Rosenhouse-Dantsker Avia, Bukiya Anna N. Direct Mechanisms in Cholesterol Modulation of Protein Function 9783030142643

Варианты приобретения

Цена: 13974.00р.
Кол-во:
Наличие: Поставка под заказ. Есть в наличии на складе поставщика.
Склад Америка: Есть
При оформлении заказа до: 2025-07-28
Ориентировочная дата поставки: Август-начало Сентября
При условии наличия книги у поставщика.

Добавить в корзину

в Мои желания

Автор: Rosenhouse-Dantsker Avia, Bukiya Anna N.
Название: Direct Mechanisms in Cholesterol Modulation of Protein Function
ISBN: 9783030142643
Издательство: Springer
Классификация:

Медицинское оборудования и методики его эксплуатации

Биохимия

Белки

Жиры

Клеточная биология (цитология)

Компьютерные сети и коммуникации

ISBN-10: 3030142647
Обложка/Формат: Hardcover
Страницы: 168
Вес: 0.43 кг.
Дата издания: 27.05.2019
Серия: Advances in experimental medicine and biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 47 tables, color; 50 illustrations, color; 1 illustrations, black and white; ix, 168 p. 51 illus., 50 illus. in color.
Размер: 234 x 156 x 11
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: In this book, renowned scientists describe how cholesterol interacts with various proteins. Recent progress made in the high-resolution visualization of cholesterol-protein interactions using crystallography and cryogenic electron microscopy has substantially advanced the knowledge of critical features. These features enable specific recognition of the cholesterol molecule by proteins, a process that was built on earlier studies using binding assays, computational modeling and site-directed mutagenesis. Direct Mechanisms in Cholesterol Modulation of Protein Function offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via direct sensing. Its nine chapters are organized into two distinct parts. In the first part, the chapters introduce the reader to the general characteristics of cholesterol binding sites in proteins. This part starts with a tour into common cholesterol recognition motifs, followed by an overview of the major classes of steroid-binding proteins. It then continues with two chapters that present a comprehensive analysis of molecular and structural characteristics of cholesterol binding sites in transmembrane and soluble protein domains. In the second part of the book, examples of cholesterol binding sites and consequences of specific cholesterol recognition for protein function are presented for G protein-coupled receptors, ion channels and cholesterol-transporting proteins. The book is valuable for undergraduate and graduate students in biochemistry and nutrition, as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems.
Дополнительное описание: Introduction.- Direct binding of cholesterol to proteins.- Cholesterol-recognition motifs in membrane proteins.- Molecular determinants of cholesterol binding to proteins: overview of crystallographic studies.- Crystallographic studies of steroid-protein

Direct Mechanisms in Cholesterol Modulation of Protein Function, Rosenhouse-Dantsker Avia, Bukiya Anna N.