Modelling Proteasome Dynamics in a Bayesian Framework, St?bler

Автор: Peter Zwickl; Wolfgang Baumeister
Название: The Proteasome — Ubiquitin Protein Degradation Pathway
ISBN: 3642639712 ISBN-13(EAN): 9783642639715
Издательство: Springer
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Описание: The penultimate chapter rounds up the in- formation on intracellular distribution of proteasomes in yeast and mammalian cells, while the last contribution highlights proteasome inhibitors, tools which proved to be very valuable for dissecting the cellular roles of the proteasome and which might turn out to be of pharmacological importance.

Автор: Leonidas Stefanis; J. N. Keller
Название: The Proteasome in Neurodegeneration
ISBN: 1489973451 ISBN-13(EAN): 9781489973450
Издательство: Springer
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Описание: One major factor that has been relatively obscure until recently has been the contribution of protein degradation to the regulation of the steady state level of protein expression and protein function.