Описание: Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of expression and function of receptors, channels and transporters and their interrelationships contribute to the pathogenesis of pulmonary vascular disease; and iii) the therapeutic opportunities that may be revealed by enhancing our understanding of this area. The overall goal was to explore the mechanisms by which specific receptors, channels and transporters contribute to pulmonary vascular function in both health and disease, and how this knowledge may lead to novel interventions in lung dysplasia, pulmonary edema, lung injury, and pulmonary and systemic hypertension to reduce and prevent death from lung disease. Membrane Receptors, Channels and Transporters in Pulmonary Circulation is divided into six parts. Part 1 (Ion Channels in the Pulmonary Vasculature: Basics and New Findings) is designated for basic knowledge and recent findings in the research field of ion channels in pulmonary circulation. There are five chapters in Part I discussing the function, expression, distribution and regulation of various ion channels present in pulmonary vascular smooth muscle cells and how these channels are integrated to regulate intracellular Ca2+ and cell functions. Part II (TRP Channels in the Pulmonary Vasculature: Basics and New Findings) is composed of five chapters that are exclusively designed to discuss the role of a recently identified family of cation channels, transient receptor potential (TRP) channels, in the regulation of pulmonary vascular tone and arterial structure. Part III (Pathogenic Role of Ion Channels in Pulmonary Vascular Disease) includes four chapters that discuss how abnormal function and expression of various ion channels contribute to changes in cell functions and the development of pulmonary hypertension. Part IV (Receptors and Signaling Cascades in Pulmonary Arterial Hypertension) consists of five chapters devoted to the role of bone morphogenetic protein receptors, Notch receptors, serotonin receptors, Rho kinase and vascular endothelial growth factor receptors in the development of pulmonary arterial hypertension. Part V (Receptors and Transporters: Role in Cell Function and Hypoxic Pulmonary Vasoconstriction) includes four chapters designed to illustrate the potential mechanisms involved in oxygen sensing and hypoxia-induced pulmonary vasoconstriction and hypertension. Part VI (Targeting Ion Channels and Membrane Receptors in Developing Novel Therapeutic Approaches for Pulmonary Vascular Disease) consists five chapters which discuss the translational research involving on membrane receptors, channels and transporters, including their potential as novel drug targets. We hope that Membrane Receptors, Channels and Transporters in Pulmonary Circulation will allow readers to foster new concepts and new collaborations and cooperations among investigators so as to further understand the role of receptors, channels and transporters in lung pathophysiology. The ultimate goal is to identify new mechanisms of disease, as well as new therapeutic targets for pulmonary vascular diseases. An additional outcome should be enhanced understanding of the role of these entities in systemic vascular pathophysiology, since the conference will include researchers and clinicians with interests in both pulmonary and systemic circulations.
This SpringerBrief presents radio resource allocation schemes for buffer-aided communications systems over fading channels under statistical delay constraints in terms of upper-bounded average delay or delay-outage probability.
This Brief starts by considering a source-destination communications link with data arriving at the source transmission buffer. The first scenario, the joint optimal data admission control and power allocation problem for throughput maximization is considered, where the source is assumed to have a maximum power and an average delay constraints. The second scenario, optimal power allocation problems for energy harvesting (EH) communications systems under average delay or delay-outage constraints are explored, where the EH source harvests random amounts of energy from renewable energy sources, and stores the harvested energy in a battery during data transmission. Online resource allocation algorithms are developed when the statistical knowledge of the random channel fading, data arrivals, EH processes governing the system dynamics is unknown a-priori.
This Brief continues with a source-relay-destination communications link with buffers available at both source and relay, as part of a multi-hop network. Optimal resource allocation schemes for this 3-node relaying system to maximize its effective capacity under a delay-outage constraint are proposed, with special emphasis on relay roles: Half-duplex (HD) or full-duplex (FD) relay operation. With HD relay, the adaptive link selection relaying problem jointly with both fixed and adaptive power allocation schemes is investigated. Within each transmission frame, either the source-relay link or the relay-destination link is selected to be active depending on the channel conditions. With FD relay under the presence of non-zero residual self-interference (SI).
This Brief also presents source and relay power allocation schemes for both cases of available knowledge of the channel state information at transmitter (CSIT): instantaneous or statistical. Professional and researchers working in this related field and advanced-level students in electrical or computer engineering will find the content valuable as a reference.
Автор: Satya Prakash Gupta Название: Ion Channels and Their Inhibitors ISBN: 364244282X ISBN-13(EAN): 9783642442827 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The present book compiles important chapters authored by eminent workers in the field to cover important recent advances in the studies of the structure and functions of ion channels and their inhibitors, such as sodium ion, potassium ion, chloride ion, calcium ion channel inhibitors.
Автор: Ivan Djordjevic; William Ryan; Bane Vasic Название: Coding for Optical Channels ISBN: 1489983236 ISBN-13(EAN): 9781489983237 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This unique book provides a coherent and comprehensive introduction to the fundamentals of optical communications, signal processing and coding for optical channels. It is the first to integrate the fundamentals of coding theory and optical communication.
Автор: Ivan Djordjevic; William Ryan; Bane Vasic Название: Coding for Optical Channels ISBN: 1441955682 ISBN-13(EAN): 9781441955685 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This unique book provides a coherent and comprehensive introduction to the fundamentals of optical communications, signal processing and coding for optical channels. It is the first to integrate the fundamentals of coding theory and optical communication.
Описание: This book uses modern linear and nonlinear econometric methods to characterize how shocks to the yield of risky fixed income securities, such as sub-prime asset-backed or low-credit rating sovereign bonds, are transmitted to the yields in other markets.
Автор: Boris Martinac Название: Sensing with Ion Channels ISBN: 3662500671 ISBN-13(EAN): 9783662500675 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: All living cells are able to detect and translate environmental stimuli into biologically meaningful signals. Sensations of touch, hearing, sight, taste, smell or pain are essential to the survival of all living organisms. The importance of sensory input for the existence of life thus justifies the effort made to understand its molecular origins. Sensing with Ion Channels focuses on ion channels as key molecules enabling biological systems to sense and process the physical and chemical stimuli that act upon cells in their living environment. Its aim is to serve as a reference to ion channel specialists and as a source of new information to non specialists who want to learn about the structural and functional diversity of ion channels and their role in sensory physiology.
Автор: Franti?ek Balu?ka; Dieter Volkmann; Peter W. Barlo Название: Cell-Cell Channels ISBN: 1493901214 ISBN-13(EAN): 9781493901210 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: he biological sciences are dominated by the idea that cells are the functionally autonomous, physically separated, discrete units of life. TThis concept was propounded in the 19th century by discoveries of the cellular structuring of both plants and animals. Moreover, the ap parent autonomy of unicellular eukaryotes, as well as the cellular basis of the mammalian brain (an organ whose anatomy for a long while defied attempts to validate the idea of the cellular nature of its neurons), seemed to provide the final conclusive evidence for the completeness of *cell theory', a theory which has persisted in an almost dogmatic form up to the present day. However, it is very obvious that there are numerous observations which indicate that it is not the cells which serve as the basic units of biological life but that this property falls to some other, subcellular assemblage. To deal with this intricate problem concerning the fundamental unit of living matter, we proposed the so-called Cell Body concept which, in fact, devel ops an exceedingly original idea proposed by Julius Sachs at the end of the 19th century. In the case of eukaryotic cells, DNA-enriched nuclei are intimately associated with a microtubular cytoskeleton. In this configuration—as a Cell Body—these two items comprise the fundamental functional and struc tural unit of eukaryotic living matter. The Cell Body seems to be inherent to all cells in all organisms.
Описание: The author also reports on two platforms-magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria-that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations.
Автор: Saied Muhammed Hassan Darwish; Naveed Ahmed; Abdul Название: Laser Beam Micro-milling of Micro-channels in Aerospace Alloys ISBN: 9811036012 ISBN-13(EAN): 9789811036019 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offering guidelines on the micro-channel fabrications through Nd:YAG laser beam micro-milling, this book also shows how the laser beam micro-milling behaves in operating under water, and explores what are the pros and cons of this hybrid technique. It includes predictive mathematical models, and considers three important aerospace alloys.
Автор: Eugene G. Morozov; Alexander N. Demidov; Roman Y. Название: Abyssal Channels in the Atlantic Ocean ISBN: 9400790279 ISBN-13(EAN): 9789400790278 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is dedicated to the study of the structure, as well as the transport, of deep and bottom waters through underwater channels in the Atlantic Ocean. The study is based on recent observations, analysis of historical data, and a literature review.
Автор: Show-Ling Shyng; Francis I. Valiyaveetil; Matt Who Название: Potassium Channels ISBN: 1493973614 ISBN-13(EAN): 9781493973613 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides readers with the latest techniques and approaches used to study K+ channels.
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