The Actin Cytoskeleton and the Regulation of Cell Migration, Jonathan M. Lee
Автор: Manfred Schliwa Название: The Cytoskeleton ISBN: 3709176697 ISBN-13(EAN): 9783709176696 Издательство: Springer Рейтинг: Цена: 15372.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The term cytoskeleton has become firmly established in today`s scientific vocabulary. Since then, the modern field of research on the structural organization of the cytoplasm has turned into one of the most productive and rapidly expanding research areas in Cell Biology today.
Автор: Philippe Jeanteur Название: Cytoskeleton and Small G Proteins ISBN: 3642636594 ISBN-13(EAN): 9783642636592 Издательство: Springer Рейтинг: Цена: 27950.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Animal cells present an extreme variability in their shapes in relation to their physiological properties. For instance, fibroblastic cells are tightly attached to the extra-cellular matrix and display a flattened, spindle-shaped morphology. Neuronal cells self-organize as a network through a complex branching of dendrites and a long axonal extension. Resting peripheral blood lymphocytes are poorly adhesive and maintain a spherical, smooth shape, while macroph- ages produce many pseudopodal extensions involved in the recognition of foreign molecules. In addition to the variability of the morphology of the cells that constitute different organs, many cell types also modify dynamically their morphology in response to environmental changes, leading to differential cell motility, migration, adhesion, polarity or intercellular contacts. This wide plasticity of cell morphology is promoted and maintained by the cytoskeleton, which is composed of the three interconnected actin micro filaments, tubulin microtubules and intermediate filaments networks, all capable of assembly and disassembly. Over the past few years, the Rho family of Ras-like GTPases emerged as key proteins that mediate extracellular signalling pathways leading to the forma- tion of polymerized actin-containing structures such as ruffles, lamellipodia and filopodia. Since the discovery of the first member RhoA in 1985, 13 mem- bers have so far been characterized in human cells. Most of Rho proteins are highly conserved between species as distant as yeast, slime mold, insects and mammals, which points to their fundamental role in cellular physiology.
Actin Cytoskeleton in Cancer Progression and Metastasis Part A, Volume 355, in the International Review of Cell and Molecular Biology series provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response.
Автор: Christopher J. Staiger; Frantisek Baluska; D. Volk Название: Actin: A Dynamic Framework for Multiple Plant Cell Functions ISBN: 0792364120 ISBN-13(EAN): 9780792364122 Издательство: Springer Рейтинг: Цена: 47377.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Actin is an abundant protein that comprises a dynamic polymeric network present in various eukaryotic cells, known as the actin cytoskeleton. This work puts together a diverse collection of topics, contributed by international experts, related to the plant actin cytoskeleton.
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