Описание: This book presents key concepts in the structure and function of vascular smooth muscle cells in health and disease. Supplemental reading may be drawn from the extensive references listed at the end of each chapter. Vascular smooth muscle cell is the major cell type in blood vessels. Dysfunction of vascular smooth muscle cells is an important cause of vascular diseases, for example, atherosclerosis, hypertension, and circulatory shock. Vascular smooth muscle cells are phenotypically plastic, capable of switching between two major phenotypes -- contractile/differentiated phenotype and invasive/proliferative phenotype in response to environmental clues. Chapter 1 introduces the major areas of research presented in this monograph. Chapters 2 to 4 address the structure and function of the contractile/differentiated phenotype of vascular smooth muscle cell. Chapters 5 and 6 address the developmental basis of vascular smooth muscle cell phenotype and structure and function of podosomes (invasive organelles) in the invasive/proliferative phenotype of vascular smooth muscle cell. Chapters 7 to 9 address the role of vascular smooth muscle cell dysfunction in vascular diseases -- atherosclerosis, hypertension, and circulatory shock.
Описание: Instead of presenting a collation of conference reports with much overlap between them, this book has been written specially for the purpose of surveying the literature up to early 1987 in the snRNP field in a coherent manner, each of the seven chapters having been produced by connoisseurs of their field.
Описание: Proceedings of the Second International Conference: "Structure and Function of Molecules Involved in Leucocyte Adhesion II", Held in Titisee, Germany, October 2-6, 1991
Описание: In recent years, the ATP synthase (H+-ATPase, FoFrATPase) has been the subject of intensive IDvestigations in many laboratories. The major reason for this lies in the fact that this enzyme complex catalyses one of the most important reactions in living cells, namely the synthesis of ATP utilizing the energy from an electrochemical transmembrane H+ gradient, generated by the cellular respiratory chain or by the light reactions of photosynthetic organisms. The mechanism by which the H+ motive force is utilized to drive the synthesis of ATP is one of the major unsolved problems in biochemistry. Thus, the fundamental information concerning the-molecular structure and the mechanism of assembly of the ATP synthase is of major significance in cell biology. A seminar/workshop on the Molecular Structure, Function and Assembly of the ATP synthases was held in April, 1987 at the East-West Center, University of Hawaii, Honolulu, Hawaii, to promote exchange of information between laboratories actively engaged in the study of the A TP synthases, and to provide a forum for discussion and coordination of data derived from molecular, genetic and biochemical approaches used in different laboratories. This volume summarizes the result of the seminar/workshop, in the form of a collection of papers presented at the meeting, and provides an overvIew of current work in this rapidly progressing area of research.
Автор: Wolfgang Hennig Название: Structure and Function of Eukaryotic Chromosomes ISBN: 3662224380 ISBN-13(EAN): 9783662224380 Издательство: Springer Рейтинг: Цена: 16769.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents an overview of various aspects of chromosome research, written by leading experts of the respective fields, combining classic and recent molecular biological results. The variety and comprehensiveness make it a handbook of chromosome research for all scientists, teachers and graduate students interested in this field. Dieses Buch fa?t die unterschiedlichen Aspekte der Chromosomenforschung in Beitr?gen von f?hrenden Wissenschaftlern zusammen, wobei die klassischen Erkenntnisse mit neuesten Forschungsdaten zu einem umfassenden ?berblick ?ber das Gebiet kombiniert werden.
Автор: B.B. Biswas; Siddhartha Roy Название: Proteins: Structure, Function, and Engineering ISBN: 0306448467 ISBN-13(EAN): 9780306448461 Издательство: Springer Рейтинг: Цена: 34799.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Here, researchers review the latest breakthroughs in protein research. Articles examine the possibility of a Boltzman-like distribution in protein substructures, the new technique of Raman spectroscopy, and compact intermediate states of protein folding.
Автор: Martin Gibbs Название: Structure and Function of Chloroplasts ISBN: 3642883095 ISBN-13(EAN): 9783642883095 Издательство: Springer Рейтинг: Цена: 15672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It is now about 100 years since the chloroplast has been recognized as the site of photosynthesis in plant cells. The last 20 years have seen a striking increase in interest in the structure and function of the chloroplast. Hastened on by powerful new tools such as the electron microscope and the newer methods of isolation and analysis of chloroplasts, there is presently considerable experimental work on the properties of this organelle. In such a rapidly moving field and one which is reviewed systematically is various Annual Reviews, it is not possible to present a detailed critique of the prolific literature in a book of reasonable size. Rather the decision was made to sacrifice complete coverage of the field and to indicate general areas of investigation. In organization, problems here dealt with, are those concerned with the electron microscopy of chloroplast structure, development and conformation, genetic control of chloroplast development, characterization of some of the major components of the chloroplast and the biochemical properties of the chloroplast including the for- mation of adenosine triphosphate and reduced pyridine nucleotide and the assim- ilation of carbon dioxide into carbohydrate with subsequent conversion to second- ary products. A historical outline on the general subject Photosynthesis and the Chloroplast has been included to place into proper perspective the rapid developments in the several areas covered in the book. I am particularly indebted to Dr. Roy E.
Автор: J.R. Harris; I.B. Zbarsky Название: Nuclear Structure and Function ISBN: 1461279186 ISBN-13(EAN): 9781461279181 Издательство: Springer Рейтинг: Цена: 12157.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The overall sequence is as follows: Genome structure, Gene Structure and Expression, Nucleolar Genes, Structure and Proteins, Chromatin and Nuclear Granules, Nuclear Matrix and Nuclear Proteins, Replication and Transcription and finally Nuclear Envelope and Nuclear Cytoplasmic Transport.
Автор: Lars Svennerholm Название: Structure and Function of Gangliosides ISBN: 146847846X ISBN-13(EAN): 9781468478464 Издательство: Springer Рейтинг: Цена: 6986.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume records the proceedings of an International Symposium on The Structure and Function of Gangliosides, held at Le Bischenberg, Alsace, France, in April 23-27, 1979.
Автор: Engelbert Buxbaum Название: Fundamentals of Protein Structure and Function ISBN: 3319792903 ISBN-13(EAN): 9783319792903 Издательство: Springer Рейтинг: Цена: 13974.00 р. Наличие на складе: Поставка под заказ.
Автор: Zengrong Liu; Jianwei Shen; Shuiming Cai; Fang Yan Название: MicroRNA Regulatory Network: Structure and Function ISBN: 9402415750 ISBN-13(EAN): 9789402415759 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses topics related to the topological structure and biological function of gene networks regulated by microRNAs. It focuses on analyzing the relation between topological structure and biological function, applying these theoretical results to gene networks involving microRNA, illustrating their biological mechanisms, and identifying the roles of microRNA in controlling various phenomena emerging from the networks. In addition, the book explains how to control the complex biological phenomena using mathematical tools and offers a new perspective on studying microRNA. It is a useful resource for graduate students and researchers who are working on or interested in microRNAs and gene network.
Ribosome biogenesis is the process of making ribosomes which are responsible for mRNA translation into proteins. It is a tightly regulated process closely linked to nearly all biochemical and cellular processes, including cell division, growth, and development. Emerging Concepts in Ribosome Structure, Biogenesis, and Function provides a synthesized overview of all the parts engaged in this process. The book begins by providing an introduction to the ribosome factory, its origin, and its evolution of translation. It then goes on to describe ribosome structure including subunits, RNA, and protein components. Ribosome biogenesis and its emergence as a frontier research area for translational potential in cancer and other diseases are also discussed. In addition, the book explores current developments in ribosome research like the emergence of ribosomopathies, how deregulation of ribosome biogenesis can impact disease mechanisms and aging, and the discovery of specialized ribosomes that have specific functions that may translate differentially with consequences on normal and pathological processes. Emerging Concepts in Ribosome Structure, Biogenesis, and Functionprovidesfundamental coverage and emerging research on ribosomes, biogenesis, and their structure and function and is a resourceful introduction for new researchers and those engaged in interdisciplinary ribosomal research.
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