Автор: Klostermeier Dagmar Название: RNA Structure and Folding ISBN: 3110284596 ISBN-13(EAN): 9783110284591 Издательство: Walter de Gruyter Рейтинг: Цена: 26024.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: While structure-function relationships of proteins have been studied for a long time, structural studies of RNA face additional challenges. Nevertheless, with the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. This volume provides an introduction into techniques to assess structure and folding of RNA. Each chapter explains the theoretical background of one technique, and illustrates possibilities and limitations in selected application examples.
Автор: Rick Russell Название: Biophysics of RNA Folding ISBN: 1489988947 ISBN-13(EAN): 9781489988942 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume, written by experts in the field, discusses the current understanding of the biophysical principles that govern RNA folding, with featured RNAs including the ribosomal RNAs, viral RNAs, and self-splicing introns. In addition to the fundamental features of RNA folding, the central experimental and computational approaches in the field are presented with an emphasis on their individual strengths and limitations, and how they can be combined to be more powerful than any method alone; these approaches include NMR, single molecule fluorescence, site-directed spin labeling, structure mapping, comparative sequence analysis, graph theory, course-grained 3D modeling, and more. This volume will be of interest to professional researchers and advanced students entering the field of RNA folding.
Описание: Starts out by presenting the evidence for hydrophilic interactions in biochemical processes and then goes on to describe the applications of the hydrophilic interactions in these processes, specifically protein folding, protein association, self assembly and molecular recognition.
Автор: Ben-Naim Arieh Название: Myths And Verities In Protein Folding Theories ISBN: 9814725994 ISBN-13(EAN): 9789814725996 Издательство: World Scientific Publishing Рейтинг: Цена: 4435.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book tells the story of a whole field of research which went disastrously wrong in many different directions when the wrong tools were used and the wrong targets aimed at, to solve a problem.
It all started from the misinterpretation of Schellman's experiments which were carried out in the mid-1950s, and which were later encapsulated by the so-called "Hydrogen-bond inventory argument." As a result, hydrogen bonding was ignored in protein folding; along with that a whole repertoire of other possible hydrophilic effects were not even considered. Against this background the hydrophobic effects, as suggested by Kauzmann, became the single most important effects in protein folding.
In addition, as a result of the misinterpretation of Anfinsen's hypothesis, as well as misunderstanding of the Second Law, people made futile attempts to search for the structure of proteins in the global minimum of either the Energy, or the Gibbs Energy Landscape.
Описание: They are key components of a protein quality machinery in the cell which insures that the folding process of any newly-synthesized polypeptide chain results in the formation of a properly folded protein and that the folded protein is maintained in an active conformation throughout its functional lifetime.
Описание: This unique volume reviews the beautiful architectures and varying mechanical actions of the set of specialized cellular proteins called molecular chaperones, which provide essential kinetic assistance to processes of protein folding and unfolding in the cell.
Автор: Judit Ov?di; Ferenc Orosz Название: Protein folding and misfolding: neurodegenerative diseases ISBN: 9048181275 ISBN-13(EAN): 9789048181278 Издательство: Springer Рейтинг: Цена: 23508.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Offering all the latest in the study of neurodegenerative diseases, this book reviews the molecular events initiated by unfolded or misfolded proteins leading to conformational human diseases, especially those found in Parkinson`s and Alzheimer`s diseases.
Автор: Ben-Naim Arieh Название: Myths And Verities In Protein Folding Theories ISBN: 9814725986 ISBN-13(EAN): 9789814725989 Издательство: World Scientific Publishing Рейтинг: Цена: 8870.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book tells the story of a whole field of research which went disastrously wrong in many different directions when the wrong tools were used and the wrong targets aimed at, to solve a problem.
It all started from the misinterpretation of Schellman's experiments which were carried out in the mid-1950s, and which were later encapsulated by the so-called "Hydrogen-bond inventory argument." As a result, hydrogen bonding was ignored in protein folding; along with that a whole repertoire of other possible hydrophilic effects were not even considered. Against this background the hydrophobic effects, as suggested by Kauzmann, became the single most important effects in protein folding.
In addition, as a result of the misinterpretation of Anfinsen's hypothesis, as well as misunderstanding of the Second Law, people made futile attempts to search for the structure of proteins in the global minimum of either the Energy, or the Gibbs Energy Landscape.
Описание: Starts out by presenting the evidence for hydrophilic interactions in biochemical processes and then goes on to describe the applications of the hydrophilic interactions in these processes, specifically protein folding, protein association, self assembly and molecular recognition.
Автор: Andreas Wyttenbach; Vincent O`Connor Название: Folding for the Synapse ISBN: 1489982221 ISBN-13(EAN): 9781489982223 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book addresses the current view on how protein folding and misfolding, controlled by molecular chaperones, contribute to synapse function and dysfunction. Examples of the biological relevance of further chaperone functions are included.
Название: Rna interference ISBN: 3540751564 ISBN-13(EAN): 9783540751564 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the last few years the major effect that RNAi has had in invertebrate systems is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. Through the introduction of RNAi, mammalian systems have finally gained admittance to the pantheon of model genetic systems.
Автор: Sattler Название: RNA Metabolism in Neurodegenerative Diseases ISBN: 3319896881 ISBN-13(EAN): 9783319896885 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
