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Cancer Systems Biology, 


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Цена: 11176.00р.
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При оформлении заказа до: 2025-07-28
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Название:  Cancer Systems Biology
ISBN: 9781138113299
Издательство: Taylor&Francis
Классификация:



ISBN-10: 1138113298
Обложка/Формат: Paperback
Страницы: 456
Вес: 0.87 кг.
Дата издания: 14.06.2017
Серия: Chapman & hall/crc computational biology series
Язык: English
Иллюстрации: 26 tables, black and white; 32 illustrations, color; 72 illustrations, black and white
Размер: 254 x 178
Читательская аудитория: Tertiary education (us: college)
Ключевые слова: Biophysics, SCIENCE / Biotechnology,SCIENCE / Life Sciences / Biology,SCIENCE / Physics / General
Основная тема: Biophysics
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis, cancer researchers can uncover a series of new discoveries and biological insights.

The First Cancer Systems Biology Book Designed for Computational and Experimental Biologists
Unusual in its dualistic approach, Cancer Systems Biology discusses the recent progress in the understanding of cancer systems biology at a time when more and more researchers and pharmaceutical companies are looking into a systems biology approach to find drugs that can effectively be used to treat cancer patients.

Includes Contributions from more than 30 International Experts
Part I introduces basic concepts and theories of systems biology and their applications in cancer research, including case studies of current efforts in cancer systems biology. Part II discusses basic cancer biology and cutting-edge topics of cancer research for computational biologists. In contains an overview of genomics, cell signaling, and tumorigenesis, in addition to hot topics like molecular mechanisms of cancer metastasis and the molecular relationships between solid tumors, their microenvironments, and tumor blood vessels. Rounding out the books solid coverage, Part III explores a variety of computational tools and public data resources that are useful for studying cancer problems at a systems level.

Cancer systems biology is still in its infancy as a field of study, but it is fast becoming indispensable in the battle to defeat cancer and develop successful new treatments. Cancer Systems Biology marks an important step toward reaching that goal.




Epidemiology:  Key to Public Health. 2 ed.

Автор: Krickeberg Klaus, Van Trong Pham, Thi My Hanh Pham
Название: Epidemiology: Key to Public Health. 2 ed.
ISBN: 3030163679 ISBN-13(EAN): 9783030163679
Издательство: Springer
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Цена: 9782.00 р. 13974.00 -30%
Наличие на складе: Есть (2 шт.)
Описание: ?This unique textbook presents the field of modern epidemiology as a whole; it does not restrict itself to particular aspects. It stresses the fundamental ideas and their role in any situation of epidemiologic practice. Its structure is largely determined by didactic viewpoints.Epidemiology is the art of defining and investigating the influence of factors on the health of populations. Hence the book starts by sketching the role of epidemiology in public health. It then treats the epidemiology of many particular diseases; mathematical modelling of epidemics and immunity; health information systems; statistical methods and sample surveys; clinical epidemiology including clinical trials; nutritional, environmental, social, and genetic epidemiology; and the habitual tools of epidemiologic studies. The book also reexamines the basic difference between the epidemiology of infectious diseases and that of non-infectious ones.The organization of the topics by didactic aspects makes the book ideal for teaching. All examples and case studies are situated in a single country, namely Vietnam; this provides a particularly vivid picture of the role of epidemiology in shaping the health of a population. It can easily be adapted to other developing or transitioning countries.This volume is well suited for courses on epidemiology and public health at the upper undergraduate and graduate levels, while its specific examples make it appropriate for those who teach these fields in developing or emerging countries. New to this edition, in addition to minor revisions of almost all chapters:• Updated data about infectious and non-infectious diseases• An expanded discussion of genetic epidemiology• A new chapter, based on recent research of the authors, on how to build a coherent system of Public Health by using the insights provided by this volume.

Introductory Physics for Biological Scientists

Автор: Aegerter Christof M.
Название: Introductory Physics for Biological Scientists
ISBN: 1108466508 ISBN-13(EAN): 9781108466509
Издательство: Cambridge Academ
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Цена: 9979.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: An introduction to the fundamental physical principles related to the study of biological phenomena. Chapters are structured around biological examples, and the topics covered include waves, optics and mechanics. With quiz questions and a detailed appendix, it is perfect for students looking to develop their quantitative and analytical tools.

The Role of Model Integration in Complex Systems Modelling

Автор: Manish Patel; Sylvia Nagl
Название: The Role of Model Integration in Complex Systems Modelling
ISBN: 3642422950 ISBN-13(EAN): 9783642422959
Издательство: Springer
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Цена: 16977.00 р.
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Описание: With no similar books on the market, this volume is a welcome addition. Many current methods use `shallow integration` that employ output-input linking. This book goes further, setting out a systems biology and tumour modeling method called `deep integration`.

Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract

Автор: Jansen
Название: Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract
ISBN: 3319413864 ISBN-13(EAN): 9783319413860
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This book is a comprehensive understanding of the evolution of pre-malignant disease, emphasizing common themes in the field, including stem cell biology and histologic modes of cancer progression between the distal esophagus and stomach. Its sixteen chapters discuss metaplastic tissue change in the upper GI, clonalexpansion of early neoplasia, stem cell dynamics in experimental models, pathology of early esophageal squamous cell carcinoma, therapeutic modalities for esophageal squamous cell carcinoma, pathology of Barrett’s esophagus, screening, early detection and novel diagnostic tools for Barrett's esophagus, clonal evolution of Barrett’s esophagus, endoscopic therapeutic modalities of early esophageal cancer, pathology of early gastric cancer, and experimental models for gastric cancer. Stem Cells, Pre-neoplasia and Early Cancer of the Upper Gastrointestinal Tract is an integrative text on both the current state of translational research on every cancer development of the upper gastrointestinal tract as well as on novel clinical diagnostic and therapeutic modalities. It highlights a rapidly growing field within cancer research and is essential reading for oncologists, biochemists and advanced graduate students alike. Springer’s Advances in Experimental Medicine and Biology series presents multidisciplinary and dynamic findings in the broad fields of experimental medicine and biology. The wide variety in topics it presents offers readers multiple perspectives on a variety of disciplines including neuroscience, microbiology, immunology, biochemistry, biomedical engineering and cancer research.

The Physics of Cancer

Автор: La Porta
Название: The Physics of Cancer
ISBN: 1107109590 ISBN-13(EAN): 9781107109599
Издательство: Cambridge Academ
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Цена: 9187.00 р.
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Описание: Addressing key aspects of cancer research from an interdisciplinary perspective and presenting analytical, quantitative and computational models, this book is a pedagogical introduction to cancer for physics students and researchers, as well as a reference text for cancer biologists interested in quantitative tools and approaches from physics.

Gliomas

Автор: J. Hekmatpanah
Название: Gliomas
ISBN: 3642809189 ISBN-13(EAN): 9783642809187
Издательство: Springer
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Цена: 18284.00 р.
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Описание: Symposium on "Cerebral Gliomas" held at Chicago, May 18-19, 1974

Biological Basis of Alcohol-Induced Cancer

Автор: Vasilis Vasiliou; Samir Zakhari; Helmut K. Seitz;
Название: Biological Basis of Alcohol-Induced Cancer
ISBN: 3319096133 ISBN-13(EAN): 9783319096131
Издательство: Springer
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Цена: 23757.00 р.
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Описание: In the recent years, a significant amount of research has emerged connecting the link between alcohol and cancer. This proceedings volume will contain chapters based upon the presentation of the 2nd International Conference on Alcohol and Cancer in Colorado, 2013.

Stem Cell Biology in Neoplasms of the Central Nervous System

Автор: Moneeb Ehtesham
Название: Stem Cell Biology in Neoplasms of the Central Nervous System
ISBN: 3319165364 ISBN-13(EAN): 9783319165363
Издательство: Springer
Рейтинг:
Цена: 19564.00 р.
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Описание: This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.

Cancer Systems Biology, Bioinformatics and Medicine

Автор: Alfredo Cesario; Frederick Marcus
Название: Cancer Systems Biology, Bioinformatics and Medicine
ISBN: 9401783659 ISBN-13(EAN): 9789401783651
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.

Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology

Автор: Denis Corbeil
Название: Prominin-1 (CD133): New Insights on Stem & Cancer Stem Cell Biology
ISBN: 1489986928 ISBN-13(EAN): 9781489986924
Издательство: Springer
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Цена: 22201.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book provides exciting new research on prominin-1/CD133. It evaluates this glycoprotein as a stem cell marker for cancers and other diseases and presents future prospects for its potential role in regenerative therapy.

Prostate Cancer

Автор: Donald J. Tindall
Название: Prostate Cancer
ISBN: 1489986626 ISBN-13(EAN): 9781489986627
Издательство: Springer
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Цена: 26120.00 р.
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Описание: This book reviews biochemistry, molecular biology and genetic changes in prostate cells that are the driving forces in the initiation and progression of cancer. Surveys cell interactions, including stem cells, reactive Stromal cells and membrane lipid rafts.

Central Nervous System Metastasis, the Biological Basis and Clinical Considerations

Автор: Diane Palmieri
Название: Central Nervous System Metastasis, the Biological Basis and Clinical Considerations
ISBN: 9401782016 ISBN-13(EAN): 9789401782012
Издательство: Springer
Рейтинг:
Цена: 23757.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume will cover what is known regarding the biology and treatment of CNS metastasis, including novel chapters such as the future of targeted therapies. It will begin with an overview of the natural history and risk factors for CNS metastases that will broadly cover all cancer histologies. This will be followed by 3 chapters that will cover the biology. These include: molecular biology, discussing what is known about specific genes/proteins involved in the process and model systems to study brain metastasis; the brain microenvironment, focusing on how it is different from the microenvironment of other organs of the body; and the blood-brain barrier, which includes a discussion of permeability with respect to brain metastases. A chapter on experimental imaging will cover both the biology of brain metastasis from an imaging perspective and use of imaging techniques to study brain metastases. The clinical chapters will discuss treatment options with separate chapters on surgery, chemotherapy and radiation. In addition, leptomeningeal metastasis will be given its own chapter. Finally, quality of life issues will be the concluding chapter.


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