Описание: This book presents the current state of knowledge on the origin and differentiation of cell lines involved in the development of the vertebrate male and female gonads with particular emphasis on the mouse. It also discusses the processes leading to the testis- and ovary-specific structures and functions.The individual chapters review the origin and differentiation of the somatic cells of the genital ridges; the formation and migration of primordial germ cells in mouse and man; the gonadal supporting cell lineage and mammalian sex determination; differentiation of Sertoli and granulosa cells; mesonephric cell migration into the gonads and vascularization; origin and differentiation of androgen-producing cells in the gonads; germ cell commitment to the oogenic versus spermatogenic pathway and the role of retinoic acid; ovarian folliculogenesis; control of oocyte growth and development by intercellular communication within the follicular niche; biology of the Sertoli cell in the fetal, pubertal and adult mammalian testis; mechanisms regulating spermatogonial differentiation; stem cells in mammalian gonads; the role of microRNAs in cell differentiation during gonad development; human sex development and its disorders; as well as methods for the study of gonadal development.
Автор: Henry J. Leese; Daniel R. Brison Название: Cell Signaling During Mammalian Early Embryo Development ISBN: 1493924796 ISBN-13(EAN): 9781493924790 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.
Автор: John G. Monroe; Ellen Rothenberg Название: Molecular Biology of B-Cell and T-Cell Development ISBN: 1617370657 ISBN-13(EAN): 9781617370656 Издательство: Springer Рейтинг: Цена: 44582.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Despite the tremendous diversity of the cells of the hematopoietic system, they are all derived from common precursor cells that are generated in the fetus and persist into adult life. However, new technologies allow increasingly elegant and informative studies in mammalian systems, particularly for cells of the hematopoietic system.
Название: Cell cycle control and plant development ISBN: 1405150432 ISBN-13(EAN): 9781405150439 Издательство: Wiley Рейтинг: Цена: 30405.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The cell cycle in plants consists of an ordered set of events, including DNA replication and mitosis, that culminates in cell division. As cell division is a fundamental part of a plant`s existence and the basis for tissue repair, development and growth, a full understanding of all aspects of this process is of pivotal importance.
Автор: Tim Schedl Название: Germ Cell Development in C. elegans ISBN: 1489993533 ISBN-13(EAN): 9781489993533 Издательство: Springer Рейтинг: Цена: 26120.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes as well as drawing comparisons with other organisms.
Автор: M.I. Greene; T. Hamaoka Название: Development and Recognition of the Transformed Cell ISBN: 1461290708 ISBN-13(EAN): 9781461290704 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The study of the phenotypic and genetic features that characterize the malignant cell is a rapidly growing and changing field. Clearly new insights into the processes involved in normal and abnormal cell growth will facilitate our understanding of events relevant to cancer and cellular differentiation.
Автор: Isabelle Godin; Ana Cumano Название: Hematopoietic Stem Cell Development ISBN: 1489973850 ISBN-13(EAN): 9781489973856 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Hematopoietic Stem Cells brings together articles covering the biology of hematopoietic stem cells during embryonic development, reporting particular aspects of fly, fish, avian and mammalian models. Thus, this book allows a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing the conserved trends in development. This book culminates with state-of –the art knowledge on hematopoietic development in human species and discussions of the most recent breakthroughs with relevance to both researchers and clinicians.
Автор: Jacek Z. Kubiak Название: Cell Cycle in Development ISBN: 3642268544 ISBN-13(EAN): 9783642268540 Издательство: Springer Рейтинг: Цена: 36570.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book thoroughly examines current understanding of processes accompanying embryonic transitions, in which cell cycle machinery is implicated. The authors explain numerous questions of how the basic cell cycle events are controlled at the cellular level.
Автор: Wolpert, Lewis; Tickle, Cheryll Название: Principles of Development ISBN: 0199549079 ISBN-13(EAN): 9780199549078 Издательство: Oxford Academ Рейтинг: Цена: 6968.00 р. Наличие на складе: Поставка под заказ.
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