Автор: Leon Rosenberg Название: Human Genes and Genomes, ISBN: 0123852129 ISBN-13(EAN): 9780123852120 Издательство: Elsevier Science Рейтинг: Цена: 8134.00 р. 11620.00-30% Наличие на складе: Есть (1 шт.) Описание: Presents the study of genes and genomics that explores all aspects of the life with relevance in the lab, in the doctor`s office, in the courtroom and even in social relationships. This book communicates the importance of genes and genomics studies in all aspects of life.
Автор: Dennis Название: The Human Genome.2001 ISBN: 0333971434 ISBN-13(EAN): 9780333971437 Издательство: Palgrave Рейтинг: Цена: 3538.00 р. Наличие на складе: Нет в наличии.
Описание: The sequencing of the human genome has been hailed as the most ground breaking scientific event of the new century. It offers the exciting prospect of fresh insights into our collective history, our shared identity and our individuality, and opens up important possibilities for the identification, treatment and prevention of disease. Not since Crick and Watson's seminal paper on the structure of DNA has a scientific publication been greeted with so much public expectation for a new understanding of the basis of life itself. In this illustrated account, written and compiled by Carina Dennis and Richard Gallagher of "Nature", thenome project is made accessible for a general readership. It offers an introduction to the basic biology and techniques, a guide to the main players and events in the history of genetic science, and a range of viewpoints on its impact and reception around the world, in addition to the full text of the research paper itself.
Автор: Ravindranath Duggirala; Laura Almasy; Sarah Willia Название: Genome Mapping and Genomics in Human and Non-Human Primates ISBN: 3662518392 ISBN-13(EAN): 9783662518397 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The Utility of Genomics for Studying Primate Biology.- The Human Genome Project: Where Are We Now and Where Are We Going?.- Linkage Mapping: Localizing the Genes that Shape Human Variation.- Association Studies to Map Genes for Disease-Related Traits in Humans.- Gene Expression Studies and Complex Diseases.- Copy Number Variations and Chronic Diseases.- Applications of Genomic Methods to Studies of Wild Primate Populations.- Comparative Genomics: Tools for Study of Complex Diseases.- Genetic Structure and Its Implications for Genetic Epidemiology: Aleutian Island Populations.- Mapping Genes in Isolated Populations: Lessons from the Old Order Amish.- Genetics of Cardiovascular Disease in Minority Populations.- Mapping of Susceptibility Genes for Obesity, Type 2 Diabetes, and the Metabolic Syndrome in Human Populations.- Genetic Influence on the Human Brain.- Variation, Genetics, and Evolution of the Primate Craniofacial Complex.- Genetic Influences on Behavior in Nonhuman Primates.- Genomic Studies of Human Populations: Re-sequencing Approaches to the Identification of Human Quantitative Loci.
Автор: Nasheuer Название: Genome Stability and Human Diseases ISBN: 9400731256 ISBN-13(EAN): 9789400731257 Издательство: Springer Рейтинг: Цена: 28732.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research.
Автор: Nasheuer Название: Genome Stability and Human Diseases ISBN: 9048134706 ISBN-13(EAN): 9789048134700 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research.
Автор: Ravindranath Duggirala; Laura Almasy; Sarah Willia Название: Genome Mapping and Genomics in Human and Non-Human Primates ISBN: 3662463059 ISBN-13(EAN): 9783662463055 Издательство: Springer Рейтинг: Цена: 25155.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.
Автор: Avril D. Woodhead; Benjamin J. Barnhart Название: Biotechnology and the Human Genome ISBN: 1468455494 ISBN-13(EAN): 9781468455496 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is based on the proceedings of the Science Writers Workshop on "Biotechnology and the Human Genome: Innovations and Impacts" held at the Brookhaven National Laboratory on September 14-16, 1987.
Автор: Thomas F. Lee Название: The Human Genome Project ISBN: 0306439654 ISBN-13(EAN): 9780306439650 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"This is a study of genetic mapping. The first six chapters address ""molecular biology in a historical framework.... Mapping and various kinds ofmaps (genetic, physical, sequence) are discussed.... (Ge"
Описание: This book presents the statistical aspects of designing, analyzing and interpreting the results of genome-wide association scans (GWAS studies) for genetic causes of disease using unrelated subjects. Particular detail is given to the practical aspects of employing the bioinformatics and data handling methods necessary to prepare data for statistical analysis. The goal in writing this book is to give statisticians, epidemiologists, and students in these fields the tools to design a powerful genome-wide study based on current technology. The other part of this is showing readers how to conduct analysis of the created study. Design and Analysis of Genome-Wide Association Studies provides a compendium of well-established statistical methods based upon single SNP associations. It also provides an introduction to more advanced statistical methods and issues. Knowing that technology, for instance large scale SNP arrays, is quickly changing, this text has significant lessons for future use with sequencing data. Emphasis on statistical concepts that apply to the problem of finding disease associations irrespective of the technology ensures its future applications. The author includes current bioinformatics tools while outlining the tools that will be required for use with extensive databases from future large scale sequencing projects. The author includes current bioinformatics tools while outlining additional issues and needs arising from the extensive databases from future large scale sequencing projects.
Автор: Thomas Kroneis Название: Whole Genome Amplification ISBN: 1493929895 ISBN-13(EAN): 9781493929894 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume mirrors the holistic feature of whole genome amplification (WGA) technology by combining reviews, detailed basic methods and advanced sample workflows.
Описание: An accessible introduction to behavioral epigenetics, The Developing Genome explores how experiences influence genetic activity. We develop as we do not because of the genes we have, but because of what our genes do.
Автор: Happle Rudolf Название: Mosaicism in Human Skin ISBN: 3642387640 ISBN-13(EAN): 9783642387647 Издательство: Springer Рейтинг: Цена: 23058.00 р. Наличие на складе: Поставка под заказ.
Описание: This book presents an overview on the strikingly manifold patterns and peculiarities of mosaic skin disorders. It will help dermatologists understand the underlying molecular mechanisms of skin disorders in order to further improve the treatment outcome.
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