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Sesquiterpene Lactones, S?lsen


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Цена: 13974.00р.
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Автор: S?lsen
Название:  Sesquiterpene Lactones
ISBN: 9783319782737
Издательство: Springer
Классификация:


ISBN-10: 3319782738
Обложка/Формат: Hardcover
Страницы: 371
Вес: 0.75 кг.
Дата издания: 2018
Язык: English
Издание: 1st ed. 2018
Иллюстрации: 11 tables, color; 14 illustrations, color; 158 illustrations, black and white; xxii, 371 p. 172 illus., 14 illus. in color.
Размер: 234 x 156 x 22
Читательская аудитория: Professional & vocational
Основная тема: Medicinal Chemistry
Подзаголовок: Advances in their Chemistry and Biological Aspects
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание:

PART I- CHEMICAL AND BIOCHEMICAL ASPECTS


1. Sesquiterpene lactones. Overview (V. Sьlsen, V. Martino - Argentina)

2. Taxonomy (G. Giberti)

3. Biosynthesis and biotechnology (M. Perassolo, J. Rodriguez Talou- Argentina)

4. Chemistry (Francis Barrios - USA)

4.1. Synthesis of sesquiterpene lactones

4.2. Chemical transformation of sesquiterpene lactones

5. Analytical procedures (V. Sьlsen, V. Martino, C. Catalбn - Argentina; S.M. Adekenov- Kazakhstan)

5.1. Extraction and isolation

5.2. Identification. Spectroscopic methods


PART II- BIOLOGICAL ACTIVITIES


6. Trypanocidal and leishmanicidal activities (S. Cazorla, A. Bivona, N. Cerny - Argentina)

7. Mode of action of sesquiterpene lactones on Trypanosoma and Leishmania spp. , (E. Lombardo, M. Sosa, E. Lozano, P. Barrera, R. Spina - Argentina)

7.1. Molecular targets

7.2. Contribution of microscopy for understanding the mechanism of action of sesquiterpene lactones

8. Effect of sesquiterpene lactones on other microorganisms (antibacterial, antifungal, antiviral and antiplasmodial) (authorship to confirm)

9. Antiproliferative and cytotoxic activities (C. Anesini, R. Martino - Argentina)

10. Anti-inflammatory activity (M.R. Alonso)


PART III- SESQUITERPENE LACTONES: MEDICINAL CHEMISTRY APPROACH


11. Structure-activity relationship (T. Schmidt - Germany)

11.1. Structure -antiprotozoal activity relationship

11.2. Structure -antiproliferative activity relationship

11.3. Structure -anti-inflammatory activity relationship (authorship to confirm)




Sesquiterpene Lactones

Автор: Valeria Patricia S?lsen; Virginia Susana Martino
Название: Sesquiterpene Lactones
ISBN: 3030086607 ISBN-13(EAN): 9783030086602
Издательство: Springer
Рейтинг:
Цена: 18167.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book addresses chemical and biological aspects related to sesquiterpene lactones (STLs). Experts in different fields have been invited to contribute on this class of compound's chemistry, isolation and identification, biological activities (antibacterial, antifungal, antiviral, antitrypanosomal, antileishmanial,antiplasmodial, antiproliferative and antiinflammatory), synthesis, biosynthesis, derivatization and QSAR analysis. Taxonomic and chemotaxonomic aspects related to the Asteraceae family are also contributed. The book begins by describing the chemical characteristics of STLs, their classification in different skeleton types, synthesis, distribution in nature and their most important biological properties. An overview of the group's main representatives, based on their importance for human health, as well as an update of the most recently isolated STLs, follow. The authors also provide an overview of the most common methods described in the literature for the extraction, purification, identification and structure elucidation of STLs, while also highlighting more recently developed methods. Furthermore, experts in the field provide an in-depth discussion of the most commonly employed in vitro and in vivo antiprotozoal assays against the different stages of parasites, as well as STLs' properties as anticancer agents in numerous cancer cell lines and animal models. Lastly, the book presents examples of the in vitro and in vivo activity of STLs and their mechanism of antiprotozoal action, together with an analysis of ultrastructural alterations, observed using TEM techniques. The book is aimed at scientists working on natural products: both those investigating this particular group of compounds and those who wish to further explore its potential as new drugs for medical conditions such as protozoal diseases and cancer.

Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of ?-Aryl Ketones

Автор: Robert Doran
Название: Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of ?-Aryl Ketones
ISBN: 3319205439 ISBN-13(EAN): 9783319205434
Издательство: Springer
Рейтинг:
Цена: 16979.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis.

Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of ?-Aryl Ketones

Автор: Robert Doran
Название: Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of ?-Aryl Ketones
ISBN: 3319370340 ISBN-13(EAN): 9783319370347
Издательство: Springer
Рейтинг:
Цена: 14365.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis.


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