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Computational methods for drug repurposing, 


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Цена: 20962.00р.
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Название:  Computational methods for drug repurposing
ISBN: 9781493989546
Издательство: Springer
Классификация:





ISBN-10: 1493989545
Обложка/Формат: Hardcover
Страницы: 332
Вес: 0.83 кг.
Дата издания: 14.12.2018
Серия: Methods in molecular biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 80 tables, color; 80 illustrations, color; 21 illustrations, black and white; approx. 320 p. 101 illus., 80 illus. in color. with online files/update.
Размер: 184 x 260 x 27
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This detailed book explores techniques commonly used for research into drug repurposing, a well-known strategy to find alternative indications for drugs which have already undergone toxicology and pharma-kinetic studies but have failed later stages during the development, via computational methods. Thereby, it addresses the intense challenges of identifying the appropriate type of algorithm and relevant technical information for computational repurposing. Written for the highly successful Methods in Molecular Biology series, the authors of each chapter use their experience in the field to describe the implementation and successful use of a specific repurposing method thus providing lab-ready instruction.
Authoritative and practical, Computational Methods for Drug Repurposing serves as an ideal guide to researchers interested in this vital area of drug development.

Дополнительное описание: Methods for Discovering and Targeting Druggable Protein-Protein Interfaces and Their Application to Repurposing.- Performing an In Silico Repurposing of Existing Drugs by Combining Virtual Screening and Molecular Dynamics Simulation.- Repurposing Drugs Ba



Computational Methods for Three-Dimensional Microscopy Recon

Название: Computational Methods for Three-Dimensional Microscopy Recon
ISBN: 1461495202 ISBN-13(EAN): 9781461495208
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Computational Methods for Three-Dimensional Microscopy Reconstruction

Computational Neuroscience of Drug Addiction

Автор: Boris Gutkin; Serge H. Ahmed
Название: Computational Neuroscience of Drug Addiction
ISBN: 1461429404 ISBN-13(EAN): 9781461429401
Издательство: Springer
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Цена: 28732.00 р.
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Описание: This book describes the torrent of data generated through research on the neurobiology and psychology of drug addiction, and discusses the role of mathematical and computational modeling in the development of more testable and rigorous models of addiction.

Computational Methods in Systems Biology

Автор: Monika Heiner; Adelinde M. Uhrmacher
Название: Computational Methods in Systems Biology
ISBN: 3540885617 ISBN-13(EAN): 9783540885610
Издательство: Springer
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Цена: 12157.00 р.
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Описание: Constitutes the refereed proceedings of the 6th International Conference on Computational Methods in Systems Biology, CMSB 2008, held in Rostock, Germany, in September 2008. This book focuses on modeling approaches, including process algebra, simulation approaches, analysis methods, in particular model checking and flux analysis, and case studies.

Computational Intelligence Methods for Bioinformatics and Biostatistics

Автор: Massimo Bartoletti; Annalisa Barla; Andrea Braccia
Название: Computational Intelligence Methods for Bioinformatics and Biostatistics
ISBN: 3030141594 ISBN-13(EAN): 9783030141592
Издательство: Springer
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Цена: 8104.00 р.
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Описание: This book constitutes the thoroughly refereed post-conference proceedings of the 14th International Meeting on Computational. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medical informatics, computational approaches to life sciences in general.

Optical Spectroscopy and Computational Methods in Biology and Medicine

Автор: Baranska
Название: Optical Spectroscopy and Computational Methods in Biology and Medicine
ISBN: 9400778317 ISBN-13(EAN): 9789400778313
Издательство: Springer
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Цена: 36570.00 р.
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Описание: This book offers a comprehensive review of progress in vibrational spectroscopic techniques and chemometric methods and their applications in chemistry, biology and medicine. Surveys recent advances, potential exploitations of the theory and new applications.

Complex Models and Computational Methods in Statistics

Автор: Matteo Grigoletto; Francesco Lisi; Sonia Petrone
Название: Complex Models and Computational Methods in Statistics
ISBN: 8847028701 ISBN-13(EAN): 9788847028708
Издательство: Springer
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Цена: 6986.00 р.
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Описание: This volume details statistical methods for high-dimensional problems. It includes a wide range of statistical applications.

Computational Methods in Systems Biology

Автор: Bartocci
Название: Computational Methods in Systems Biology
ISBN: 3319451766 ISBN-13(EAN): 9783319451763
Издательство: Springer
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Цена: 9083.00 р.
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Описание: This book constitutes the refereed proceedings of the 14th International Conference on Computational Methods in Systems Biology, CMSB 2016, held in Cambridge, UK, in September 2016. The topics include formalisms for modeling biological processes; frameworks for model verification, validation, analysis, and simulation of biological systems;

RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods

Автор: Jan Gorodkin; Walter L. Ruzzo
Название: RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods
ISBN: 162703708X ISBN-13(EAN): 9781627037082
Издательство: Springer
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Цена: 27950.00 р.
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Описание: This new publication in the Methods in Molecular Biology series sets out detailed protocols for the targeted bioinformatics procedures dedicated to RNA structure. It features practical and algorithmic approaches as well as expert problem-solving advice.

Computational Methods in Systems Biology

Автор: Milan ?e?ka; David ?afr?nek
Название: Computational Methods in Systems Biology
ISBN: 331999428X ISBN-13(EAN): 9783319994284
Издательство: Springer
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Цена: 8384.00 р.
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Описание: This book constitutes the refereed proceedings of the 16th International Conference on Computational Methods in Systems Biology, CMSB 2018, held in BRNO, Czech Republic, in September 2018. The 15 full and 7 short papers presented together with 5 invited talks were carefully reviewed and selected from 46 submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology; parameter and model inference from experimental data; automated parameter and model synthesis; model integration and biological databases; multi-scale modeling and analysis methods; design, analysis, and verification methods for synthetic biology; methods for biomolecular computing and engineered molecular devices.Chapters 3, 9 and 10 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology

Автор: David Holcman
Название: Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology
ISBN: 3319626264 ISBN-13(EAN): 9783319626260
Издательство: Springer
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Цена: 15372.00 р.
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Описание: Part I: Stochastic Chemical Reactions.- Test Models for Statistical Inference: Two-Dimensional Reaction Systems Displaying Limit Cycle Bifurcations and Bistability.- Importance Sampling for Metastable and Multiscale Dynamical Systems.- Multiscale Simulation of Stochastic Reaction-diffusion Networks.- Part II: Stochastic Numerical Approaches, Algorithms and Coarse-Grained Simulations.- Numerical Methods for Ergodic SDEs: When Stochastic Integration Meets Geometric Integration.- Stability and Strong Convergence for Spatial Stochastic Kinetics.- The T cells in an Ageing Virtual Mouse.- Part III: Analysis of Stochastic Dynamical Systems for Modeling Cell Biology.- Model reduction for Stochastic Reaction Systems.- ZI-closure Scheme: A Method to Solve and Study Stochastic Reaction Networks.- Deterministic and Stochastic Becker-Dцring Equations: Past and Recent Mathematical Developments.- Coagulation-Fragmentation with a Finite Number of Particles: Models, Stochastic Analysis and Applications to Telomere Clustering and Viral Capsid Assembly.- A Review of Stochastic and Delay Simulation Approaches in both Time and Space in Computational Cell Biology.- Part IV: Diffusion Processes and Stochastic Modeling.- Recent Mathematical Models of Axonal Transport.- Stochastic Models for Evolving Cellular Populations of Mitochondria: Disease, Development, and Ageing.- Modeling and Stochastic Analysis of the Single Photon Response.- A Phenomenological Spatial Model for Macro-ecological Patterns in Species-rich Ecosystems.

Computational Methods in Protein Evolution

Автор: Sikosek
Название: Computational Methods in Protein Evolution
ISBN: 1493987356 ISBN-13(EAN): 9781493987351
Издательство: Springer
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Цена: 18167.00 р.
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Описание: This volume presents a diverse collection of methodologies used to study various problems at the protein sequence and structure level. The chapters in this book look at issues ranging from broad concepts like protein space to specifics like antibody modeling. Topics include point mutations, gene duplication, de novo emergence of new genes, pairwise correlated mutations, ancestral protein reconstruction, homology modelling, protein stability and dynamics, and protein-protein interactions. The book also covers a wide range of computational approaches, including sequence and structure alignments, phylogenies, physics-based and mathematical approaches, machine learning, and more. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and prerequisites, step-by-step, readily reproducible computational protocols (using command line or graphical user interfaces, sometimes including computer code), and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Computational Methods in Protein Evolution is a valuable resource that offers useful workflows and techniques that will help both novice and expert researchers working with proteins computationally.

Optical Spectroscopy and Computational Methods in Biology and Medicine

Автор: Malgorzata Baranska
Название: Optical Spectroscopy and Computational Methods in Biology and Medicine
ISBN: 9402400117 ISBN-13(EAN): 9789402400113
Издательство: Springer
Рейтинг:
Цена: 36570.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book offers a comprehensive review of progress in vibrational spectroscopic techniques and chemometric methods and their applications in chemistry, biology and medicine. Surveys recent advances, potential exploitations of the theory and new applications.


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