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Thymus Transcriptome and Cell Biology, Passos Geraldo A.


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Автор: Passos Geraldo A.
Название:  Thymus Transcriptome and Cell Biology
ISBN: 9783030120399
Издательство: Springer
Классификация:




ISBN-10: 3030120392
Обложка/Формат: Hardcover
Страницы: 318
Вес: 0.65 кг.
Дата издания: 06.05.2019
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 25 tables, color; 23 illustrations, color; 7 illustrations, black and white; xvii, 318 p. 30 illus., 23 illus. in color.; 25 tables, color; 23 illustr
Размер: 234 x 156 x 21
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume focuses on challenging field in biomedicine that is the genetic control of central immune tolerance. It covers the thymus development, their cellular components and their respective function, the peculiar gene expression profiling (transcriptome) found in the medullary thymic epithelial cells (mTECs) that are implicated in the self-representation in the thymus, the Autoimmune regulator (Aire) gene, the mutations in this gene and manifestation of autoimmune diseases, and the role of cell-cell interactions within the thymus with implications in the negative selection (elimination) of nascent autoreactive T cells in preventing aggressive autoimmunity. The thymus gland is a lymphoid organ implicated in the maturation, differentiation and selection of T cells. This organ is gained more and more attention in different biomedical research labs worldwide due to its function that is associated with the control of immune homeostasis in the body, establishing the central immune tolerance and preventing the onset of autoimmune diseases.
Дополнительное описание: 1. History of the thymus: From a vestigial organ to the programming of immunological self-tolerance.- 2. Thymus Ontogeny and Development.- 3. The Ins and Outs of Thymic Epithelial Cell Differentiation and Function.- 4. T-Cell Development: From T-Lineage S



Usa

Автор: Passos, John
Название: Usa
ISBN: 1883011140 ISBN-13(EAN): 9781883011147
Издательство: Random House (USA)
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Цена: 4138.00 р.
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Описание: Unique among American books for its epic scope and panoramic social sweep, U.S.A. has long been acknowledged as a monument of modern fiction. Now The Library of America presents an exclusive one-volume edition of this enduring masterwork by John Dos Passos, including for the first time detailed notes and a chronicle of the world events that serve as a backdrop.

In the novels that make up the trilogy--The 42nd Parallel, 1919, and The Big Money--Dos Passos creates an unforgettable collective portrait of America, shot through with sardonic comedy and brilliant social observation. He interweaves the careers of his characters and the events of their time with a narrative verve and breathtaking technical skill that make U.S.A. among the most compulsively readable of modern classics.

A startling range of experimental devices captures the textures and background noises of twentieth-century life: "Newsreels" with blaring headlines; autobiographical "Camera Eye" sections with poetic stream-of-consciousness; "biographies" evoking emblematic historical figures like J.P. Morgan, Henry Ford, John Reed, Frank Lloyd Wright, Thorstein Veblen, and the Unknown Soldier. Holding everything together is sheer storytelling power, tracing dozens of characters from the Spanish-American War to the onset of the Depression.

The U.S.A. trilogy is filled with American speech: labor radicals and advertising executives, sailors and stenographers, interior decorators and movie stars. Their crisscrossing destinies take in wars and revolutions, desperate love affairs and harrowing family crises, corrupt public triumphs and private catastrophes, in settings that include the trenches of World War I, insurgent Mexico, Hollywood studios in the silent era, Wall Street boardrooms, and the tumultuous streets of Boston just before the execution of Sacco and Vanzetti.

The volume contains newly researched chronologies of Dos Passos's life and of world events cited in U.S.A., notes, and an essay on textual selection.

Dificil Recomeco

Автор: Fabbri Umberto, Campos Geraldo
Название: Dificil Recomeco
ISBN: 0615970273 ISBN-13(EAN): 9780615970271
Издательство: Неизвестно
Цена: 1724.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: O destino um s , mas por onde, como e quando chegar somos n s quem escolhemos. Nos tr s livros - Recome ar a Viver, Novos Desafios e Dif cil Recome o - Orlando mostra-nos em sua hist ria, as dificuldades e alegrias daqueles que aceitam os desafios do recome o e, mesmo conscientes dos obst culos, sabem que nunca estiveram e nunca estar o s s... A saga de nosso irm o retrata a jornada da maioria de n s, nossas ang stias, inseguran as e ansiedades. Mostra tamb m a miseric rdia divina que aplica suas leis redentoras sem jamais deixar de fornecer os recursos necess rios para que tenhamos sempre xito em nossas conquistas. Geraldo Campos

Manhattan Transfer

Автор: Dos Passos John Roderigo
Название: Manhattan Transfer
ISBN: 0618381864 ISBN-13(EAN): 9780618381869
Издательство: Неизвестно
Цена: 2344.00 р.
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Описание: Considered by many to be John Dos Passos's greatest work, Manhattan Transfer is an expressionistic picture of New York (New York Times) in the 1920s that reveals the lives of wealthy power brokers and struggling immigrants alike. From Fourteenth Street to the Bowery, Delmonico's to the underbelly of the city waterfront, Dos Passos chronicles the lives of characters struggling to become a part of modernity before they are destroyed by it.
More than seventy-five years after its first publication, Manhattan Transfer still stands as a novel of the very first importance (Sinclair Lewis). It is a masterpeice of modern fiction and a lasting tribute to the dual-edged nature of the American dream.

Trojan Horse: After the Blood: Book Two

Автор: Cruz Geraldo
Название: Trojan Horse: After the Blood: Book Two
ISBN: 1790325757 ISBN-13(EAN): 9781790325757
Издательство: Неизвестно
Цена: 3095.00 р.
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Описание: The enemy of my enemy is my friend...Detective Jake Castillo returns in TROJAN HORSE, the second installment of the AFTER THE BLOOD saga. When a misguided act of desperation leads to nightclub owner Nara Lopez being brutally assaulted, Melissa Colon turns to the only two men she can trust to find her best friend's attackers - her brothers. But can Jake Castillo & Carlito Colon put their own violent history behind them long enough to find out who was behind the assault? As the two bitter enemies attempt to work through their differences, other forces are conspiring against them as Marco Santana seeks retribution against Carlito Colon for his failed assassination attempt several months ago. He enlists the help of Marilyn Moreno, the queen-pin of Miami's most powerful drug cartel, to assist him in taking control of New York City's criminal underworld. But unknown to Marco, Moreno is making power moves of her own...As Carlito continues to make enemies in his quest to reclaim his former glory, Jake also has his own score to settle as he enters the corrupt world of prizefighting to investigate the brutal murder of his friend Nick Rodrigo, a champion mixed martial artist with ties to East Harlem's bloody gang scene.

Standing on Common Ground

Автор: Cadava Geraldo L
Название: Standing on Common Ground
ISBN: 0674970896 ISBN-13(EAN): 9780674970892
Издательство: Wiley
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Цена: 4269.00 р.
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Описание: Standing on Common Ground locates the roots of today`s debates over border enforcement in the Sunbelt`s pan-ethnic and transnational history, as cross-border ties in the 1940s among entrepreneurs and politicians, and a flourishing cultural traffic among tourists and students, gave way to economic instability and illegal labor migration.


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