Resistance of Targeted Therapies Excluding Antibodies for Lymphomas, Ferreri

Автор: Joi B. Carter; Amrita Goyal; Lyn McDivitt Duncan
Название: Atlas of Cutaneous Lymphomas
ISBN: 3319354779 ISBN-13(EAN): 9783319354774
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This atlas contains excellent clinical and histopathologic images and text of each of the types of cutaneous lymphoma (around 25 entities).

Автор: Wick
Название: Monoclonal Antibodies in Diagnostic Immunohistochemistry
ISBN: 0824778383 ISBN-13(EAN): 9780824778385
Издательство: Taylor&Francis
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Цена: 53592.00 р.
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Описание: This book describes the methodology of monoclonal antibody-mediated immunohistochemistry, as applied to practical tissue diagnosis. It focuses on human disease and discusses the spectrum of monoclonal antibodies in relation to its utility in solving differential diagnostic problems.

Автор: Chernajovsky
Название: Therapeutic Antibodies
ISBN: 3540732586 ISBN-13(EAN): 9783540732587
Издательство: Springer
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Цена: 49631.00 р.
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Описание: With contributions by numerous experts

Автор: R?diger Schade; Ingrid Behn; Michael Erhard; Andre
Название: Chicken Egg Yolk Antibodies, Production and Application
ISBN: 3662044900 ISBN-13(EAN): 9783662044902
Издательство: Springer
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Цена: 13060.00 р.
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Описание: Polyclonal antibodies, widely used in research and diagnostics, are conventionally isolated from the blood of immunised mammals. The fact that antibodies can also be detected in the yolk of eggs laid by immunised hens, led to the development of the yolk antibody technology as an alternative method less stressful to animals.

Автор: Albitar Maher
Название: Monoclonal antibodies / methods and protocols
ISBN: 1588295672 ISBN-13(EAN): 9781588295675
Издательство: Springer
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Цена: 21661.00 р.
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Описание: Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies.Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy.

Автор: A. Szentivanyi; Paul H. Maurer; Bernard W. Janicki
Название: Antibodies
ISBN: 1461290449 ISBN-13(EAN): 9781461290445
Издательство: Springer
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Цена: 12157.00 р.
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Описание: This publication is based on a Symposium that has been held in Clearwater, Florida on February 19-21, 1986, on antibodies, their structure, synthesis, function, and clinical applicability in disease.

Автор: Juan J. Lafaille; Maria A. Curotto de Lafaille
Название: IgE Antibodies: Generation and Function
ISBN: 3319137247 ISBN-13(EAN): 9783319137247
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.

Автор: Benjamin Bonavida
Название: Resistance to Immunotherapeutic Antibodies in Cancer
ISBN: 1489987320 ISBN-13(EAN): 9781489987327
Издательство: Springer
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Цена: 19589.00 р.
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Описание: This book examines antibody-mediated anti-cancer therapy, covering the use of mAbs against various cancers, developments in the molecular, biochemical and genetic mechanisms of resistance by various mAbs and novel mAbs to overcome drug and radition resistance.

Автор: Benjamin Bonavida
Название: Resistance to Immunotherapeutic Antibodies in Cancer
ISBN: 1461476534 ISBN-13(EAN): 9781461476535
Издательство: Springer
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Цена: 23508.00 р.
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Описание: This book examines antibody-mediated anti-cancer therapy, covering the use of mAbs against various cancers, developments in the molecular, biochemical and genetic mechanisms of resistance by various mAbs and novel mAbs to overcome drug and radition resistance.

Автор: David M. Goldenberg
Название: Cancer Imaging with Radiolabeled Antibodies
ISBN: 1461288053 ISBN-13(EAN): 9781461288053
Издательство: Springer
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Цена: 51570.00 р.
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Описание: It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription.

Автор: Roland E. Kontermann
Название: Bispecific Antibodies
ISBN: 3642432077 ISBN-13(EAN): 9783642432071
Издательство: Springer
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Цена: 30745.00 р.
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Описание: The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation of new classes of bispecific antibodies lacking these obstacles. In addition, new applications were established, such as pre-targeting strategies in radioimmunotherapy and dual targeting approaches in order to improve binding, selectivity and efficacy. In this book, the different ways of generating bispecific antibodies are described, with emphasis on recombinant formats. The various applications of bispecific antibodies, e.g. in cellular cancer immunotherapy, radioimmunotherapy and pretargeting strategies are covered, and emerging applications such as dual targeting strategies, which involve the simultaneous inhibition of two targets, are addressed.

Автор: Antonino Cattaneo; Silvia Biocca
Название: Intracellular Antibodies
ISBN: 3662079941 ISBN-13(EAN): 9783662079942
Издательство: Springer
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Цена: 6986.00 р.
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Описание: Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells.