Molecular-Genetic Mechanisms of Development, Zhores A. Medvedev
Автор: Cornel Mulhardt Название: Molecular Biology and Genomics, ISBN: 0120885468 ISBN-13(EAN): 9780120885466 Издательство: Elsevier Science Рейтинг: Цена: 6772.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.
Автор: Brown Название: Essential Molecular Biology V1 ISBN: 0199636427 ISBN-13(EAN): 9780199636426 Издательство: Oxford Academ Рейтинг: Цена: 9425.00 р. 13464.00-30% Наличие на складе: Есть (1 шт.) Описание: This text is a guide to the basic techniques needed for molecular biology. It concentrates on the preparation, purification and handling of nucleic acids.
Описание: This 1985 book expounds some of the views on which hierarchies of genes control aspects of animal development. The 1990 second edition, which is reprinted here, is an expanded and largely rewritten version of Dr de Pomerai`s successful first edition.
Описание: The section on Gene and Phenotypic Expression includes discussions of transient gene expression in the nervous system (Herschman), developmental regulation of myelin-associated genes (Gordon et al.
Автор: Russel Meints Название: Control Mechanisms in Development ISBN: 1468432575 ISBN-13(EAN): 9781468432572 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Aim And Scope Of This Book Is To Review Current Information On Human Development And Processes Of Differentiation That Have Benefited From Breakthrough Analyses In Stem Cell Biology, Elucidation Of Genome And Gene Architecture And Aspects Of Regulation Of Gene Expression, Analysis Of Signaling Systems And Transcription Factor Actions.Insights Into Actions Of Specific Genes And Their Roles In Development Have Been Gathered Through Studies In Patients With Specific Birth Defects, Including Congenital Malformations, Metabolic Defects And Functional Impairments.The Book Is Organized Into Three Sections, The First Dealing With Aspects Of Genomics, Gene Structure And Regulation, Analysis Of Signaling And Function Of Specific Organelles. The Second Section Deals With Molecular Aspects Of Development Of Specific Organs And Structures Such As, Bone, Face, Brain, Heart, Liver, Pancreas, Kidney. The Last Section Deals With Specific Malformations And Tumors That Provide Insight Into Regulation Of Growth. Environmental Factors That Impact Growth And Development Are Also Covered.
Автор: Ira Black Название: Cellular and Molecular Biology of Neuronal Development ISBN: 1461296862 ISBN-13(EAN): 9781461296867 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In Chapter 3, Weston and co-workers describe the use of monoclonal antibodies that recognize specific neuronal epitopes (including specific gangliosides) for the purpose of defining heterogeneity in the neural crest, an important model system.
Автор: Grace Y. Sun; P. Kevin Rudeen; W. Gibson Wood; Yau Название: Molecular Mechanisms of Alcohol ISBN: 146128855X ISBN-13(EAN): 9781461288558 Издательство: Springer Рейтинг: Цена: 18284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Nevertheless, the key to an effective treatment to this problem is through research into understanding the mechan- isms underlying how ethanol interacts with cells and membranes. The second section is directed to the use of cell cuI tures in ethanol research and the usefulness of cell cultures in examination of the effects of ethanol in vitro.
Автор: Marie-Francoise Chesselet Название: Molecular Mechanisms of Neurodegenerative Diseases ISBN: 1617371971 ISBN-13(EAN): 9781617371974 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The field ofneurodegenerative diseases is undergoing an unprecedented revolution. The past decade has seen the identification of new mutation mecha- nisms, such as triplet repeat expansions, and new genes causing familial forms of common neurodegenerative diseases, such as Parkinson's and Alzheimer's diseases. Cellular and animal models based on this genetic information are now available and, importantly, common mechanisms are rapidly emerging among diseases that were once considered unrelated. The field is poised for the development of new therapies based on high throughput screenings and a bet- ter understanding of the molecular and cellular mechanisms leading to neurodegeneration. Molecular Mechanisms of Neurodegenerative Diseases reviews recent progress in this exploding field. By nature, such a book cannot be all inclu- sive. It focuses on Alzheimer's, Parkinson's, and CAG triplet repeat diseases. In the first chapter, Bill Klein reviews the role of A toxicity in the patho- physiology of Alzheimer's disease. This controversial issue is further exam- ined in the context of transgenic models of Alzheimer's disease by LaFerla and colleagues. Sue Griffin and Robert Mrak, and Caleb Finch and collabora- tors, then examine the role of glial cells and inflammation in Alzheimer's disease; a review of the role of proteolysis in the generation of abnormal pro- tein fragments by Hook and Mende-Mueller follows. Therapeutic opportuni- ties offered by a better understanding of Alzheimer's disease pathophysiology are examined by Perry Molinoff and his colleagues at Bristol-Myers Squibb.
Автор: Zhao-Wen Wang Название: Molecular Mechanisms of Neurotransmitter Release ISBN: 1627038841 ISBN-13(EAN): 9781627038843 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release.
Автор: Craig Nancy Название: Molecular Biology Principles of Genome Function ISBN: 0199658579 ISBN-13(EAN): 9780199658572 Издательство: Oxford Academ Рейтинг: Цена: 9186.00 р. Наличие на складе: Поставка под заказ.
Описание: A fresh, distinctive approach to the teaching of molecular biology. With its focus on key principles, its emphasis on the commonalities that exist between the three kingdoms of life, and its integrated coverage of experimental methods and approaches, Molecular Biology is the perfect companion to any molecular biology course.
Описание: This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
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