Immunopharmacology in Autoimmune Diseases and Transplantation, L. Endresen; ?. F?rre; H.E. Rugstad

Автор: J?rgen Drews
Название: Immunopharmacology
ISBN: 3642755631 ISBN-13(EAN): 9783642755637
Издательство: Springer
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Описание: Immunopharmacology is defined as that part of pharmacology that deals with drugs acting on the immune system and, in addition, with the pharmacological actions of substances derived from the immune system.

Автор: G. Mathe; F. M. Muggia
Название: Cancer Chemo- and Immunopharmacology
ISBN: 3642814905 ISBN-13(EAN): 9783642814907
Издательство: Springer
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Описание: Local treatment cures about 30 to 40% of cancers, this proportion depending on the follow-up required to establish it. This means that 60 to 70% of the malignant neoplasias are disseminated either perceptibly (leukemias, visible metas- tases) or imperceptibly, forming a 'minimal imperceptible disease', which local treatment leaves, whether it consists of surgery, radiotherapy, or surgery plus radiotherapy. When the neoplastic tissue is voluminous enough to be per- ceptible, cures can be obtained with chemotherapy or chemo- immunotherapy. When the neoplastic disease is imperceptible, made up of micrometastases, it apparently can be cured by systemic postsurgical chemotherapy, immunotherapy, or chemoimmunotherapy. Hence there is the need for intensive development of these medical therapies which are applied by the medical oncol- ogist and, at present, consist of chemotherapy, immuno- therapy, or chemoimmunotherapy. These medical thera- peutics can only grow with scientific development, the main weapon of which is experimental and clinical pharmacology. These volumes report the communications presented at the 1979 EORTC Annual Plenary Session on Cancer Chemo- and Immunopharmacology.

Автор: Ian R. Mackay
Название: The Autoimmune Diseases,
ISBN: 0123849292 ISBN-13(EAN): 9780123849298
Издательство: Elsevier Science
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Описание: Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors.

Автор: L. Endresen; ?. F?rre; H.E. Rugstad
Название: Immunopharmacology in Autoimmune Diseases and Transplantation
ISBN: 0306439948 ISBN-13(EAN): 9780306439940
Издательство: Springer
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Описание: The specific disease section also covers rare situations, fluctuations in disease patterns, and subgroups of patients and immunophar- macological treatment in these situations.

Автор: Khan
Название: Immunopharmacology
ISBN: 3319302728 ISBN-13(EAN): 9783319302720
Издательство: Springer
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Описание: The concept of immunotherapy was in infancy when the first edition was written; since then, major advances have been made, not only with several prominent clinical trials, but also with the approval of cell-based therapy by the FDA for the treatment of cancer in 2010. These events resulted in a gradually narrowing gap between early scientific knowledge and the late development of immune-based therapies. Consequently, the significance and magnitude of these advances warranted a revision of this contribution; this revised edition will provide a deeper understanding of the recent advances and discoveries related to the function of the immune response and their applications in the development of novel therapies to treat human diseases. Some of the key discoveries during the past five years include: the identification of the new subsets of helper T cells; new cytokines and their networks; and novel signal transduction mechanisms. For example, the identification of TH17 subset of helper T cells, in addition to TH1 and TH2 cells, not only advanced our understanding of the function of the basic immune response, but also raised our awareness of the possible etiology and pathogenesis of diseases such as allergy, asthma, rheumatoid arthritis, and other auto-immune/immune system based diseases. The newly identified powerful cytokine networks, that regulate both innate and acquired immune responses, emerged as a result of the finding of new cell types such as innate lymphoid cells and iNKT. Identification of the novel cytokines and their networks has advanced our knowledge of the mechanisms involved in the maintenance of tissue homeostasis, including inflammation and tissue repair during stress and injury. The development of HIV vaccines has also seen dramatic changes over the last few years. There has been a shift from a sole focus on T cell vaccines to a holistic approach that pertains to the induction of both humoral and cellular elements. This entails the induction of antibodies – both binding and neutralizing – to prevent infection. The cellular vaccination produces a safety net of CD8+ T-cell responses to suppress the replication of the virus in the infected patients, and both of the effector arms are aided by helper T cells. From the perspective of clinical applications, significant advances have also been made in: oral immunotherapy for allergic disease, the possible treatment of HIV infection, the development of new monoclonal antibodies and their fragments to treat human diseases, and immune cell based therapies for cancer.

Автор: Manzoor M. Khan
Название: Immunopharmacology
ISBN: 1489990372 ISBN-13(EAN): 9781489990372
Издательство: Springer
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Описание: Immunopharmacology is the area of biomedical science that concerns the pharmacological approach to the immune response in physiological and pathological events. It`s also the reason we`re able to treat so many more diseases than ever before. This book explains it all.

Автор: G. Mathe; F. M. Muggia
Название: Cancer Chemo- and Immunopharmacology
ISBN: 364281493X ISBN-13(EAN): 9783642814938
Издательство: Springer
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Автор: J. Hadden
Название: Immunopharmacology
ISBN: 1461572517 ISBN-13(EAN): 9781461572510
Издательство: Springer
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Описание: With this surging new information about the immune system comes the possi- bility of developing a pharmacology which can modulate and control immunologic functions. , the complement system and kinin-kallikrein system, and (4) utilization, modulation, and inhibition of the galaxy of molecules generated by T lymphocytes, the lymphokines.

Автор: A. Szentivanyi; Herman Friedman
Название: Immunobiology and Immunopharmacology of Bacterial Endotoxins
ISBN: 1461293197 ISBN-13(EAN): 9781461293194
Издательство: Springer
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Описание: It became widely accepted that during infections with many gram negative organisms the fever occurring in patients, as well as many of the untoward pathophysiological effects of the infections, seemed to be due to the endotoxin the bacteria contained or released.

Автор: J.W. Hadden; A. Szentivanyi
Название: Immunopharmacology Reviews Volume 2
ISBN: 1461380103 ISBN-13(EAN): 9781461380108
Издательство: Springer
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Описание: As the editors say in their preface, `we have intended these reviews to be the best by the best`-they make this point very convincingly.` -ASM News, from a review of Volume 1 This series continues to present the most current findings in the field of immune manipulation.

Автор: J.W. Hadden; A. Szentivanyi
Название: Immunopharmacology Reviews
ISBN: 1461572541 ISBN-13(EAN): 9781461572541
Издательство: Springer
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Описание: Advances in the field of immunology have made it apparent that the immune system, like other organ systems, declines in its function as a result of aging, viral infections like AIDS, and other immunotoxic influences, giving rise to secondary immunodeficiency.