Rowland and Tozer`s Clinical Pharmacokinetics and Pharmacodynamics:, Derendorf
Старое издание
Автор: Rowland Название: Clinical Pharmacokinetics and Pharmacodynamics, 4e ISBN: 0781750091 ISBN-13(EAN): 9780781750097 Издательство: Lippincott Williams & Wilkins Цена: 12012.00 р. Наличие на складе: Невозможна поставка. Описание: Reflects the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This title also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs.
Автор: Gopal B. Saha Название: Fundamentals of Nuclear Pharmacy ISBN: 3319575791 ISBN-13(EAN): 9783319575797 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases.
Автор: Bauer Название: Applied Clinical Pharmacokinetics ISBN: 0071794581 ISBN-13(EAN): 9780071794589 Издательство: McGraw-Hill Рейтинг: Цена: 12697.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Helps you learn the clinical application of pharmacokinetics. This book delivers clear and clinically relevant coverage of drug dosing and drug monitoring that no other text can match. It offers the standardized techniques and approaches to patient-specific dosing, and information on pharmacokinetically monitored drugs.
Автор: Michelle A. Rudek; Cindy H. Chau; William D. Figg; Название: Handbook of Anticancer Pharmacokinetics and Pharmacodynamics ISBN: 1493938983 ISBN-13(EAN): 9781493938988 Издательство: Springer Рейтинг: Цена: 34937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. * Road map to anticancer drug development from discovery to NDA submission * Discussion of molecular targets and preclinical screening * Development and validation of bioanalytical methods * Chapters on clinical trial design and phase 0, I, II, III clinical trials * Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents * Review of the drug development process from both laboratory and clinical perspectives * New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development
Описание: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.
Автор: Rescigno Aldo Название: Foundations of Pharmacokinetics ISBN: 0306477041 ISBN-13(EAN): 9780306477041 Издательство: Springer Рейтинг: Цена: 26122.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is divided into two parts; in the first part the principles and the methods of pharmacokinetics are described in detail, while in the second the main pharmacokinetic parameters are described, giving for each of them the definition, the principal properties, and the methods of determination. An appendix contains the important mathematical instruments used in the main part of the book, namely the operational calculus and the convolution integral. In the second part there is a careful distinction among pharmacokinetic parameters, i.e., parameters that represent a true pharmacokinetic property, model parameters, i.e., parameters that represent a property of a specific model, and incidental parameters, i.e., parameters that represent only the result of a particular experiment. Special care is taken to distinguish between the definition of a parameter, and the properties that derive from that definition; a considerable emphasis is also given to the fact that each method for the determination of a parameter is dependent on the specific model it is based on.
Автор: Peter L. Bonate; Danny R. Howard Название: Pharmacokinetics in Drug Development ISBN: 1489977996 ISBN-13(EAN): 9781489977991 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The topics chosen for this volume were selected because they are some of the current development or technological issues facing drug development project teams. They regard the practical considerations for assessment of selected special development populations. For example, they include characterization of drug disposition in pregnant subjects, for measuring arrhythmic potential, for analysis tumor growth modeling, and for disease progression modeling. Practical considerations for metabolite safety testing, transporter assessments, Phase 0 testing, and development and execution of drug interaction programs reflect current regulatory topics meant to address enhancement of both safety assessment and early decision-making during new candidate selection. Important technologies like whole body autoradiography, digital imaging and dried blood spot sample collection methods are introduced, as both have begun to take a more visible role in pharmacokinetic departments throughout the industry.
Автор: Aldo Rescigno Название: Foundations of Pharmacokinetics ISBN: 1475787391 ISBN-13(EAN): 9781475787399 Издательство: Springer Рейтинг: Цена: 22359.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book has its origin in my experience as a teacher of pharmacokinetics in many universities in four different continents. Chapters 13 to 17 show how different parameters of importance in pharmacokinetics can be exactly defined and measured.
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