Chemical Sciences in Early Drug Discovery, Seneci, Pierfausto
Автор: Mccabe Название: Unit operations of chemical engineering ISBN: 0071247106 ISBN-13(EAN): 9780071247108 Издательство: McGraw-Hill Рейтинг: Цена: 10123.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Includes separate chapters that are devoted to each of the principle unit operations, grouped into 4 sections: fluid mechanics, heat transfer, mass transfer and equilibrium stages, and operations involving particulate solids. This book contains its balanced treatment of theory and engineering practice, with many practical, illustrative examples.
Описание: This book reviews diversity-oriented synthesis (DOS), a leading and dynamic area in organic chemistry and drug discovery. It first covers key chemical methods for the generation of small molecules according to DOS principles as well as important classes of molecules generated through DOS approaches.
Описание: This book comprehensively describes the development and practice of DNA-encoded library synthesis technology.
Автор: W. Fleischhacker; T. Sch?nfeld Название: Pioneering Ideas for the Physical and Chemical Sciences ISBN: 1489902708 ISBN-13(EAN): 9781489902702 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Josef Loschmidt Symposium held in Vienna, Austria, June 25-27 1995
Автор: Vardanyan, Ruben (university Of Arizona, Tucson, A Название: Piperidine-based drug discovery ISBN: 0128051574 ISBN-13(EAN): 9780128051573 Издательство: Elsevier Science Рейтинг: Цена: 16666.00 р. Наличие на складе: Поставка под заказ.
Описание:
Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives.
Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers.
The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics.
Explores this extremely important heterocycle to a high level of detail
Describes synthesis methods for 70 current drugs based on Piperidine scaffolds
Gives drug designers all the key knowledge required to develop new drugs utilizing Piperidine
Provides pharmacologists a solid overview of the chemical background of existing Piperidine-based drugs
Автор: W. Fleischhacker; T. Sch?nfeld Название: Pioneering Ideas for the Physical and Chemical Sciences ISBN: 0306456842 ISBN-13(EAN): 9780306456848 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Josef Loschmidt Symposium held in Vienna, Austria, June 25-27 1995
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