048177685 ISBN-13(EAN): 9789048177684 Издательство: Springer Рейтинг: Цена: 20896.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This illustrated Atlas is a unique scientific publication. It includes major issues of up-to-date information about immunophenotype, morphology and the function of the main effectors of anti-tumor immunity in a well presented format.
Автор: Marc Feldmann; Andrew McMichael Название: Regulation of Immune Gene Expression ISBN: 0896031047 ISBN-13(EAN): 9780896031043 Издательство: Springer Рейтинг: Цена: 32004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The immune response gene workshops that took place were based on the need to understand why certain experimental animal strains were high responders and others were low responders. Research in the ensuing years has identified the Ir gene products involved in antibody responses as the la antigens, or MHC Class II antigens.
Описание: This practical collection examines methodologies originating from the benefits of genome-wide approaches to studying epigenetics, which has opened the emerging field of epigenomics. Focusing on the areas of cancer, inflammatory and autoimmune disorders, chapters discuss three main components of the epigenome and their role in the regulation of gene expression and present a detailed method section specific to studying each component, including data analyses, troubleshooting, and feasibility in different experimental settings. The main topics are high-throughput and targeted methods for DNA methylation analysis, nucleosome position mapping, studying epigenetic effects of gut microbiota, optical imaging for detection of epigenetic aberrations in living cells, methods for microRNA, and histone code profiling. Written for the Methods in Pharmacology and Toxicology series, the book includes the kind of detail and implementation advice to encourage success in the lab.
Authoritative and easily applicable, Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases aims to provide pharmacologists, molecular biologists, bioinformaticians, and toxicologists with a vital background on epigenetics and state-of-the-art techniques in epigenomics.
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