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Bioactive Peptides Produced by Limited Proteolysis, C. M. Camargo, Beatriz L. Fernandes, Lilian Cruz


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Автор: C. M. Camargo, Beatriz L. Fernandes, Lilian Cruz
Название:  Bioactive Peptides Produced by Limited Proteolysis
ISBN: 9781615043682
Издательство: Mare Nostrum (Eurospan)
Классификация:

ISBN-10: 1615043683
Обложка/Формат: Paperback
Страницы: 92
Вес: 0.18 кг.
Дата издания: 30.05.2012
Серия: Colloquium series on neuropeptides
Язык: English
Иллюстрации: Illustrations, black and white
Размер: 235 x 188 x 6
Читательская аудитория: General (us: trade)
Ключевые слова: Neurology & clinical neurophysiology
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Поставляется из: Англии
Описание: Proteins are considered supremely important for the organization, survival, and functioning of living organisms. They were considered stable and static molecules until the early 1940s, when Rudolph Schoenheimer demonstrated that proteins exist in a constant dynamic process of synthesis and degradation (proteostasis), absolutely essential for life. Since then, general and limited protein degradation became some of the most fascinating aspects of biological sciences. This book is focused on a particular aspect of protein degradation, namely, limited proteolysis, which gives rise to bioactive peptides as a result of the enzymatic action of proteinases and peptidases, which are enzymes that hydrolyze specific peptide bonds of proteins and peptides, respectively. In a broad sense, bioactive peptides are any fragment of endogenous or exogenous proteins able to elicit either physiological or pathological activities. Here, we aim at presenting to the readers that bioactive peptides are not merely produced through random processes during protein degradation, but rather through a well-organized enzymatic process that is deeply integrated in the homeostatic processes of living organisms.


Analysis of Post-Translational Modifications and Proteolysis in Neuroscience

Автор: Grant
Название: Analysis of Post-Translational Modifications and Proteolysis in Neuroscience
ISBN: 1493934708 ISBN-13(EAN): 9781493934706
Издательство: Springer
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Цена: 19564.00 р.
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Описание: This volume highlights proteomics studies of quantitative PTM changes in both peripheral and central nervous system proteomes utilizing the most recent advances in mass spectrometry. Chapters include practical information pertaining to the fundamentals of sample preparation, liquid chromatography, and tandem mass spectrometry instrumental analysis and will elucidate best practices in the interpretation of data using modern bioinformatics approaches. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.Authoritative and practical, Analysis of Post-Translational Modifications and Proteolysis in Neuroscience aims to ensure successful results in the further study of this vital field.

Amino Acids, Peptides and Proteins: Volume 41

Автор: Ryadnov
Название: Amino Acids, Peptides and Proteins: Volume 41
ISBN: 1782625372 ISBN-13(EAN): 9781782625377
Издательство: Royal Society of Chemistry
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Цена: 66517.00 р.
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Описание: Amino Acids, Peptides and Proteins comprises a comprehensive and critical review of significant developments at the biology and chemistry interface. Compiled by leading researchers in their subject, this volume incorporates current trends and emerging areas for example discovery and validation of novel protein/peptide biomarkers, proteins and peptides for the diagnosis and therapy of a parasite infection and surface and interface analysis of functional proteins and peptides. Appealing broadly to researchers in academia and industry, it will be of great benefit to any researcher wanting a succinct reference to developments now and looking to the future.

Modern Tools for the Synthesis of Complex Bioactive Molecules

Автор: Arseniyadis
Название: Modern Tools for the Synthesis of Complex Bioactive Molecules
ISBN: 0470616180 ISBN-13(EAN): 9780470616185
Издательство: Wiley
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Цена: 22643.00 р.
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Описание: An overview of the new technologies that have revolutionized organic chemistry and allowed easy access to complex bioactives, this book brings modern synthetic techniques and bioactives together. The synthesis of structurally complex molecules has become a real challenge for the synthetic community.

Green Chemistry: Synthesis of Bioactive Heterocycles

Автор: K. L. Ameta; Anshu Dandia
Название: Green Chemistry: Synthesis of Bioactive Heterocycles
ISBN: 8132229010 ISBN-13(EAN): 9788132229018
Издательство: Springer
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Цена: 15672.00 р.
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Описание: The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc.

Neuropeptides and Other Bioactive Peptides: From Discovery to Function

Автор: Lloyd D. Fricker
Название: Neuropeptides and Other Bioactive Peptides: From Discovery to Function
ISBN: 1615045066 ISBN-13(EAN): 9781615045068
Издательство: Mare Nostrum (Eurospan)
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Цена: 6237.00 р.
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Описание: Neuropeptides and peptide hormones represent the largest class of chemical messengers that transmit information from one cell to another. In this review, several decades of research on peptides in cell-cell signaling are summarized, with a focus on neuropeptide discovery, biosynthesis, and function. In addition to covering the well-studied aspects of neuropeptides, emerging concepts are discussed, including classical versus non-classical neuropeptides and direct versus indirect neuropeptides. Other potential functions for peptides in intercellular and intracellular signaling are also discussed.

Regulated Proteolysis in Microorganisms

Автор: David A. Dougan
Название: Regulated Proteolysis in Microorganisms
ISBN: 9400759398 ISBN-13(EAN): 9789400759398
Издательство: Springer
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Цена: 23757.00 р.
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Описание: This book contains an extensive collection of critical reviews, from leading researchers in the field of regulated protein degradation. It covers the role of regulated proteolysis in a range of microorganisms (from Gram positive, Gram negative and pathogenic bacteria to Archaea and the Baker`s yeast Saccharomyces cerevisiae).

Proteolysis in Wound Repair

Автор: Giovanni Abatangelo; Luigi Donati; Wolfgang Vansch
Название: Proteolysis in Wound Repair
ISBN: 354060815X ISBN-13(EAN): 9783540608158
Издательство: Springer
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Цена: 12157.00 р.
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Описание: As far as the repair process is concerned, a failure in such regulation may result in abnormal wound healing ranging from nonhealing wounds to hyper- trophic scarring. For example, the importance of debridement in nor- mal and especially in poorly healing wounds has become much clearer in the recent past.

Chemistry of Proteolysis

Автор: Vladimir K. Antonov
Название: Chemistry of Proteolysis
ISBN: 3662009811 ISBN-13(EAN): 9783662009819
Издательство: Springer
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Цена: 6986.00 р.
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Описание: A first edition of this book appeared in Russian language in 1983. The book retains the presentation of the previous edition and yet enlarges the scope to cover the methods for site-directed mutagenesis of amide hydrolases, catalyti- cally active antibodies, etc.

Analysis of Post-Translational Modifications and Proteolysis in Neuroscience

Автор: Jennifer Elizabeth Grant; Hong Li
Название: Analysis of Post-Translational Modifications and Proteolysis in Neuroscience
ISBN: 1493980580 ISBN-13(EAN): 9781493980581
Издательство: Springer
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Цена: 13974.00 р.
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Описание:

1. Proteomic Analysis of Post-Translational Modifications in Neurobiology

Hongbo Gu, Matthew P. Stokes, and Jeffrey C. Silva

2. A Boronic Acid-based Enrichment for Site-specific Identification of the N-glycoproteome using MS-based Proteomics

Haopeng Xiao, George X. Tang, Weixuan Chen, and Ronghu Wu

3. Site-specific Localization of D-Amino Acids in Bioactive Peptides by Ion Mobility Spectrometry

Chenxi Jia, Christopher B. Lietz, Qing Yu, and Lingjun Li

4. Quantitative Profiling of Reversible Cysteome Modification under Nitrosative Stress

Yue-Ting Wang, Sujeewa C. Piyankarage, and Gregory R. J. Thatcher

5. Label-free LC-MS/MS Comparative Analysis of Protein S-nitrosome in Synaptosomes from Wild Type and APP Transgenic Mice

Monika Zaręba-Koziol, Maciej Lalowski, and Aleksandra Wyslouch-Cieszyńska

6. Proteomics Identification of Redox-Sensitive Nuclear Protein Targets Of Human Thioredoxin 1 from SHSY-5Y Neuroblastoma Cell Line

Mohit Raja Jain, Changgong Wu, Qing Li, Chuanlong Cui, Huacheng Dai, and Hong Li

7. Identification and Quantification of K63-Ubiquitinated Proteins in Neuronal Cells by Hi

gh-

Resolution Mass Spectrometry

Gustavo Monteiro Silva, Wei Wei, Sandhya Manohar, and Christine Vogel

8. Phosphorylation Site Profiling of NG108 Cells Using Quadrupole/Orbitrap Mass

Spectrometry

Fang-Ke Huang, Guoan Zhang, and Thomas A. Neubert

9. Phosphoproteomics of Tyrosine Kinases in the Nervous System

Robert J. Chalkley and

Ralph A. Bradshaw

10. Analysis of PINK1 and CaMKII Substrates Using Mass Spectrometry-Based Proteomics

Yan Li, Lesley A. Kane, Michael A Bemben, and Katherine W Roche

11. Liquid Chromatography-Tandem Mass Spectrometry Analysis of Tau Phosphorylation

Jhoana Mendoza, Georgia Dolios, and Rong Wang

12. Identification of Protease Substrates in Complex Proteomes by iTRAQ-TAILS

Tobias Kockmann, Nathalie Carte, Samu Melkko, and Ulrich auf dem Keller

13. Proteolytic P

rocessing of Neuropeptides

Lloyd D. Fricker

14 Isotope Dilution Analysis of Myelin Basic Protein Degradation after Brain Injury

Andrew K Ottens

15. Identification and Characterization of Protein Post-Translational Modifications by

Differential Fluorescent Labeling

Eric D. Hamlett, Cristina Osorio, and Oscar Alzate

16 Mass

Spectrometric Detection of Detyrosination and Polyglutamyation on the C-Terminal Region of Brain Tubulin

Yasuko Mori, Alu Konno, Mitsutoshi Setou, and Koji Ikegami

17. Determination of polyhydroxybutyrate (PHB) Post-Translational Modifications of Proteins Using Mass Spectrometry

Tong Liu, Wei Chen, Stacey Pan, Chuanlong Cui, Hong Li, and Eleonora Zakharian

Mid-size drugs based on peptides and peptidomimetics.

Автор: Hirokazu Tamamura, Takuya Kobayakawa, Nami Ohashi
Название: Mid-size drugs based on peptides and peptidomimetics.
ISBN: 9811076901 ISBN-13(EAN): 9789811076909
Издательство: Springer
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Цена: 6986.00 р.
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Описание: This brief describes studies conducted by the authors on mid-size drugs utilizing peptides and peptidomimetics, and on the development of anti-HIV agents. To date, several peptidomimetics that mimic primary, secondary, and tertiary structures of peptides have been developed to maintain and improve biological activities and actions of peptides.

Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites

Автор: G. Lancini; R. Lorenzetti
Название: Biotechnology of Antibiotics and Other Bioactive Microbial Metabolites
ISBN: 0306446030 ISBN-13(EAN): 9780306446030
Издательство: Springer
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Цена: 26120.00 р.
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Описание: An introductory text for the vast and scattered literature relating to the biotechnology of microbial secondary metabolites. This book discusses general biology, biosynthesis, the search for novel metabolites, and techniques for strain improvement. It is useful to undergraduate and graduate students.

Green Chemistry: Synthesis of Bioactive Heterocycles

Автор: K. L. Ameta; Anshu Dandia
Название: Green Chemistry: Synthesis of Bioactive Heterocycles
ISBN: 8132218493 ISBN-13(EAN): 9788132218494
Издательство: Springer
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Цена: 18284.00 р.
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Описание: The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc.


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