Advances in Chromatographic Techniques for Therapeutic Drug Monitoring 9781138111714

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Название: Advances in Chromatographic Techniques for Therapeutic Drug Monitoring
ISBN: 9781138111714
Издательство: Taylor&Francis
Классификация:

Фармакология

ISBN-10: 1138111716
Обложка/Формат: Paperback
Страницы: 475
Вес: 0.89 кг.
Дата издания: 16.06.2017
Язык: English
Иллюстрации: 58 tables, black and white; 92 illustrations, black and white
Размер: 254 x 178 x 24
Читательская аудитория: General (us: trade)
Ключевые слова: Pharmaceutical technology, MEDICAL / Pharmacology
Основная тема: Clinical Implementation
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

For drugs with a narrow therapeutic index, therapeutic drug monitoring methods are essential for patient management. Although immunoassays are commercially available for many drugs and most laboratories use these assays for routine therapeutic monitoring, they have many limitations which hinder their efficacy. Providing practical guidelines for implementing preferred gas and liquid chromatographic methods, Advances in Chromatographic Techniques for Therapeutic Drug Monitoring is a comprehensive reference describing the theory and application of therapeutic drug monitoring in clinical laboratories.

Edited by a distinguished authority in the field and containing contributions from a variety of experts, the book discusses preanalytical variables, the pitfalls of immunoassays, tandem mass spectrometry, issues related to pain management and herbal supplements, and therapeutic drug monitoring for a range of medications, including:

Anticonvulsants
Digitalis
Cardioactive drugs
Antidepressants
Immunosuppressants
Anti-cancer drugs
Vancomycin and aminoglycosides
Antibiotics
Antiretroviral drugs
Nonnarcotic analgesics
Anti-inflammatory drugs

Examing older and newer drugs, the book contains detailed discussions on the rationale for therapeutic drug monitoring of each class of drugs, along with their basic pharmacology and toxicology. An extensive list of references is provided at the end of each chapter so that those interested in implementing a new drug assay can find the most appropriate method for the intended drug.

Advances in Chromatographic Techniques for Therapeutic Drug Monitoring,