Описание: This book identifies an important aspect in the analysis of urban change in the late twentieth century by highlighting the significance of the senses in the constitution of urban life.
Описание: Over the past decade, the study of microglial cells has gained increasing importance, in particular for those working in the fields of degeneration and regeneration. Microglia in the Regenerating and Degenerating CNS supports the assertion that understanding microglial biology could perhaps be pivotal for unraveling the pathogenetic mechanisms that underlie Alzheimer's disease, currently the most widely studied disorder of the central nervous system. In addition, microglia are also critical for understanding the sequelae of traumatic brain and spinal cord injury, and for the vitally important post-traumatic repair processes. This book gives an up to date account of the role of microglia in degeneration and regeneration of the nervous system and also reviews microglial cell function and physiology. Cellular neurobiologists will find that this is a valuable guide to the importance and role of microglia in the CNS.
Автор: Jane Frank Название: Regenerating Regional Culture ISBN: 3319650351 ISBN-13(EAN): 9783319650357 Издательство: Springer Рейтинг: Цена: 12577.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores the significance of the international book town movement and its impact on contemporary society. It examines how book towns have emerged and how their culture and unique characteristics help to explain a steadily growing phenomenon that has enabled peripheral communities around the world to reclaim their economic futures and impact on the cultural sphere as increasingly powerful sites and sources of creativity.
Regenerating Regional Culture assesses why, at a time when the book industry is experiencing a profound transformation, book towns are proliferating in Europe and across the globe. It acknowledges the role of the book as a catalyst for this significant cultural activity and development. The book is shown to be a unique and pivotal item of cultural consumption, a remarkable artefact and, more than ever before, a springboard for contemporary cultural debate. This work investigates how the reanimation of these 'down-on-their-luck' towns is attracting, through a combination of nostalgia, history and cultural heritage, a growing middle class cohort who seek both intellectual stimulation and opportunities for serious leisure and wellbeing.
This book will prove to be a useful resource for understanding the impacts of book towns on art, culture and society while also offering insightful research for those involved in existing or future development of book towns and other community cultural projects.
Автор: Marques, Alexandra Название: Skin Tissue Models for Regenerative Medicine ISBN: 0128105453 ISBN-13(EAN): 9780128105450 Издательство: Elsevier Science Рейтинг: Цена: 16666.00 р. Наличие на складе: Поставка под заказ.
Описание:
Skin Tissue Models for Regenerative Medicine provides a translational link for biomedical researchers on the interdisciplinary approaches to skin regeneration. As the skin is the largest organ in the body, engineered substitutes have critical medical application to patients with disease and injury - from burn wounds and surgical scars, to vitiligo, psoriasis and even plastic surgery. This volume offers readers preliminary description of the normal structure and function of mammalian skin, exposure to clinical problems and disease, coverage of potential therapeutic molecules and testing, skin substitutes, models as study platforms of skin biology and emerging technologies.
The editors have created a table of contents which frames the relevance of skin tissue models for researchers as platforms to study skin biology and therapeutic approaches for different skin diseases, for clinicians as tissue substitutes, and for cosmetic and pharmaceutical industries as alternative test substrates that can replace animal models.
Offers descriptions of the normal structure/function of mammalian skin, exposure to clinical problems, and more
Presents coverage of skin diseases (cancer, genodermatoses, vitiligo and psoriasis) that extends to clinical requirements and skin diseases in vitro models
Addresses legal requirements and ethical concerns in drugs and cosmetics in vitro testing
Edited and authored by internationally renowned group of researchers, presenting the broadest coverage possible
Описание: Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. . The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. . In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics.
Автор: Warburton D. Название: Stem cells, tissue engineering and regenerative medicine ISBN: 9814612774 ISBN-13(EAN): 9789814612777 Издательство: World Scientific Publishing Рейтинг: Цена: 27720.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Stem cells, tissue engineering and regenerative medicine are fast moving fields with vastly transformative implications for the future of health care and capital markets. This book will show the state of the art in the translational fields of stem cell biology, tissue engineering and regenerative medicine. The state of developments in specific organ systems, where novel solutions to organ failure are badly needed such as the lungs, kidney and so forth, are discussed in various chapters. These present and future advances are placed in the context of the overall field, offering a comprehensive and quick up-to-date drink from the fountain of knowledge in this rapidly emerging field.
This book provides an investigator-level overview of the current field accessible to the educated scientific generalist as well as a college educated readership, undergraduates and science writers, educators and professionals of all kinds.
Автор: H.D. Perez; B. Mitrovic; A. Baron Van Evercooren Название: Opportunities and Challenges of the Therapies Targeting CNS Regeneration ISBN: 3642421482 ISBN-13(EAN): 9783642421488 Издательство: Springer Рейтинг: Цена: 20962.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: New Strategies for CNS Repair.- Heterogeneity of Multiple Sclerosis: Implications for Therapy Targeting Regeneration.- The Neuroprotective Effect of Inflammation: Implications for the Therapy of Multiple Sclerosis.- Fibroblast Growth Factors in Oligodendrocyte Physiology and Myelin Repair.- White Matter Progenitor Cells Reside in an Oligodendrogenic Niche.- At the Interface of the Immune System and the Nervous System: How Neuroinflammation Modulates the Fate of Neural Progenitors In Vivo.- Remyelination and Restoration of Axonal Function by Glial Cell Transplantation.- Gene and Stem Cell Therapy for Autoimmune Demyelination.- Novel Gene Therapeutic Strategies for Neurodegenerative Diseases.- Measuring Injury and Repair of Myelin and Neurons in Multiple Sclerosis.
Автор: Lee, Sang Jin Название: In Situ Tissue Regeneration ISBN: 0128022256 ISBN-13(EAN): 9780128022252 Издательство: Elsevier Science Рейтинг: Цена: 19875.00 р. Наличие на складе: Поставка под заказ.
Описание:
In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body's ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body's own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications.
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