Nanotechnology and microfluidics, Jiang X

Dr Rapp fully engages with the multidisciplinary nature of the subject. Alongside traditional fluid/transport topics, there is a wealth of coverage of materials and manufacturing techniques, chemical modification/surface functionalization, biochemical analysis, and the biosensors involved.

As well as providing a clear and concise overview to get started into the multidisciplinary field of microfluidics and practical guidance on techniques, pitfalls and troubleshooting, this book supplies:

• A set of hands-on experiments and protocols that will help setting up lab experiments but which will also allow a quick start into practical work.
• A collection of microfluidic structures, with 3D-CAD and image data that can be used directly (files provided on a companion website).

• A practical guide to the successful design and implementation of nano- and microfluidic processes (e.g. biosensing) and equipment (e.g., biosensors, such as diabetes blood glucose sensors).
• Provides techniques, experiments, and protocols ready to be put to use in the lab, in an academic, or industry setting.
• A collection of 3D-CAD and image files is provided on a companion website.

The unique properties of microfluidic technologies, such as rapid sample processing and precise control of fluids in assay have made them attractive candidates to replace traditional experimental approaches.

Practical for students, instructors, and researchers, this book provides a much-needed, comprehensive new laboratory reference in this rapidly growing and exciting new field of research.

Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit details proven approaches for the detection of single cells and even single molecules--approaches employed by the world's foremost microfluidics and nanotechnology laboratories. While similar books concentrate only on microfluidics or nanotechnology, this book focuses on the combination of soft materials (elastomers and other polymers) with hard materials (semiconductors, metals, and glass) to form integrated detection systems for biological and chemical targets. It explores physical and chemical--as well as contact and noncontact--detection methods, using case studies to demonstrate system capabilities. Presenting a snapshot of the current state of the art, the text:

• Explains the theory behind different detection techniques, from mechanical resonators for detecting cell density to fiber-optic methods for detecting DNA hybridization, and beyond
• Examines microfluidic advances, including droplet microfluidics, digital microfluidics for manipulating droplets on the microscale, and more
• Highlights an array of technologies to allow for a comparison of the fundamental advantages and challenges of each, as well as an appreciation of the power of leveraging scalability and integration to achieve sensitivity at low cost

Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit not only serves as a quick reference for the latest achievements in biochemical detection at the single-cell and single-molecule levels, but also provides researchers with inspiration for further innovation and expansion of the field.