Delta Opioid Receptor Pharmacology and Therapeutic Applications, Jutkiewicz
Автор: Ying Xia Название: Neural Functions of the Delta-Opioid Receptor ISBN: 3319254936 ISBN-13(EAN): 9783319254937 Издательство: Springer Рейтинг: Цена: 28734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is the first to summarize the progress of research on neural functions of the the delta opioid receptor (DOR) to date. The book will provide a comprehensive overview of the current state of DOR research and provide a blueprint for future directions.ГЇВїВЅ
Автор: Santi M. Spampinato Название: Opioid Receptors ISBN: 1493917072 ISBN-13(EAN): 9781493917075 Издательство: Springer Рейтинг: Цена: 23757.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Opioid Receptors: Methods and Protocols serves as a comprehensive guide to both key new techniques and established methods for the investigation of genetics, structural biology, transcription, and post-transcriptional events of opioid receptors.
Автор: Santi M. Spampinato Название: Opioid Receptors ISBN: 1493955500 ISBN-13(EAN): 9781493955503 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Opioid Receptors: Methods and Protocols serves as a comprehensive guide to both key new techniques and established methods for the investigation of genetics, structural biology, transcription, and post-transcriptional events of opioid receptors. Other methods cover the cellular detection and trafficking of opioid receptors in vitro and in vivo. Procedures aimed to investigate signaling pathways modulated by opioid receptors and model systems to study opioid receptor-mediated functions are also included. Finally, methods to assay behavioral effects mediated by opioid receptors are described. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective introductions, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Wide-ranging and authoritative, Opioid Receptors: Methods and Protocols will help both experienced and new entrants in this field to carry out their experiments successfully and with new inspiration.
Автор: Foreman J. Название: Textbook of Receptor Pharmacology ISBN: 0849310296 ISBN-13(EAN): 9780849310294 Издательство: Taylor&Francis Рейтинг: Цена: 13168.00 р. Наличие на складе: Поставка под заказ.
Описание: The bestselling first edition of Textbook of Receptor Pharmacology originated from a renowned course in receptor pharmacology taught at the University College of London for the past three decades. Its innovative format united four major approaches to the study of receptors: molecular biology, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction systems. The second edition builds on this foundation.This edition streamlines the material and focuses on cell membrane receptors along with their immediate signal transducers. The section on the molecular structure of receptors reflects the advances in this area. This edition also includes two restructured new chapters, one on G-proteins and one on tyrosine kinases, as signal transductors. Several chapters also contain problems for students to solve as well as worked-out solutions.The book contains over one hundred useful diagrams and tables to aid illustration of concepts and a helpful appendix explaining the simple mathematics used in the text. A time-saving resource and comprehensive textbook, Textbook of Receptor Pharmacology, Second Edition provides in-depth, up-to-date coverage of this
Описание: "Drug-Receptor Thermodynamics" covers the general principles of thermodynamics and its use and utility in pharmacology; provides a review of actual applications arranged according to receptor categories; and discusses the potential for thermodynamics to some day predict drug action.
Автор: Ehlert Frederick J Название: Affinity And Efficacy: The Components Of Drug-Receptor Interactions ISBN: 9814322563 ISBN-13(EAN): 9789814322560 Издательство: World Scientific Publishing Рейтинг: Цена: 38016.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The interaction of a drug with a receptor encodes a vector of information having components of affinity and efficacy. This book describes how to analyze various responses to estimate the affinity and efficacy components of the initial drug-receptor interaction.
Автор: Gurevich Название: G Protein-Coupled Receptor Kinases ISBN: 1493937960 ISBN-13(EAN): 9781493937967 Издательство: Springer Рейтинг: Цена: 19564.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This collection explores up-to-date descriptions of known G protein-coupled receptor kinase (GRK)-dependent mechanisms, both associated with G protein-coupled receptor (GPCR) functions and the receptor-independent. The chapters cover a wide range of studies from invertebrates to humans, with sections of the volume covering GRK structure, mechanisms of activation, and interaction with GPCRs, GRKs in cell signaling, as well as physiological and pathophysiological mechanisms regulated by GRKs. Written for the Methods in Pharmacology and Toxicology series, this book features the kind of practical detail necessary for success in the laboratory.
Authoritative and timely, G Protein-Coupled Receptor Kinases features the kind of comprehensive mechanistic elucidation of GRK functions and their regulation in cells necessary for a better understanding of cell biology as well as for devising novel research approaches and therapeutic strategies.
Автор: Li Название: Nicotinic Acetylcholine Receptor Technologies ISBN: 1493937669 ISBN-13(EAN): 9781493937660 Издательство: Springer Рейтинг: Цена: 18167.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides properties, biological function, methods,and approaches for manipulating nAChRs in different organisms. NicotinicAcetylcholine Receptor Technologies guides readers through moleculartechniques and behavioral tests used to investigate nicotinic drugs,chronoamperometry, emerging technologies and methods for the analysis ofnAChRs, single nucleotide polymorphism (SNP), fluorescence techniques, spectralconfocal, allosteric modulators of a7-nAChRs, and a comprehensive evolutionalrelation for most nAChR subunits, in both vertebrate and invertebrate species.Written for the popular Neuromethods series, chapters include thekind of detail and key implementation advice that ensures successful results inthe laboratory. Authoritative and practical, Nicotinic AcetylcholineReceptor Technologies aims to ensure successful results in thefurther study of this vital field.
Автор: Vincent Laudet Название: The Nuclear Receptor FactsBook, ISBN: 0124377351 ISBN-13(EAN): 9780124377356 Издательство: Elsevier Science Рейтинг: Цена: 12464.00 р. Наличие на складе: Поставка под заказ.
Описание: Devoted to nuclear receptors, this work presents an introduction and describes the mode of action of the receptors in general. It also contains detailed entries covering each type of receptor. Entries provide information on: Nomenclature and structure; Isolation; DNA binding properties; Ligands; Expression; Target genes; Knockouts; and more.
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