Genetic Epidemiology, Evangelou

Автор: Austin Melissa
Название: Genetic Epidemiology
ISBN: 1780641818 ISBN-13(EAN): 9781780641812
Издательство: Marston Book Services
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Цена: 8861.00 р.
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Описание: Following an overview of the field, this textbook reviews key genetic concepts, provides an update on relevant genomic technology, and describes methods for assessing the magnitude of genetic influences on diseases and risk factors. It is an essential resource for graduate students in epidemiology and public health genetics.

Автор: Evangelos Evangelou
Название: Genetic Epidemiology
ISBN: 1493993097 ISBN-13(EAN): 9781493993093
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This volume details fast-moving research while providing in-depth descriptions of methods and analytical approaches that are helping to understand the genome and how it is related to complex diseases. Chapters guide the reader through common and rare variation, gene-gene and gene-environment interactions and state-of-the-art approaches for the synthesis of genome-wide and gene expression data. Novel approaches for associations in the HLA region, family-based designs, Mendelian Randomization and Copy Number Variation are also presented. The volume concludes with the challenges researchers face while moving from identifying variants to their functional role and potential drug targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, a thorough presentation of methods and approaches and tips on troubleshooting and avoiding known pitfalls.

Автор: M. Dawn Teare
Название: Genetic Epidemiology
ISBN: 1493957090 ISBN-13(EAN): 9781493957095
Издательство: Springer
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Цена: 16769.00 р.
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Описание:

Part I: Introduction

1. Molecular Genetics and Genetic Variation

Mohammed Elfatih Twfieg and M. Dawn Teare

2. Terminology, Concepts, and Models in Genetic Epidemiology

M. Dawn Teare and Mauro F Santibасez Koref

3. An Introduction to Epidemiology

Cother Hajat

Part II: Genetic Linkage Mapping

4. Genetic Distance and Markers Used in Linkage Mapping

Kristina Allen-Brady and Nicola J. Camp

5. Approaches to Genetic Linkage Analysis

M. Dawn Teare

Part III: Genetic Mapping by Association

6. Fine-Scale Structure of the Genome and Markers Used in Association Mapping

Karen Curtin and Nicola J. Camp

7. Genome-Wide Association Studies

Mark M. Iles

8. Candidate Gene Association Studies

M. Dawn Teare

9. Family-Based Association Studies

Frank Dudbridge

10. Genome Variation: A Review of Web Resources

Andrew Collins and William Tapper

Part IV: Emerging Themes

11. Advanced Methods in Twin Studies

Jaakko Kaprio and Karri Silventoinen

12. Mendelian Randomization: A Tool for Assessing Causality in Observational Epidemiology

Nuala A. Sheehan, Sha Meng, and Vanessa Didelez

13. Copy Number Variation

Louise V. Wain and Martin D. Tobin

14. Epigenetic Variation

Kevin Walters

Part V: Case Studies

15. Modeling the Effect of Susceptibility Factors (HLA and PTPN22) in Rheumatoid Arthritis

Hervй Perdry and Franзoise Clerget-Darpoux

16. Coronary Artery Disease: An Example Case Study

Jennifer H. Barrett

17. The Genetic Epidemiology of Obesity: A Case Study

Laura Johnson

Автор: Suzanne Lentzsch
Название: Genetic and Molecular Epidemiology of Multiple Myeloma
ISBN: 1489998659 ISBN-13(EAN): 9781489998651
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This exploration of the role of protein translation in multiple myeloma covers recent advances in oncogenomic research that further our understanding of the disease`s molecular pathogenesis, and discusses the emerging technique of epigenetic gene silencing.

Автор: Henry T. Lynch; Petre Tautu
Название: Recent Progress in the Genetic Epidemiology of Cancer
ISBN: 3540530223 ISBN-13(EAN): 9783540530220
Издательство: Springer
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Цена: 15372.00 р.
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Описание: The genetic epidemiology of various rare and common tumours is investigated in a study which offers advice on statistical and methodological approaches to experimental design. Information on computer models for data storage and analysis is also provided.

Автор: Bertram K. C. Chan
Название: Biostatistics for Human Genetic Epidemiology
ISBN: 3030067246 ISBN-13(EAN): 9783030067243
Издательство: Springer
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Цена: 27950.00 р.
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Описание: The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solveproblems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems. It begins by introducing all the necessary probabilistic and statistical foundations, before moving on to topics related human genetic epidemiology, with R codes illustrations for various examples. This clear and concise book covers human genetic epidemiology, using R in data analysis, including multivariatedata analysis. It examines probabilistic and statistical theories for modeling human genetic epidemiology – leading the readers through an effective epidemiologic model, from simple to advanced levels. Classical mathematical, probabilistic, and statistical theory are thoroughly discussed and presented. This book also presents R as a calculator and using R in data analysis.Additionally, it covers Advanced Human Genetic Data Concepts, the Study of Human Genetic Variation, Manhattan Plots, as well as the Procedures for Multiple Comparison. Numerous Worked Examples are provided for illustrations of concepts and real-life applications. Biostatistics for Human Genetic Epidemiology is an ideal reference for professionals and students in Medicine (particularly in Preventive Medicine and Public Health Medical Practices), as well as in Genetics, Epidemiology, and Biostatistics.

Автор: Chan
Название: Biostatistics for Human Genetic Epidemiology
ISBN: 3319937901 ISBN-13(EAN): 9783319937908
Издательство: Springer
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Цена: 27950.00 р.
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Описание:

The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solve

Название: Genetic Disorders: Clinical Aspects
ISBN: 1632414988 ISBN-13(EAN): 9781632414984
Издательство: Неизвестно
Цена: 24944.00 р.
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Автор: Manuel Posada de la Paz; Domenica Taruscio; Stephe
Название: Rare Diseases Epidemiology: Update and Overview
ISBN: 3319671421 ISBN-13(EAN): 9783319671420
Издательство: Springer
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Цена: 30745.00 р.
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Описание: The fields of rare diseases research and orphan products development continue to expand with more products in research and development status. In recent years, the role of the patient advocacy groups has evolved into a research partner with the academic research community and the bio-pharmaceutical industry. Unique approaches to research and development require epidemiological data not previously available to assist in protocol study design and patient recruitment for clinical trials required by regulatory agencies prior to approval for access by patents and practicing physicians.

Автор: Christopher Li
Название: Breast Cancer Epidemiology
ISBN: 1489984186 ISBN-13(EAN): 9781489984180
Издательство: Springer
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Цена: 22201.00 р.
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Описание: Breast cancer remains a disease of considerable public health importance worldwide, with over 800,000 new cases diagnosed globally each year. This book is a single comprehensive source of the most recent information on breast cancer epidemiology.